Plant Species


Cumulative plant class count

class name count
rosids 2

Cumulative family count

class name count
Brassicaceae 2
Erysiphaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00007443 External link 512 3-Hydroxy-L-kynurenine
CHEMBL442576
CHEMBL1371152
12 / 3 / 4
C00007604 External link 512 L-Kynurenine
CHEMBL498416
CHEMBL1233899
CHEMBL1377927
7 / 9 / 10
C00007605 External link 512 L-Formylkynurenine

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16719 Kynureninase Enzyme C00007443 C00007604 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00007443 C00007604 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00007443 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00007443 0 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00007443 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00007604 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00007443 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00007443 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00007443 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00007443 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00007604 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00007443 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00007604 2 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00007443 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00007443 1 / 1
O00255 Menin Unclassified protein C00007604 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00007604 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (14)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)