KCF-S cluster No. 4483 (2 metabolites)

Corresponding Phytochemical cluster No. 25


Plant Species


Cumulative plant class count

class name count
asterids 8
rosids 1

Cumulative family count

class name count
Apiaceae 8
Rutaceae 1

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Furanocoumarins 1

metabolites link (1)

br08003 Category KEGG ID KNApSAcK ID
Furanocoumarins C09283 C00002491

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00002491 External link 512 Peucedanin
CHEMBL1410943
10 / 8 / 6
C00035526 External link 512 Anhydromarmesin
CHEMBL1586775
8 / 5 / 3

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O15118 Niemann-Pick C1 protein Unclassified protein C00002491 C00035526 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002491 C00035526 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00035526 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002491 2 / 0
O75496 Geminin Unclassified protein C00035526 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00035526 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00035526 4 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00035526 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00002491 2 / 2
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002491 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002491 3 / 3
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00002491 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002491 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00035526 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002491 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002491 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#114500 Colorectal cancer; crc P84022
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#257220 Niemann-pick disease, type c1; npc1 O15118
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398

KEGG DISEASE (8)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)