KCF-S cluster No. 263 (22 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (22)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Pseudonocardiaceae	17
Nocardiaceae	5

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (22)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00016052	Vancocin / Diatracin / Vancocine	CHEMBL408673 CHEMBL262777	D014640	94 / 36 / 31	2 / 120
C00016943	Balhimycin		C087127
C00017076	Helvecardin A		C068812
C00017077	Helvecardin B		C068813
C00017124	MM 55266		C071009
C00017125	MM 55268		C071010
C00017605	MM 47761 / Antibiotic MM 47761		C066087
C00017606	MM 49721 / Antibiotic MM 49721 / Antiobiotic MM 49721		C066086
C00017622	A 82846B / LY 264826 / PA 45052A / Chloroeremomycin / Chloroorienticin A / Antibiotic A 82846B / Antibiotic PA 45052A	CHEMBL1688951 CHEMBL1910062	C057893
C00017623	PA 45052B / Dihydrobalhimycin / Chloroorienticin B / Antibiotic PA 45052B	CHEMBL407702 CHEMBL438738	C057894
C00017805	Kibdelin A / Antibiotic AAD 609A		C050685
C00017806	Kibdelin B / Antibiotic AAD 609B		C050686
C00017807	Kibdelin C1 / Antibiotic AAD 609C1		C050687
C00017808	Kibdelin C2		C050688
C00017809	Kibdelin D		C050689
C00017844	Actinoidin A2
C00017873	Chloropolysporin B		C053528
C00017874	Chloropolysporin C		C053529
C00017924	UK 72051 / Orienticin A / Antibiotic UK 72051 / Antibiotic PA 42867A		C056812
C00017925	Orienticin B / Antibiotic PA 42867B		C056813
C00017926	A 82846C / Orienticin C / Dechloroeremomycin / Antibiotic A 82846C
C00017927	Orienticin D

Human Protein / Gene in interactions

94 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00016052	1 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00016052	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00016052	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00016052	2 / 2
P08246	Neutrophil elastase	S1A	C00016052	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00016052	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00016052	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00016052	0 / 0
P29466	Caspase-1	C14	C00016052	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00016052	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00016052	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00016052	2 / 2
O15245	Solute carrier family 22 member 1	Drug uniporter	C00016052	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00016052	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00016052	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00016052	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00016052	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00016052	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00016052	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00016052	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00016052	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00016052	0 / 0
P02768	Serum albumin	Secreted protein	C00016052	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00016052	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00016052	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00016052	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00016052	0 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00016052	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00016052	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00016052	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00016052	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00016052	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00016052	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00016052	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00016052	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00016052	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00016052	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00016052	1 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00016052	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00016052	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00016052	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00016052	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00016052	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00016052	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00016052	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00016052	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00016052	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00016052	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00016052	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00016052	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00016052	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00016052	0 / 0
P08311	Cathepsin G	S1A	C00016052	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00016052	1 / 0
P03956	Interstitial collagenase	M10A	C00016052	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00016052	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00016052	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00016052	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00016052	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00016052	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00016052	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00016052	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00016052	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00016052	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00016052	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00016052	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00016052	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00016052	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00016052	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00016052	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00016052	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00016052	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00016052	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00016052	0 / 0
P03372	Estrogen receptor	NR3A1	C00016052	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00016052	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00016052	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00016052	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00016052	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00016052	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00016052	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00016052	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00016052	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00016052	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00016052	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00016052	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00016052	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00016052	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00016052	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00016052	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00016052	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00016052	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00016052	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00016052	0 / 0

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00016052
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00016052

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions