| class name | count |
|---|---|
| Liliopsida | 43 |
| asterids | 7 |
| class name | count |
|---|---|
| Melanthiaceae | 34 |
| Liliaceae | 9 |
| Solanaceae | 4 |
| Asteraceae | 3 |
| br08003 Category | # of metabolite |
|---|---|
| Steroid alkaloids | 1 |
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Steroid alkaloids | C06543 | C00002261 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00002261
|
Solanidine
|
CHEMBL363703
CHEMBL1534747 CHEMBL1980466 |
C013255
|
5 / 5 / 8 |
|
|
|
C00024019
|
Oblonginine
|
CHEMBL463130
|
|
|||
|
C00027871
|
Anrakorinine
|
|
||||
|
C00028004
|
Camtschatcanidine
|
|
||||
|
C00028250
|
Epi-verazine
|
CHEMBL458682
CHEMBL457588 |
|
|||
|
C00028280
|
Fritillarizine
|
|
||||
|
C00028332
|
Hapepunine
|
|
||||
|
C00028412
|
Isorubijervine
|
|
||||
|
C00028414
|
Iso-shinonomenine
|
|
||||
|
C00028841
|
Pingbeinine
/ (-)-Pingbeinine |
C065749
|
|
|||
|
C00028946
|
Rubijervine
|
CHEMBL1512978
CHEMBL1993702 |
5 / 2 / 3 |
|
||
|
C00028947
|
Rubivirine
|
|
||||
|
C00029011
|
Shinonomenine
|
|
||||
|
C00029029
|
Solaspiralidine
|
|
||||
|
C00029053
|
Stenophylline B
|
C043148
|
|
|||
|
C00029184
|
Veracintine
|
|
||||
|
C00029193
|
Veramarine
|
|
||||
|
C00029194
|
Veramiline
|
CHEMBL463130
|
|
|||
|
C00029197
|
Veramitaline
|
|
||||
|
C00029198
|
Veramivirine
|
|
||||
|
C00029205
|
Verazine
|
CHEMBL458682
CHEMBL457588 |
C052979
|
|
||
|
C00029212
|
Vertaline B
|
C060393
|
|
|||
|
C00049937
|
25beta-Hydroxyverazine
/ (-)-25beta-Hydroxyverazine |
CHEMBL463129
|
|
|||
|
C00049952
|
4beta-Hydroxyverazine
/ (-)-4beta-Hydroxyverazine |
CHEMBL464354
CHEMBL517301 |
|
|||
|
C00050217
|
Sarachine
/ (-)-Sarachine |
CHEMBL464561
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Enzyme | C00002261 | 1 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00028946 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00028946 | 0 / 1 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002261 | 1 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00028946 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00028946 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00028946 | 0 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002261 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00002261 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002261 | 1 / 2 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #302960 | Chondrodysplasia punctata 2, x-linked dominant; cdpx2 |
Q15125
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H01194 | X-linked chondrodysplasia punctata |
Q15125
(related)
|