class name | count |
---|
class name | count |
---|---|
Micromonosporaceae | 2 |
Streptomycetaceae | 1 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00018638
![]() |
Streptonigrone
|
C045696
|
![]() |
|||
C00026396
![]() |
7-(1-Methyl-2-oxopropyl)streptonigrin
|
CHEMBL447860
|
![]() |
|||
C00026485
![]() |
SN
/ STP / Nigrin / Streptonigrin / Streptonigran / Rufocromomycin |
CHEMBL11417
|
D013308
|
36 / 45 / 37 | 1 / 1 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q16637 | Survival motor neuron protein | Unclassified protein | C00026485 | 4 / 1 |
Q99700 | Ataxin-2 | Unclassified protein | C00026485 | 1 / 1 |
P06746 | DNA polymerase beta | Enzyme | C00026485 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00026485 | 0 / 0 |
Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00026485 | 1 / 4 |
P02545 | Prelamin-A/C | Unclassified protein | C00026485 | 11 / 10 |
P54132 | Bloom syndrome protein | Enzyme | C00026485 | 1 / 2 |
P51570 | Galactokinase | Enzyme | C00026485 | 1 / 1 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00026485 | 1 / 0 |
P11473 | Vitamin D3 receptor | NR1I1 | C00026485 | 2 / 3 |
P39748 | Flap endonuclease 1 | Enzyme | C00026485 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00026485 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00026485 | 2 / 0 |
O75496 | Geminin | Unclassified protein | C00026485 | 0 / 0 |
P51151 | Ras-related protein Rab-9A | Unclassified protein | C00026485 | 0 / 0 |
O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00026485 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00026485 | 7 / 3 |
Q9Y253 | DNA polymerase eta | Enzyme | C00026485 | 1 / 1 |
Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00026485 | 0 / 0 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00026485 | 1 / 2 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00026485 | 0 / 0 |
O15118 | Niemann-Pick C1 protein | Unclassified protein | C00026485 | 1 / 1 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00026485 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00026485 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00026485 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00026485 | 4 / 3 |
Q9UM07 | Protein-arginine deiminase type-4 | Enzyme | C00026485 | 1 / 0 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00026485 | 0 / 0 |
P34949 | Mannose-6-phosphate isomerase | Enzyme | C00026485 | 1 / 1 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00026485 | 0 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00026485 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00026485 | 0 / 0 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00026485 | 1 / 0 |
O00255 | Menin | Unclassified protein | C00026485 | 2 / 5 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00026485 | 2 / 1 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00026485 | 1 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00026485
|
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#208900 | Ataxia-telangiectasia; at |
Q13315
|
#210900 | Bloom syndrome; blm |
P54132
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
P84022
Q14191 |
#602579 | Congenital disorder of glycosylation, type ib; cdg1b |
P34949
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#230200 | Galactokinase deficiency |
P51570
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#180300 | Rheumatoid arthritis; ra |
Q9UM07
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#277700 | Werner syndrome; wrn |
Q14191
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00118 | Congenital disorders of glycosylation (CDG) type I |
P34949
(related)
|
H00070 | Galactosemia |
P51570
(related)
|
H00094 | DNA repair defects |
P54132
(related)
Q13315 (related) |
H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|