KCF-S cluster No. 3072 (3 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Halichondriidae	2
Prorocentraceae	2

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00039897	Okadaic acid	CHEMBL280487 CHEMBL158524 CHEMBL1269053 CHEMBL1454935 CHEMBL1613688 CHEMBL1728497 CHEMBL2006105 CHEMBL2068811 CHEMBL2304065	D019319	18 / 28 / 46	77 / 5
C00045871	DTX-6 / (+)-DTX-6
C00048629	Belizeanic acid / (+)-Belizeanic acid

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00039897	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00039897	7 / 37
Q99700	Ataxin-2	Unclassified protein	C00039897	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00039897	2 / 0
Q15172	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform	Protein phosphatase regulatory subunit	C00039897	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00039897	4 / 2
O75688	Protein phosphatase 1B	Ser_Thr	C00039897	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00039897	2 / 0
O75496	Geminin	Unclassified protein	C00039897	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00039897	7 / 3
P36873	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	Ser_Thr	C00039897	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00039897	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00039897	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00039897	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00039897	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00039897	0 / 0
P67775	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	Ser_Thr	C00039897	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00039897	1 / 0

77 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00039897
226	ALDOA, ALDA, GSD12	aldolase A, fructose-bisphosphate (EC:4.1.2.13)	C00039897
498	ATP5A1, ATP5A, ATP5AL2, ATPM, MC5DN4, MOM2, OMR, ORM, hATP1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	C00039897
513	ATP5D	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit (EC:3.6.1.14)	C00039897
581	BAX, BCL2L4	BCL2-associated X protein	C00039897
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00039897
27101	CACYBP, GIG5, RP1-102G20.6, S100A6BP, SIP	calcyclin binding protein	C00039897
843	CASP10, ALPS2, FLICE2, MCH4	caspase 10, apoptosis-related cysteine peptidase (EC:3.4.22.63)	C00039897
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00039897
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00039897
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00039897
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00039897
8900	CCNA1	cyclin A1	C00039897
9133	CCNB2, HsT17299	cyclin B2	C00039897
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00039897
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00039897
1072	CFL1, CFL	cofilin 1 (non-muscle)	C00039897
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00039897
54927	CHCHD3, MINOS3, PPP1R22	coiled-coil-helix-coiled-coil-helix domain containing 3	C00039897
1139	CHRNA7, CHRNA7-2, NACHRA7	cholinergic receptor, nicotinic, alpha 7 (neuronal)	C00039897
1141	CHRNB2, EFNL3, nAChRB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	C00039897
1207	CLNS1A, CLCI, CLNS1B, ICln	chloride channel, nucleotide-sensitive, 1A	C00039897
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00039897
1387	CREBBP, CBP, KAT3A, RSTS	CREB binding protein (EC:2.3.1.48)	C00039897
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00039897
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00039897
1601	DAB2, DOC-2, DOC2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	C00039897
10521	DDX17, P72, RH70	DEAD (Asp-Glu-Ala-Asp) box helicase 17 (EC:3.6.4.13)	C00039897
11034	DSTN, ACTDP, ADF, bA462D18.2	destrin (actin depolymerizing factor)	C00039897
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00039897
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00039897
2739	GLO1, GLOD1, GLYI	glyoxalase I (EC:4.4.1.5)	C00039897
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00039897
3315	HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27	heat shock 27kDa protein 1	C00039897
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00039897
3717	JAK2, JTK10, THCYT3	Janus kinase 2 (EC:2.7.10.2)	C00039897
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00039897
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00039897
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00039897
5598	MAPK7, BMK1, ERK4, ERK5, PRKM7	mitogen-activated protein kinase 7 (EC:2.7.11.24)	C00039897
4137	MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU	microtubule-associated protein tau	C00039897
5469	MED1, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2	mediator complex subunit 1	C00039897
23184	MESDC2, BOCA, MESD	mesoderm development candidate 2	C00039897
4625	MYH7, CMD1S, CMH1, MPD1, MYHCB, SPMD, SPMM	myosin, heavy chain 7, cardiac muscle, beta	C00039897
54187	NANS, SAS	N-acetylneuraminic acid synthase (EC:2.5.1.56 2.5.1.57)	C00039897
9611	NCOR1, N-CoR, N-CoR1, TRAC1, hN-CoR	nuclear receptor corepressor 1	C00039897
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00039897
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00039897
4830	NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1	NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6)	C00039897
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00039897
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00039897
5093	PCBP1, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X	poly(rC) binding protein 1	C00039897
5110	PCMT1, PIMT	protein-L-isoaspartate (D-aspartate) O-methyltransferase (EC:2.1.1.77)	C00039897
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00039897
5223	PGAM1, PGAM-B, PGAMA	phosphoglycerate mutase 1 (brain) (EC:3.1.3.13 5.4.2.4 5.4.2.11)	C00039897
5241	PGR, NR3C3, PR	progesterone receptor	C00039897
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00039897
5478	PPIA, CYPA, CYPH	peptidylprolyl isomerase A (cyclophilin A) (EC:5.2.1.8)	C00039897
5499	PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A	protein phosphatase 1, catalytic subunit, alpha isozyme (EC:3.1.3.16)	C00039897
5515	PPP2CA, PP2Ac, PP2CA, PP2Calpha, RP-C	protein phosphatase 2, catalytic subunit, alpha isozyme (EC:3.1.3.16)	C00039897
5518	PPP2R1A, PP2A-Aalpha, PP2AAALPHA, PR65A	protein phosphatase 2, regulatory subunit A, alpha (EC:3.1.3.16)	C00039897
25824	PRDX5, ACR1, AOEB166, B166, PLP, PMP20, PRDX6, PRXV, prx-V	peroxiredoxin 5 (EC:1.11.1.15)	C00039897
9588	PRDX6, 1-Cys, AOP2, NSGPx, PRX, aiPLA2, p29	peroxiredoxin 6 (EC:1.11.1.9 1.11.1.15)	C00039897
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00039897
5933	RBL1, CP107, PRB1, p107	retinoblastoma-like 1 (p107)	C00039897
5934	RBL2, P130, Rb2	retinoblastoma-like 2 (p130)	C00039897
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00039897
6206	RPS12, S12	ribosomal protein S12	C00039897
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00039897
6406	SEMG1, CT103, SEMG, SGI, dJ172H20.2	semenogelin I	C00039897
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00039897
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00039897
7018	TF, PRO1557, PRO2086, TFQTL1	transferrin	C00039897
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00039897
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00039897
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00039897
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00039897

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions