KCF-S cluster No. 265 (25 metabolites)

Corresponding Phytochemical cluster No. 11


Plant Species


Cumulative plant class count

class name count
Liliopsida 43
asterids 7

Cumulative family count

class name count
Melanthiaceae 34
Liliaceae 9
Solanaceae 4
Asteraceae 3

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Steroid alkaloids 1

metabolites link (1)

br08003 Category KEGG ID KNApSAcK ID
Steroid alkaloids C06543 C00002261

Metabolite list (25)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00002261 External link 512 Solanidine
CHEMBL363703
CHEMBL1534747
CHEMBL1980466
C013255
5 / 5 / 8
C00024019 External link 512 Oblonginine
CHEMBL463130
C00027871 External link 512 Anrakorinine
C00028004 External link 512 Camtschatcanidine
C00028250 External link 512 Epi-verazine
CHEMBL458682
CHEMBL457588
C00028280 External link 512 Fritillarizine
C00028332 External link 512 Hapepunine
C00028412 External link 512 Isorubijervine
C00028414 External link 512 Iso-shinonomenine
C00028841 External link 512 Pingbeinine
/ (-)-Pingbeinine
C065749
C00028946 External link 512 Rubijervine
CHEMBL1512978
CHEMBL1993702
5 / 2 / 3
C00028947 External link 512 Rubivirine
C00029011 External link 512 Shinonomenine
C00029029 External link 512 Solaspiralidine
C00029053 External link 512 Stenophylline B
C043148
C00029184 External link 512 Veracintine
C00029193 External link 512 Veramarine
C00029194 External link 512 Veramiline
CHEMBL463130
C00029197 External link 512 Veramitaline
C00029198 External link 512 Veramivirine
C00029205 External link 512 Verazine
CHEMBL458682
CHEMBL457588
C052979
C00029212 External link 512 Vertaline B
C060393
C00049937 External link 512 25beta-Hydroxyverazine
/ (-)-25beta-Hydroxyverazine
CHEMBL463129
C00049952 External link 512 4beta-Hydroxyverazine
/ (-)-4beta-Hydroxyverazine
CHEMBL464354
CHEMBL517301
C00050217 External link 512 Sarachine
/ (-)-Sarachine
CHEMBL464561

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Enzyme C00002261 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00028946 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00028946 0 / 1
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002261 1 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00028946 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00028946 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00028946 0 / 1
P46063 ATP-dependent DNA helicase Q1 Enzyme C00002261 0 / 0
O00255 Menin Unclassified protein C00002261 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002261 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#302960 Chondrodysplasia punctata 2, x-linked dominant; cdpx2 Q15125
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (11)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H01194 X-linked chondrodysplasia punctata Q15125 (related)