| class name | count |
|---|
| class name | count |
|---|---|
| Streptomycetaceae | 3 |
| Nocardiaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00015612
|
Autolytimycin
/ 19-Demethoxylebstatin |
CHEMBL404493
CHEMBL581969 |
|
|||
|
C00015613
|
19-Demethylreblastatin
|
CHEMBL401784
|
|
|||
|
C00015713
|
Lebstatin
/ Reblastatin / (+)-Reblastatin |
CHEMBL267792
|
|
|||
|
C00018273
|
NSC 330500
/ Macbecin II |
CHEMBL1720432
CHEMBL2001484 |
C025515
|
14 / 18 / 12 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00018273 | 1 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00018273 | 2 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00018273 | 2 / 3 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00018273 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00018273 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00018273 | 4 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00018273 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00018273 | 7 / 3 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00018273 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00018273 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00018273 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00018273 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00018273 | 0 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00018273 | 0 / 3 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00027 | Ovarian cancer |
P38398
(related)
|
| H00031 | Breast cancer |
P38398
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|