KCF-S cluster No. 359 (20 metabolites)

Corresponding Phytochemical cluster No. 40

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (20)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Spermatophyta	33
asterids	19
rosids	1

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Cumulative family count

class name	count
Cupressaceae	26
Lamiaceae	19
Podocarpaceae	3
Pinaceae	2
Taxaceae	2
Celastraceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Abietanes	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Abietanes	C09092	C00003426

Metabolite list (20)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003426	Ferruginol	CHEMBL197308
C00031045	Pisiferanol / (+)-Pisiferanol
C00031278	Salvicanol
C00031522	19-Hydroxyferruginol	CHEMBL197310
C00032365	Totaradiol / 3beta-Hydroxytotarol	CHEMBL446064
C00034167	Pomiferin A / (+)-Pomiferin A / 18-Hydroxy-dehydroabietane	CHEMBL12799
C00035987	bietatriene / Dehydroabietane / Abieta-8,11,13-triene
C00036109	Dehydroabietinal	CHEMBL1080038
C00038150	12-Methylferruginol / 12-O-Methylferruginol / (+)-12-Methylferruginol / (+)-12-O-Methylferruginol	CHEMBL226233 CHEMBL226235		1 / 2 / 2
C00038152	12-O-Methylisohinokiol
C00038153	12-O-Methylpisiferanol
C00038205	20-Acetoxypisiferol
C00039446	Isohinokiol	CHEMBL1277661
C00040023	Pisiferal / (+)-Pisiferal
C00040024	Pisiferol	CHEMBL193987
C00040276	Sempervirol	CHEMBL1097038
C00040508	Totarol / (+)-Totarol	CHEMBL487602 CHEMBL1474684 CHEMBL1999971	C078548	20 / 19 / 47
C00044421	12-Hydroxydehydroabietinol	CHEMBL197310
C00048933	16-Hydroxy-ferruginol / (+)-16-Hydroxy-ferruginol
C00049757	Triptobenzene L / (+)-Triptobenzene L

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04637	Cellular tumor antigen p53	Transcription Factor	C00040508	7 / 37
Q99700	Ataxin-2	Unclassified protein	C00040508	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00040508	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00040508	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00040508	2 / 0
O75496	Geminin	Unclassified protein	C00040508	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00040508	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00040508	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00038150	2 / 2
P28482	Mitogen-activated protein kinase 1	Erk	C00040508	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00040508	0 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00040508	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00040508	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00040508	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00040508	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00040508	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00040508	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00040508	1 / 0
O00255	Menin	Unclassified protein	C00040508	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00040508	1 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00040508	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions