class name | count |
---|---|
asterids | 5 |
class name | count |
---|---|
Lamiaceae | 5 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00031402
![]() |
Tanshinone II
/ Tanshinone IIA |
CHEMBL187266
|
44 / 56 / 79 |
![]() |
||
C00031481
![]() |
1,2-Dihydrotanshinone
|
CHEMBL1813349
|
C028974
|
![]() |
||
C00040078
![]() |
Przewaquinone A
|
CHEMBL578036
|
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00031402 | 7 / 37 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00031402 | 0 / 0 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00031402 | 2 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00031402 | 0 / 0 |
O00748 | Cocaine esterase | Enzyme | C00031402 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00031402 | 11 / 10 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00031402 | 1 / 0 |
P11473 | Vitamin D3 receptor | NR1I1 | C00031402 | 2 / 3 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00031402 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00031402 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00031402 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00031402 | 2 / 0 |
O75496 | Geminin | Unclassified protein | C00031402 | 0 / 0 |
P15121 | Aldose reductase | Enzyme | C00031402 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00031402 | 7 / 3 |
Q9Y253 | DNA polymerase eta | Enzyme | C00031402 | 1 / 1 |
Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00031402 | 0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00031402 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00031402 | 0 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | C00031402 | 0 / 1 |
P06401 | Progesterone receptor | NR3C3 | C00031402 | 0 / 1 |
P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00031402 | 2 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00031402 | 0 / 0 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00031402 | 3 / 3 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00031402 | 2 / 2 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00031402 | 0 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | C00031402 | 1 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00031402 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00031402 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00031402 | 4 / 3 |
O14727 | Apoptotic protease-activating factor 1 | Unclassified protein | C00031402 | 0 / 0 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00031402 | 0 / 0 |
P10275 | Androgen receptor | NR3C4 | C00031402 | 3 / 4 |
P23141 | Liver carboxylesterase 1 | Enzyme | C00031402 | 0 / 0 |
O14746 | Telomerase reverse transcriptase | Enzyme | C00031402 | 5 / 5 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00031402 | 0 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00031402 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00031402 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00031402 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00031402 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00031402 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00031402 | 1 / 2 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00031402 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00031402 | 1 / 4 |
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#609135 | Aplastic anemia |
O14746
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
P18054
P84022 |
#119900 | Digital clubbing, isolated congenital |
P15428
|
#613989 | Dyskeratosis congenita, autosomal dominant, 2; dkca2 |
O14746
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#133239 | Esophageal cancer |
P04637
P18054 |
#600274 | Frontotemporal dementia; ftd |
P10636
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#211980 | Lung cancer |
P04637
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#615134 | Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 |
O14746
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#614742 | Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 |
O14746
|
#178500 | Pulmonary fibrosis, idiopathic; ipf |
O14746
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00764 | Cri du chat syndrome |
O14746
(related)
|
H01132 | Aplastic anemia (AA) |
O14746
(related)
|
H01299 | Idiopathic pulmonary fibrosis |
O14746
(related)
|
H00022 | Bladder cancer |
O14746
(marker)
P04637 (related) |
H00024 | Prostate cancer |
O14746
(marker)
P10275 (related) |
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00026 | Endometrial Cancer |
P04637
(related)
P06401 (marker) |
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
|
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|