KCF-S cluster No. 397 (19 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (19)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Streptomycetaceae	13
Thermomonosporaceae	4
Micromonosporaceae	2

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (19)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00016728	Rubomycin F		C076482
C00016729	NSC 143113 / Rubomycin H / N-Carboxydaunorubicin methyl ester		C076483
C00016816	TAN 1120		C081412
C00018142	Baumycin A1		C015018
C00018143	Baumycin A2
C00018144	Baumycin B1
C00018145	Baumycin B2
C00018146	NSC 227012 / Baumycin C1 / N-Formyldaunorubicin
C00018147	Baumycin C2
C00018317	11-Deoxydoxorubicin		C042239
C00018318	11-Deoxydaunorubicin
C00018343	Feudomycin A / 13-Deoxydaunomycin / 13-Deoxydaunorubicin		C031980
C00018344	Feudomycin B		C031981
C00018351	Rubeomycin A / Antibiotic FA 1180A
C00018352	Rubeomycin A1 / Antibiotic FA 1180A1
C00018353	Rubeomycin B / Antibiotic FA 1180B		C033381
C00018354	Rubeomycin B1 / Antibiotic FA 1180B1
C00018406	4-O-Demethyl-11-deoxydoxorubicin		C034619
C00043440	Daunomycin / Rubomycin C	CHEMBL9659 CHEMBL178 CHEMBL1197788 CHEMBL1525753 CHEMBL1617377	D003630	136 / 91 / 85	121 / 95

Human Protein / Gene in interactions

136 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P14550	Alcohol dehydrogenase [NADP(+)]	Enzyme	C00043440	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00043440	1 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00043440	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00043440	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00043440	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00043440	1 / 1
O95342	Bile salt export pump	drug	C00043440	2 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00043440	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00043440	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00043440	2 / 2
P08246	Neutrophil elastase	S1A	C00043440	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00043440	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00043440	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00043440	0 / 0
P29466	Caspase-1	C14	C00043440	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00043440	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00043440	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00043440	2 / 2
Q13547	Histone deacetylase 1	Hydrolase	C00043440	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00043440	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00043440	3 / 1
P00918	Carbonic anhydrase 2	Lyase	C00043440	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00043440	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00043440	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00043440	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00043440	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00043440	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00043440	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00043440	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00043440	0 / 0
Q9BY41	Histone deacetylase 8	Hydrolase	C00043440	2 / 0
P08183	Multidrug resistance protein 1	drug	C00043440	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00043440	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00043440	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00043440	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00043440	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00043440	1 / 2
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00043440	1 / 8
P11387	DNA topoisomerase 1	Isomerase	C00043440	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00043440	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00043440	2 / 3
P14416	D(2) dopamine receptor	Dopamine receptor	C00043440	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00043440	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00043440	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00043440	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00043440	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00043440	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00043440	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00043440	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00043440	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00043440	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00043440	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00043440	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00043440	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00043440	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00043440	0 / 0
P42858	Huntingtin	Unclassified protein	C00043440	1 / 1
P16152	Carbonyl reductase [NADPH] 1	Enzyme	C00043440	0 / 0
O75496	Geminin	Unclassified protein	C00043440	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00043440	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00043440	4 / 2
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00043440	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00043440	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00043440	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00043440	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00043440	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00043440	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00043440	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00043440	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00043440	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00043440	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00043440	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00043440	0 / 0
P08311	Cathepsin G	S1A	C00043440	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00043440	1 / 0
P03956	Interstitial collagenase	M10A	C00043440	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00043440	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00043440	1 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00043440	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00043440	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00043440	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00043440	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00043440	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00043440	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00043440	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00043440	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00043440	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00043440	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00043440	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00043440	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00043440	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00043440	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00043440	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00043440	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00043440	1 / 3
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00043440	3 / 3
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00043440	2 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00043440	1 / 1
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00043440	0 / 0
P03372	Estrogen receptor	NR3A1	C00043440	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00043440	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00043440	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00043440	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00043440	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00043440	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00043440	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00043440	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00043440	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00043440	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00043440	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00043440	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00043440	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00043440	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00043440	5 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00043440	4 / 3
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00043440	0 / 0
P07477	Trypsin-1	S1A	C00043440	1 / 1
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00043440	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00043440	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00043440	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00043440	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00043440	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00043440	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00043440	0 / 0
Q9UBN7	Histone deacetylase 6	Hydrolase	C00043440	0 / 0
O14746	Telomerase reverse transcriptase	Enzyme	C00043440	5 / 5
Q9UBT6	DNA polymerase kappa	Enzyme	C00043440	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00043440	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00043440	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00043440	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00043440	1 / 1
O00255	Menin	Unclassified protein	C00043440	2 / 5
Q13951	Core-binding factor subunit beta	Unclassified protein	C00043440	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00043440	1 / 4
O95255	Multidrug resistance-associated protein 6	Unclassified protein	C00043440	2 / 1
Q92769	Histone deacetylase 2	Hydrolase	C00043440	0 / 0

121 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00043440
18671			C00043440
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00043440
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00043440
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00043440
25	ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl	c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2)	C00043440
375790	AGRN	agrin	C00043440
10327	AKR1A1, ALDR1, ALR, ARM, DD3	aldo-keto reductase family 1, member A1 (aldehyde reductase) (EC:1.1.1.2)	C00043440
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00043440
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00043440
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00043440
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00043440
63982	ANO3, C11orf25, DYT23, DYT24, TMEM16C	anoctamin 3	C00043440
302	ANXA2, ANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV	annexin A2	C00043440
307	ANXA4, ANX4, PIG28, ZAP36	annexin A4	C00043440
328	APEX1, APE, APE1, APEN, APEX, APX, HAP1, REF1	APEX nuclease (multifunctional DNA repair enzyme) 1 (EC:4.2.99.18)	C00043440
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00043440
580	BARD1	BRCA1 associated RING domain 1	C00043440
581	BAX, BCL2L4	BCL2-associated X protein	C00043440
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00043440
637	BID, FP497	BH3 interacting domain death agonist	C00043440
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00043440
152940	C4orf45	chromosome 4 open reading frame 45	C00043440
51719	CAB39, MO25	calcium binding protein 39	C00043440
779	CACNA1S, CACNL1A3, CCHL1A3, Cav1.1, HOKPP, HOKPP1, MHS5, TTPP1, hypoPP	calcium channel, voltage-dependent, L type, alpha 1S subunit	C00043440
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00043440
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00043440
847	CAT	catalase (EC:1.11.1.6)	C00043440
873	CBR1, CBR, SDR21C1, hCBR1	carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184)	C00043440
874	CBR3, SDR21C2, hCBR3	carbonyl reductase 3 (EC:1.1.1.184)	C00043440
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00043440
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00043440
896	CCND3	cyclin D3	C00043440
898	CCNE1, CCNE	cyclin E1	C00043440
901	CCNG2	cyclin G2	C00043440
993	CDC25A, CDC25A2	cell division cycle 25A (EC:3.1.3.48)	C00043440
1012	CDH13, CDHH, P105	cadherin 13 (EC:3.6.1.3)	C00043440
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00043440
1029	CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16	cyclin-dependent kinase inhibitor 2A	C00043440
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00043440
634	CEACAM1, BGP, BGP1, BGPI	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	C00043440
10153	CEBPZ, CBF, CBF2, HSP-CBF, NOC1	CCAAT/enhancer binding protein (C/EBP), zeta	C00043440
1196	CLK2, hCLK2	CDC-like kinase 2 (EC:2.7.12.1)	C00043440
171425	CLYBL, CLB	citrate lyase beta like	C00043440
56942	CMC2, 2310061C15Rik, C16orf61	C-x(9)-C motif containing 2	C00043440
80790	CMIP, TCMIP	c-Maf inducing protein	C00043440
10283	CWC27, NY-CO-10, SDCCAG10	CWC27 spliceosome-associated protein homolog (S. cerevisiae) (EC:5.2.1.8)	C00043440
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00043440
1676	DFFA, DFF-45, DFF1, ICAD	DNA fragmentation factor, 45kDa, alpha polypeptide	C00043440
1875	E2F5, E2F-5	E2F transcription factor 5, p130-binding	C00043440
1950	EGF, HOMG4, URG	epidermal growth factor	C00043440
9538	EI24, EPG4, PIG8, TP53I8	etoposide induced 2.4	C00043440
1978	EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I	eukaryotic translation initiation factor 4E binding protein 1	C00043440
9852	EPM2AIP1	EPM2A (laforin) interacting protein 1	C00043440
2232	FDXR, ADXR	ferredoxin reductase (EC:1.18.1.6)	C00043440
202309	GAPT, C5orf29	GRB2-binding adaptor protein, transmembrane	C00043440
2262	GPC5	glypican 5	C00043440
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00043440
3184	HNRNPD, AUF1, AUF1A, HNRPD, P37, hnRNPD0	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	C00043440
9641	IKBKE, IKK-E, IKK-i, IKKE, IKKI	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (EC:2.7.11.10)	C00043440
3570	IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80	interleukin 6 receptor	C00043440
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00043440
80895	ILKAP, ILKAP2, ILKAP3, PP2C-DELTA	integrin-linked kinase-associated serine/threonine phosphatase (EC:3.1.3.16)	C00043440
8821	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa (EC:3.1.3.66)	C00043440
547	KIF1A, ATSV, C2orf20, HSN2C, MRD9, SPG30, UNC104	kinesin family member 1A	C00043440
4045	LSAMP, IGLON3, LAMP	limbic system-associated membrane protein	C00043440
338645	LUZP2, KFSP2566, PRO6246	leucine zipper protein 2	C00043440
4131	MAP1B, FUTSCH, MAP5	microtubule-associated protein 1B	C00043440
5606	MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2	mitogen-activated protein kinase kinase 3 (EC:2.7.12.2)	C00043440
4217	MAP3K5, ASK1, MAPKKK5, MEKK5	mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25)	C00043440
4137	MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU	microtubule-associated protein tau	C00043440
4194	MDM4, HDMX, MDMX, MRP1	Mdm4 p53 binding protein homolog (mouse)	C00043440
406991	MIR21, MIRN21, hsa-mir-21, miR-21, miRNA21	microRNA 21	C00043440
2475	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1)	C00043440
8440	NCK2, GRB4, NCKbeta	NCK adaptor protein 2	C00043440
25791	NGEF, ARHGEF27, EPHEXIN	neuronal guanine nucleotide exchange factor	C00043440
4864	NPC1, NPC	Niemann-Pick disease, type C1	C00043440
4879	NPPB, BNP	natriuretic peptide B	C00043440
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00043440
2908	NR3C1, GCCR, GCR, GR, GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	C00043440
4893	NRAS, ALPS4, N-ras, NRAS1, NS6	neuroblastoma RAS viral (v-ras) oncogene homolog	C00043440
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00043440
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00043440
5327	PLAT, T-PA, TPA	plasminogen activator, tissue (EC:3.4.21.68)	C00043440
1263	PLK3, CNK, FNK, PRK	polo-like kinase 3 (EC:2.7.11.21)	C00043440
10848	PPP1R13L, IASPP, NKIP1, RAI, RAI4	protein phosphatase 1, regulatory subunit 13 like	C00043440
9055	PRC1, ASE1	protein regulator of cytokinesis 1	C00043440
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00043440
338095			C00043440
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00043440
64901	RANBP17	RAN binding protein 17	C00043440
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00043440
5929	RBBP5, RBQ3, SWD1	retinoblastoma binding protein 5	C00043440
5930	RBBP6, MY038, P2P-R, PACT, RBQ-1, SNAMA	retinoblastoma binding protein 6	C00043440
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00043440
6198	RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha	ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1)	C00043440
6382	SDC1, CD138, SDC, SYND1, syndecan	syndecan 1	C00043440
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00043440
42601			C00043440
85413	SLC22A16, CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1	solute carrier family 22 (organic cation/carnitine transporter), member 16	C00043440
6586	SLIT3, MEGF5, SLIL2, SLIT1, Slit-3, slit2	slit homolog 3 (Drosophila)	C00043440
6609	SMPD1, ASM, ASMASE, NPD	sphingomyelin phosphodiesterase 1, acid lysosomal (EC:3.1.4.12)	C00043440
55512	SMPD3, NSMASE2	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) (EC:3.1.4.12)	C00043440
3431	SP110, IFI41, IFI75, IPR1, VODI	SP110 nuclear body protein	C00043440
6670	SP3, SPR2	Sp3 transcription factor	C00043440
29114	TAGLN3, NP22, NP24, NP25	transgelin 3	C00043440
6890	TAP1, ABC17, ABCB2, APT1, D6S114E, PSF-1, PSF1, RING4, TAP1*0102N, TAP1N	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	C00043440
6891	TAP2, ABC18, ABCB3, APT2, D6S217E, PSF-2, PSF2, RING11	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	C00043440
30851	TAX1BP3, TIP-1	Tax1 (human T-cell leukemia virus type I) binding protein 3	C00043440
79853	TM4SF20, PRO994, SLI5, TCCE518	transmembrane 4 L six family member 20	C00043440
8797	TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1	tumor necrosis factor receptor superfamily, member 10a	C00043440
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00043440
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00043440
8744	TNFSF9, 4-1BB-L, CD137L	tumor necrosis factor (ligand) superfamily, member 9	C00043440
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00043440
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00043440
11257	TP53TG1, LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1	TP53 target 1 (non-protein coding)	C00043440
7298	TYMS, HST422, TMS, TS	thymidylate synthetase (EC:2.1.1.45)	C00043440
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00043440
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00043440
26137	ZBTB20, DPZF, HOF, ODA-8S, ZNF288	zinc finger and BTB domain containing 20	C00043440

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