KCF-S cluster No. 286 (23 metabolites)

Corresponding Phytochemical cluster No. 4

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (23)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
eudicotyledons	76
Magnoliophyta	22
rosids	9
Liliopsida	1

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Cumulative family count

class name	count
Ranunculaceae	25
Papaveraceae	25
Menispermaceae	20
Rutaceae	8
Annonaceae	7
Magnoliaceae	7
Berberidaceae	6
Aristolochiaceae	4
Lauraceae	4
Euphorbiaceae	1
Colchicaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Isoquinoline alkaloids	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Isoquinoline alkaloids	C09581	C00001885

Metabolite list (23)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001885	Escholin / Escholine / Thalictrin / Thalictrine / Magnoflorine / (+)-Magnoflorine	CHEMBL235428	C001670
C00025251	(-)-Sukhodianine beta-N-oxide
C00025667	(+)-Laurifoline	CHEMBL235429
C00025674	N-Methylcorydine / (+)-N-Methylcorydine	CHEMBL1617951
C00025939	Menisperine / (+)-Menisperine / N-Methylisocorydine / (+)-N-Methylisocorydine	CHEMBL175775 CHEMBL1186240	C042421
C00025947	N,N-Dimethyllindcarpine
C00025977	O,O'-Dimethylmagnoflorine
C00026114	Carpoxidine / (-)-Ophiocarpine N-oxide
C00026119	Crebanine N-oxide		C050760
C00027152	N-Methylphoebine
C00027170	Xanthoplanine / (+)-Xanthoplanine	CHEMBL1180065
C00027306	Bulbocapnine beta-N-oxide / (+)-Bulbocapnine beta-N-oxide
C00027370	Fuzitine
C00027382	Isoboldine beta-N-oxide
C00027386	Isocorydine-N-oxide / (+)-Isocorydine N-oxide
C00027390	Isolaureline N-oxide / (-)-Isolaureline N-oxide	CHEMBL1609956		8 / 9 / 3
C00027429	N-Methylnantenine
C00027532	Corydine N-oxide
C00027561	Magnoporphine
C00027588	Preocoteine N-oxide
C00028573	Merenderine N-oxide
C00028700	N-Methylglaucine	CHEMBL1182259
C00028964	Sarcocapnidine N-oxide

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P06746	DNA polymerase beta	Enzyme	C00027390	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00027390	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00027390	2 / 0
O75496	Geminin	Unclassified protein	C00027390	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00027390	7 / 3
Q9UNA4	DNA polymerase iota	Enzyme	C00027390	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00027390	0 / 0
P43351	DNA repair protein RAD52 homolog	Unclassified protein	C00027390	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions