KCF-S cluster No. 3762 (3 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Streptomycetaceae	3

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00018664	Mitomycin B	CHEMBL323536
C00018665	NSC 75986 / Mitomycin A	CHEMBL298359	C046000		0 / 1
C00018668	MMC / Mitonco / Mitoplus / Mitocin C / Mutamycin / Ametycine / NSC 26980 / Mitomycin / Mitomycin C	CHEMBL105 CHEMBL518494 CHEMBL1354559 CHEMBL1518783	D016685	113 / 67 / 74	239 / 127

Human Protein / Gene in interactions

113 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00018668	1 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00018668	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00018668	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00018668	1 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00018668	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00018668	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00018668	2 / 2
P08246	Neutrophil elastase	S1A	C00018668	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00018668	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00018668	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00018668	0 / 0
P29466	Caspase-1	C14	C00018668	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00018668	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00018668	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00018668	2 / 2
P00918	Carbonic anhydrase 2	Lyase	C00018668	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00018668	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00018668	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00018668	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00018668	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00018668	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00018668	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00018668	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00018668	0 / 0
P08183	Multidrug resistance protein 1	drug	C00018668	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00018668	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00018668	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00018668	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00018668	0 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00018668	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00018668	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00018668	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00018668	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00018668	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00018668	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00018668	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00018668	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00018668	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00018668	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00018668	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00018668	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00018668	0 / 0
P14902	Indoleamine 2,3-dioxygenase 1	Enzyme	C00018668	0 / 0
P42858	Huntingtin	Unclassified protein	C00018668	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00018668	2 / 0
O75496	Geminin	Unclassified protein	C00018668	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00018668	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00018668	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00018668	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00018668	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00018668	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00018668	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00018668	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00018668	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00018668	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00018668	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00018668	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00018668	0 / 0
P08311	Cathepsin G	S1A	C00018668	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00018668	1 / 0
P03956	Interstitial collagenase	M10A	C00018668	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00018668	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00018668	7 / 3
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00018668	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00018668	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00018668	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00018668	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00018668	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00018668	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00018668	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00018668	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00018668	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00018668	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00018668	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00018668	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00018668	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00018668	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00018668	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00018668	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00018668	0 / 0
P03372	Estrogen receptor	NR3A1	C00018668	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00018668	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00018668	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00018668	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00018668	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00018668	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00018668	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00018668	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00018668	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00018668	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00018668	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00018668	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00018668	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00018668	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00018668	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00018668	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00018668	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00018668	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00018668	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00018668	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00018668	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00018668	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00018668	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00018668	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00018668	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00018668	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00018668	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00018668	1 / 0
O00255	Menin	Unclassified protein	C00018668	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00018668	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00018668	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00018668	1 / 4
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00018668	0 / 3

239 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00018668
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00018668
3983	ABLIM1, ABLIM, LIMAB1, LIMATIN, abLIM-1	actin binding LIM protein 1	C00018668
48	ACO1, ACONS, IREB1, IREBP, IREBP1, IRP1	aconitase 1, soluble (EC:4.2.1.3)	C00018668
10965	ACOT2, CTE-IA, CTE1A, MTE1, PTE2, PTE2A, ZAP128	acyl-CoA thioesterase 2 (EC:3.1.2.2)	C00018668
2180	ACSL1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2	acyl-CoA synthetase long-chain family member 1 (EC:6.2.1.3)	C00018668
2181	ACSL3, ACS3, FACL3, PRO2194	acyl-CoA synthetase long-chain family member 3 (EC:6.2.1.3)	C00018668
10768	AHCYL1, DCAL, IRBIT, PRO0233, XPVKONA	adenosylhomocysteinase-like 1 (EC:3.3.1.1)	C00018668
9590	AKAP12, AKAP250, SSeCKS	A kinase (PRKA) anchor protein 12	C00018668
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00018668
214	ALCAM, CD166, MEMD	activated leukocyte cell adhesion molecule	C00018668
218	ALDH3A1, ALDH3, ALDHIII	aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)	C00018668
316	AOX1, AO, AOH1	aldehyde oxidase 1 (EC:1.2.3.1)	C00018668
327	APEH, AARE, ACPH, APH, D3F15S2, D3S48E, DNF15S2, OPH	acylaminoacyl-peptide hydrolase (EC:3.4.19.1)	C00018668
328	APEX1, APE, APE1, APEN, APEX, APX, HAP1, REF1	APEX nuclease (multifunctional DNA repair enzyme) 1 (EC:4.2.99.18)	C00018668
27350	APOBEC3C, A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C	C00018668
351	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2	amyloid beta (A4) precursor protein	C00018668
427	ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME	N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23)	C00018668
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00018668
476	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)	C00018668
546	ATRX, ATR2, JMS, MRXHF1, RAD54, RAD54L, SFM1, SHS, XH2, XNP, ZNF-HX	alpha thalassemia/mental retardation syndrome X-linked (EC:3.6.4.12)	C00018668
60370	AVPI1, PP5395, RP11-548K23.7, VIP32, VIT32	arginine vasopressin-induced 1	C00018668
25825	BACE2, AEPLC, ALP56, ASP1, ASP21, BAE2, CEAP1, DRAP	beta-site APP-cleaving enzyme 2 (EC:3.4.23.45)	C00018668
572	BAD, BBC2, BCL2L8	BCL2-associated agonist of cell death	C00018668
25805	BAMBI, NMA	BMP and activin membrane-bound inhibitor	C00018668
581	BAX, BCL2L4	BCL2-associated X protein	C00018668
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00018668
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00018668
55909	BIN3	bridging integrator 3	C00018668
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00018668
652	BMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME	bone morphogenetic protein 4	C00018668
93664	CADPS2	Ca++-dependent secretion activator 2	C00018668
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00018668
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00018668
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00018668
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00018668
56267	CCBL2, KAT3, KATIII, RP4-531M19.2	cysteine conjugate-beta lyase 2 (EC:2.6.1.7 4.4.1.13 2.6.1.63)	C00018668
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00018668
891	CCNB1, CCNB	cyclin B1	C00018668
966	CD59, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20	CD59 molecule, complement regulatory protein	C00018668
928	CD9, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29	CD9 molecule	C00018668
978	CDA, CDD	cytidine deaminase (EC:3.5.4.5)	C00018668
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00018668
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00018668
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00018668
9702	CEP57, MVA2, PIG8, TSP57	centrosomal protein 57kDa	C00018668
26511	CHIC2, BTL	cysteine-rich hydrophobic domain 2	C00018668
1159	CKMT1B, CKMT, CKMT1, UMTCK	creatine kinase, mitochondrial 1B (EC:2.7.3.2)	C00018668
1047	CLGN	calmegin	C00018668
1690	COCH, COCH-5B2, COCH5B2, DFNA9, DFNA31	cochlin	C00018668
1284	COL4A2, ICH, POREN2	collagen, type IV, alpha 2	C00018668
1299	COL9A3, DJ885L7.4.1, EDM3, IDD, MED	collagen, type IX, alpha 3	C00018668
10063	COX17	COX17 cytochrome c oxidase copper chaperone	C00018668
1373	CPS1, CPSASE1, PHN	carbamoyl-phosphate synthase 1, mitochondrial (EC:6.3.4.16)	C00018668
10217	CTDSPL, C3orf8, HYA22, PSR1, RBSP3, SCP3	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like (EC:3.1.3.16)	C00018668
1495	CTNNA1, CAP102	catenin (cadherin-associated protein), alpha 1, 102kDa	C00018668
6374	CXCL5, ENA-78, SCYB5	chemokine (C-X-C motif) ligand 5	C00018668
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00018668
64421	DCLRE1C, A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C, hSNM1C	DNA cross-link repair 1C	C00018668
1638	DCT, TRP-2, TYRP2	dopachrome tautomerase (EC:5.3.3.12)	C00018668
1643	DDB2, DDBB, UV-DDB2	damage-specific DNA binding protein 2, 48kDa	C00018668
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00018668
780	DDR1, CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE	discoidin domain receptor tyrosine kinase 1 (EC:2.7.10.1)	C00018668
27122	DKK3, REIC, RIG	dickkopf WNT signaling pathway inhibitor 3	C00018668
1756	DMD, BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272	dystrophin	C00018668
10589	DRAP1, NC2-alpha	DR1-associated protein 1 (negative cofactor 2 alpha)	C00018668
29940	DSE, DSEP, DSEPI, SART-2, SART2	dermatan sulfate epimerase (EC:5.1.3.19)	C00018668
1846	DUSP4, HVH2, MKP-2, MKP2, TYP	dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48)	C00018668
1950	EGF, HOMG4, URG	epidermal growth factor	C00018668
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00018668
9669	EIF5B, IF2	eukaryotic translation initiation factor 5B	C00018668
2004	ELK3, ERP, NET, SAP2	ELK3, ETS-domain protein (SRF accessory protein 2)	C00018668
2013	EMP2, XMP	epithelial membrane protein 2	C00018668
1969	EPHA2, ARCC2, CTPA, CTPP1, CTRCT6, ECK	EPH receptor A2 (EC:2.7.10.1)	C00018668
2065	ERBB3, ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1)	C00018668
405754	ERVFRD-1, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD, UNQ6191, envFRD	endogenous retrovirus group FRD, member 1	C00018668
2149	F2R, CF2R, HTR, PAR-1, PAR1, TR	coagulation factor II (thrombin) receptor	C00018668
116496	FAM129A, C1orf24, NIBAN	family with sequence similarity 129, member A	C00018668
221061	FAM171A1, C10orf38	family with sequence similarity 171, member A1	C00018668
55603	FAM46A, C6orf37, XTP11	family with sequence similarity 46, member A	C00018668
22909	FAN1, KIAA1018, KMIN, MTMR15	FANCD2/FANCI-associated nuclease 1 (EC:3.1.4.1)	C00018668
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00018668
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00018668
2195	FAT1, CDHF7, CDHR8, FAT, ME5, hFat1	FAT atypical cadherin 1	C00018668
2091	FBL, FIB, FLRN, RNU3IP1	fibrillarin	C00018668
2222	FDFT1, DGPT, ERG9, SQS, SS	farnesyl-diphosphate farnesyltransferase 1 (EC:2.5.1.21)	C00018668
2247	FGF2, BFGF, FGF-2, FGFB, HBGF-2	fibroblast growth factor 2 (basic)	C00018668
2273	FHL1, FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA	four and a half LIM domains 1	C00018668
51024	FIS1, TTC11	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	C00018668
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00018668
2534	FYN, SLK, SYN, p59-FYN	FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2)	C00018668
50486	G0S2, RP1-28O10.2	G0/G1switch 2	C00018668
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00018668
2579	GAGE7, AL4, CT4.7, GAGE-7	G antigen 7	C00018668
9289	GPR56, BFPP, TM7LN4, TM7XN1	G protein-coupled receptor 56	C00018668
29899	GPSM2, CMCS, DFNB82, LGN, PINS	G-protein signaling modulator 2	C00018668
2948	GSTM4, GSTM4-4, GTM4	glutathione S-transferase mu 4 (EC:2.5.1.18)	C00018668
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00018668
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00018668
3059	HCLS1, CTTNL, HS1	hematopoietic cell-specific Lyn substrate 1	C00018668
9734	HDAC9, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR	histone deacetylase 9 (EC:3.5.1.98)	C00018668
23462	HEY1, BHLHb31, CHF2, HERP2, HESR1, HRT-1, OAF1, hHRT1	hes-related family bHLH transcription factor with YRPW motif 1	C00018668
3087	HHEX, HEX, HMPH, HOX11L-PEN, PRH, PRHX	hematopoietically expressed homeobox	C00018668
3107	HLA-C, D6S204, HLA-JY3, HLC-C, PSORS1	major histocompatibility complex, class I, C	C00018668
10362	HMG20B, BRAF25, BRAF35, HMGX2, HMGXB2, PP7706, SMARCE1r, SOXL, pp8857	high mobility group 20B	C00018668
3159	HMGA1, HMG-R, HMGA1A, HMGIY	high mobility group AT-hook 1	C00018668
8091	HMGA2, BABL, HMGI-C, HMGIC, LIPO, STQTL9	high mobility group AT-hook 2	C00018668
3312	HSPA8, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, NIP71	heat shock 70kDa protein 8	C00018668
23463	ICMT, HSTE14, MST098, MSTP098, PCCMT, PCMT, PPMT	isoprenylcysteine carboxyl methyltransferase (EC:2.1.1.100)	C00018668
3400	ID4, IDB4, bHLHb27	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	C00018668
3606	IL18, IGIF, IL-18, IL-1g, IL1F4	interleukin 18 (interferon-gamma-inducing factor)	C00018668
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00018668
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00018668
3613	IMPA2	inositol(myo)-1(or 4)-monophosphatase 2 (EC:3.1.3.25)	C00018668
221037	JMJD1C, RP11-10C13.2, TRIP8	jumonji domain containing 1C	C00018668
23189	KANK1, ANKRD15, CPSQ2, KANK	KN motif and ankyrin repeat domains 1	C00018668
23254	KAZN, KAZ	kazrin, periplakin interacting protein	C00018668
9493	KIF23, CHO1, KNSL5, MKLP-1, MKLP1	kinesin family member 23	C00018668
3897	L1CAM, CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1	L1 cell adhesion molecule	C00018668
3958	LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2	lectin, galactoside-binding, soluble, 3	C00018668
3978	LIG1	ligase I, DNA, ATP-dependent (EC:6.5.1.1)	C00018668
22998	LIMCH1, LIMCH1A, LMO7B	LIM and calponin homology domains 1	C00018668
9516	LITAF, PIG7, SIMPLE, TP53I7	lipopolysaccharide-induced TNF factor	C00018668
4000	LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1	lamin A/C	C00018668
4053	LTBP2, C14orf141, GLC3D, LTBP3, MSPKA, MSTP031, WMS3	latent transforming growth factor beta binding protein 2	C00018668
