KCF-S cluster No. 3485 (3 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	9

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Cumulative family count

class name	count
Bignoniaceae	5
Gesneriaceae	2
Lamiaceae	1
Acanthaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002819	Dunnione	CHEMBL1668320	C474009
C00002836	beta-Lapachone	CHEMBL15192	C014638	53 / 61 / 77	5 / 1
C00041108	Rhinacanthone	CHEMBL512946	C420690

Human Protein / Gene in interactions

53 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002836	1 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00002836	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002836	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00002836	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00002836	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002836	2 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002836	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00002836	2 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002836	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002836	11 / 10
P37840	Alpha-synuclein	Unclassified protein	C00002836	4 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00002836	3 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002836	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00002836	1 / 2
P51570	Galactokinase	Enzyme	C00002836	1 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002836	1 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00002836	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002836	2 / 3
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002836	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002836	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002836	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002836	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002836	2 / 0
O75496	Geminin	Unclassified protein	C00002836	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002836	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00002836	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00002836	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00002836	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00002836	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002836	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00002836	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00002836	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002836	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00002836	5 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002836	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00002836	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002836	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002836	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002836	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002836	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00002836	1 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002836	4 / 3
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00002836	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002836	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002836	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002836	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00002836	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002836	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002836	1 / 1
O00255	Menin	Unclassified protein	C00002836	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002836	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002836	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002836	1 / 4

5 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
10533	ATG7, APG7-LIKE, APG7L, GSA7	autophagy related 7	C00002836
8678	BECN1, ATG6, VPS30, beclin1	beclin 1, autophagy related	C00002836
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00002836
81631	MAP1LC3B, ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a	microtubule-associated protein 1 light chain 3 beta	C00002836
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002836

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions