KCF-S cluster No. 412 (18 metabolites)
Corresponding Phytochemical cluster No. 38
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 30 |
Cumulative family count
| class name | count |
|---|---|
| Asteraceae | 30 |
KEGG BRITE br08003
Categories (1)
| br08003 Category | # of metabolite |
|---|---|
| Guaianolide | 2 |
metabolites link (2)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Guaianolide | C09288 | C00003206 |
| Guaianolide | C09359 | C00003230 |
Metabolite list (18)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00003206
|
Acroptilin
|
CHEMBL520522
|
|
|||
|
C00003230
|
Centaurepensin
/ Chlorohyssopifolin A |
CHEMBL272221
CHEMBL1334114 |
C027463
|
5 / 9 / 13 |
|
|
|
C00020437
|
Cebellin E
/ Chlororepdiolide |
|
||||
|
C00020438
|
Repensolide
|
|
||||
|
C00020441
|
Chlorohyssopifolin E
|
CHEMBL520862
|
C029802
|
|
||
|
C00020442
|
Chlorohyssopifolin D
|
C029801
|
|
|||
|
C00020443
|
Elegin
/ Linichlorin A / 19-Desoxychlorojanerin |
|
||||
|
C00020444
|
Solstitiolide
|
|
||||
|
C00020445
|
Episolstitiolide
|
|
||||
|
C00020594
|
Desoxyrepin
/ 19-Deoxyjanerin |
|
||||
|
C00020595
|
Janerin
|
CHEMBL485808
|
|
|||
|
C00020736
|
Epoxyrepdiolide
|
|
||||
|
C00020737
|
Repin
|
CHEMBL485807
CHEMBL464878 |
C064339
|
|
||
|
C00020844
|
Linichlorin C
|
|
||||
|
C00020850
|
Acrorepiolide
|
|
||||
|
C00042270
|
Babylin A
|
CHEMBL486401
|
|
|||
|
C00042271
|
Babylin B
|
CHEMBL520536
|
|
|||
|
C00042358
|
Cebellin J
|
CHEMBL520862
|
|
Human Protein / Gene in interactions
5 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11473 | Vitamin D3 receptor | NR1I1 | C00003230 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003230 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003230 | 4 / 3 |
| O00255 | Menin | Unclassified protein | C00003230 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003230 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (13)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|