4111	MAGEA12, CT1.12, MAGE12	melanoma antigen family A, 12	C00018668
4102	MAGEA3, CT1.3, HIP8, HYPD, MAGE3, MAGEA6	melanoma antigen family A, 3	C00018668
4105	MAGEA6, CT1.6, MAGE-3b, MAGE3B, MAGE6	melanoma antigen family A, 6	C00018668
4116	MAGOH, MAGOH1, MAGOHA	mago-nashi homolog, proliferation-associated (Drosophila)	C00018668
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00018668
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00018668
9053	MAP7, E-MAP-115, EMAP115	microtubule-associated protein 7	C00018668
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00018668
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00018668
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00018668
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00018668
22919	MAPRE1, EB1	microtubule-associated protein, RP/EB family, member 1	C00018668
4147	MATN2	matrilin 2	C00018668
4155	MBP	myelin basic protein	C00018668
4192	MDK, ARAP, MK, NEGF2	midkine (neurite growth-promoting factor 2)	C00018668
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00018668
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00018668
407040	MIR34A, MIRN34A, miRNA34A, mir-34	microRNA 34a	C00018668
4311	MME, CALLA, CD10, NEP, SFE	membrane metallo-endopeptidase (EC:3.4.24.11)	C00018668
4323	MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS	matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80)	C00018668
5891	MOK, RAGE, RAGE-1, RAGE1	MOK protein kinase (EC:2.7.11.22)	C00018668
4493	MT1E, MT1, MTD	metallothionein 1E	C00018668
4599	MX1, IFI-78K, IFI78, MX, MxA	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	C00018668
29116	MYLIP, IDOL, MIR	myosin regulatory light chain interacting protein (EC:6.3.2.-)	C00018668
4651	MYO10	myosin X	C00018668
4739	NEDD9, CAS-L, CAS2, CASL, CASS2, HEF1	neural precursor cell expressed, developmentally down-regulated 9	C00018668
4800	NFYA, CBF-A, CBF-B, HAP2, NF-YA	nuclear transcription factor Y, alpha	C00018668
9397	NMT2	N-myristoyltransferase 2 (EC:2.3.1.97)	C00018668
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00018668
8204	NRIP1, RIP140	nuclear receptor interacting protein 1	C00018668
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00018668
55872	PBK, CT84, Nori-3, SPK, TOPK	PDZ binding kinase (EC:2.7.12.2)	C00018668
5111	PCNA	proliferating cell nuclear antigen	C00018668
23244	PDS5A, SCC-112, SCC112	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	C00018668
8566	PDXK, C21orf124, C21orf97, PKH, PNK	pyridoxal (pyridoxine, vitamin B6) kinase (EC:2.7.1.35)	C00018668
8544	PIR	pirin (iron-binding nuclear protein) (EC:1.13.11.24)	C00018668
5569	PKIA, PRKACN1	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	C00018668
5328	PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA	plasminogen activator, urokinase (EC:3.4.21.73)	C00018668
5354	PLP1, GPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2	proteolipid protein 1	C00018668
6490	PMEL, D12S53E, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV, gp100	premelanosome protein	C00018668
5376	PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110	peripheral myelin protein 22	C00018668
5447	POR, CPR, CYPOR, P450R	P450 (cytochrome) oxidoreductase (EC:1.6.2.4)	C00018668
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00018668
5590	PRKCZ, PKC-ZETA, PKC2	protein kinase C, zeta (EC:2.7.11.13)	C00018668
5621	PRNP, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30	prion protein	C00018668
23215	PRRC2C, BAT2-iso, BAT2D1, BAT2L2, XTP2	proline-rich coiled-coil 2C	C00018668
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00018668
64284	RAB17	RAB17, member RAS oncogene family	C00018668
55647	RAB20	RAB20, member RAS oncogene family	C00018668
5888	RAD51, BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA	RAD51 recombinase	C00018668
5889	RAD51C, BROVCA3, FANCO, R51H3, RAD51L2	RAD51 paralog C	C00018668
11186	RASSF1, 123F2, NORE2A, RASSF1A, RDA32, REH3P21	Ras association (RalGDS/AF-6) domain family member 1	C00018668
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00018668
5931	RBBP7, RbAp46	retinoblastoma binding protein 7	C00018668
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00018668
5983	RFC3, RFC38	replication factor C (activator 1) 3, 38kDa	C00018668
5984	RFC4, A1, RFC37	replication factor C (activator 1) 4, 37kDa	C00018668
