Plant Species


Cumulative plant class count

class name count

Cumulative family count

class name count
Corticiaceae 2
Meruliaceae 1
Auriscalpiaceae 1
Russulaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00003155 External link 512 Isovelleral
CHEMBL518292
CHEMBL1995288
C089286
29 / 34 / 27
C00018191 External link 512 Merulidial
/ (-)-Merulidial
C017491
C00021522 External link 512 Merulactone
C00021523 External link 512 Merulanic acid

Human Protein / Gene in interactions

29 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00003155 4 / 1
P17861 X-box-binding protein 1 Unclassified protein C00003155 1 / 0
Q99700 Ataxin-2 Unclassified protein C00003155 1 / 1
P06746 DNA polymerase beta Enzyme C00003155 0 / 0
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00003155 1 / 4
P02545 Prelamin-A/C Unclassified protein C00003155 11 / 10
P37840 Alpha-synuclein Unclassified protein C00003155 4 / 2
P54132 Bloom syndrome protein Enzyme C00003155 1 / 2
O95977 Sphingosine 1-phosphate receptor 4 EDG receptor C00003155 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00003155 0 / 0
P21453 Sphingosine 1-phosphate receptor 1 EDG receptor C00003155 0 / 0
P42858 Huntingtin Unclassified protein C00003155 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003155 2 / 0
O75496 Geminin Unclassified protein C00003155 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00003155 0 / 0
Q9Y2T6 G-protein coupled receptor 55 Lysophosphatidylinositol receptor C00003155 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003155 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00003155 0 / 0
O75762 Transient receptor potential cation channel subfamily A member 1 Unclassified protein C00003155 1 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00003155 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003155 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00003155 0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00003155 1 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00003155 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003155 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00003155 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00003155 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003155 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00003155 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (34)

OMIM preferred title UniProt
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#208900 Ataxia-telangiectasia; at Q13315
#210900 Bloom syndrome; blm P54132
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#615040 Episodic pain syndrome, familial, 1; feps1 O75762
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#610140 Heart-hand syndrome, slovenian type P02545
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#612371 Major affective disorder 7; mafd7 P17861
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#257220 Niemann-pick disease, type c1; npc1 O15118
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (27)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00094 DNA repair defects P54132 (related)
Q13315 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)