6189	RPS3A, FTE1, MFTL, S3A	ribosomal protein S3A	C00018668
864	RUNX3, AML2, CBFA3, PEBP2aC	runt-related transcription factor 3	C00018668
6281	S100A10, 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10	S100 calcium binding protein A10	C00018668
6282	S100A11, MLN70, S100C	S100 calcium binding protein A11	C00018668
6275	S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98	S100 calcium binding protein A4	C00018668
6303	SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1	spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57)	C00018668
6447	SCG5, 7B2, P7B2, SGNE1, SgV	secretogranin V (7B2 protein)	C00018668
5055	SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	C00018668
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00018668
6446	SGK1, SGK	serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1)	C00018668
9467	SH3BP5, SAB, SH3BP-5	SH3-domain binding protein 5 (BTK-associated)	C00018668
9120	SLC16A6, MCT6, MCT7	solute carrier family 16, member 6	C00018668
6505	SLC1A1, EAAC1, EAAT3, SCZD18	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	C00018668
11000	SLC27A3, ACSVL3, FATP3, VLCS-3	solute carrier family 27 (fatty acid transporter), member 3 (EC:6.2.1.-)	C00018668
10924	SMPDL3A, ASM3A, ASML3a, yR36GH4.1	sphingomyelin phosphodiesterase, acid-like 3A	C00018668
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00018668
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00018668
10580	SORBS1, CAP, FLAF2, R85FL, SH3D5, SH3P12, SORB1	sorbin and SH3 domain containing 1	C00018668
6272	SORT1, Gp95, LDLCQ6, NT3	sortilin 1	C00018668
5552	SRGN, PPG, PRG, PRG1	serglycin	C00018668
6426	SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a	serine/arginine-rich splicing factor 1	C00018668
7982	ST7, ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7	suppression of tumorigenicity 7	C00018668
8614	STC2, STC-2, STCRP	stanniocalcin 2	C00018668
10923	SUB1, P15, PC4, p14	SUB1 homolog (S. cerevisiae)	C00018668
55638	SYBU, GOLSYN, OCSYN, SNPHL	syntabulin (syntaxin-interacting)	C00018668
81550	TDRD3	tudor domain containing 3	C00018668
7020	TFAP2A, AP-2, AP-2alpha, AP2TF, BOFS, TFAP2	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	C00018668
7033	TFF3, ITF, P1B, TFI	trefoil factor 3 (intestinal)	C00018668
7035	TFPI, EPI, LACI, TFI, TFPI1	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	C00018668
7980	TFPI2, PP5, REF1, TFPI-2	tissue factor pathway inhibitor 2	C00018668
23483	TGDS, SDR2E1, TDPGD	TDP-glucose 4,6-dehydratase (EC:4.2.1.46)	C00018668
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00018668
7045	TGFBI, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, LCD1	transforming growth factor, beta-induced, 68kDa	C00018668
7052	TGM2, G-ALPHA-h, GNAH, TG2, TGC	transglutaminase 2 (EC:2.3.2.13)	C00018668
80008	TMEM156	transmembrane protein 156	C00018668
27346	TMEM97, MAC30	transmembrane protein 97	C00018668
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00018668
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00018668
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00018668
7163	TPD52, D52, N8L, PC-1, PrLZ, hD52	tumor protein D52	C00018668
51499	TRIAP1, MDM35, P53CSV, WF-1	TP53 regulated inhibitor of apoptosis 1	C00018668
28951	TRIB2, C5FW, GS3955, TRB2	tribbles pseudokinase 2	C00018668
23321	TRIM2, CMT2R, RNF86	tripartite motif containing 2	C00018668
22059			C00018668
22062			C00018668
1890	TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF	thymidine phosphorylase (EC:2.4.2.4)	C00018668
7298	TYMS, HST422, TMS, TS	thymidylate synthetase (EC:2.1.1.45)	C00018668
5412	UBL3, HCG-1, PNSC1	ubiquitin-like 3	C00018668
7345	UCHL1, NDGOA, PARK5, PGP_9.5, PGP9.5, PGP95, Uch-L1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12)	C00018668
7372	UMPS, OPRT	uridine monophosphate synthetase (EC:2.4.2.10 4.1.1.23)	C00018668
55062	WIPI1, ATG18, ATG18A, WIPI49	WD repeat domain, phosphoinositide interacting 1	C00018668
7474	WNT5A, hWNT5A	wingless-type MMTV integration site family, member 5A	C00018668
9589	WTAP	Wilms tumor 1 associated protein	C00018668
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00018668
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00018668
7518	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	C00018668
23528	ZNF281, ZBP-99, ZNP-99	zinc finger protein 281	C00018668

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