KCF-S cluster No. 47 (79 metabolites)

Corresponding Phytochemical cluster No. 15

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (79)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	102

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Cumulative family count

class name	count
Clusiaceae	39
Fabaceae	33
Moraceae	23
Hypericaceae	5
Calophyllaceae	2

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Xanthenes	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Xanthenes	C10071	C00002958

Metabolite list (79)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002958	1-Isomangostin	CHEMBL481309		1 / 2 / 2
C00009883	Fremontone / 5,7,2',4'-Tetrahydroxy-3'-prenyl-5'-(1''',1'''-dimethylallyl)isoflavone	CHEMBL483415	C061631
C00009917	Lupinisolone C
C00009918	Lupinisoflavone J
C00009920	Lupinisolone B
C00009921	Lupinisoflavone I
C00009931	Lupinisolone A
C00009932	Lupinisoflavone G
C00009933	Lupinisoflavone H
C00009945	Senegalensin	CHEMBL565072
C00009946	Eriotriochin		C064686
C00009950	Euchrenone b10 / 8-Prenylerythrinin C	CHEMBL2159049	C109428	1 / 0 / 0
C00011126	Alvaxanthone	CHEMBL478937
C00011128	8-Prenylxanthone
C00013504	Artonin S / (+)-6,7-Dihydro-3,9-dihydroxy-6-(1-hydroxy-1-methylethyl)-11-methoxy-10-(3-methyl-2-butenyl)-8H-[1]benzopyrano[3,2-d][1]benzoxepin-8-one
C00013535	Broussonol C / 2-[3,4-Dihydroxy-5-(3-methyl-2-butenyl)phenyl]-8,9-dihydro-3,5-dihydroxy-8,9,9-trimethyl-4H-furo[2,3-h]-1-benzopyran-4-one	CHEMBL458761
C00019045	Vogelin G / 4'',5''-Dihydro-5,7-dihydroxy-3'-prenyl-6'',6''-dimethylpyrano[2'',3'':4',5']isoflavone	CHEMBL518341
C00019059	Isosenegalensin / 5,4'-Dihydroxy-5''-(1-hydroxy-1-methylethyl)-6-prenyl-4'',5''-dihydrofurano[2'',3'':7,8]isoflavone	CHEMBL565072
C00019094	Derrisisoflavone F
C00019096	Derrisisoflavone C / 4'-Hydroxy-5-methoxy-5''-(1-hydroxy-1-methylethyl)-6-prenyl-4'',5''-dihydrofurano[2'',3'':7,8]isoflavone
C00019102	Erysenegalensein O / 5,2',4',5''-Tetrahydroxy-6-prenyl-6'',6''-dimethyl-4'',5''-dihydropyrano[2'',3'':7,8]isoflavone
C00019410	Euchretin L / 5,7,5'-Trihydroxy-8-prenyl-6'',6''-dimethyl-4'',5''-dihydropyrano[2'',3'':4',3']coumaronochromone
C00019614	Erythbigenol A / 5,7,4'-Trihydroxy-5'-methoxy-5''-(1-hydroxy-1-methylethyl)-6'-prenyl-4'',5''-dihydrofurano[2'',3'':3',2']isoflavone
C00019615	Erythbigenol B
C00019616	Erythbigenone A / 5,7,4'-Trihydroxy-5'-methoxy-6'-prenyl-6'',6''-dimetyl-4'',5''-dihydropyrano[2'',3'':3',2']isoflavone
C00019617	Erythbigenone B
C00019725	Eryvarin B / 7,4'-Dihydroxy-5''-(1-hydroxy-1-methylethyl)-8'-prenyl-6'',6''-dimethyl-4'',5''-dihydropyrano[2'',3'':5,6]isoflavone
C00019760	Erysenegalensein H / 5,2'4'-Trihydroxy-5''-(1-hydroxy-1-methylethyl)-8-prenyl-4'',5''-dihydrofurano[2'',3'',7,6]isoflavone
C00019761	Erysenegalensein I / 5,2',4'-Trihydroxy-8-prenyl-6'',6''-dimethyl-4'',5''-dihydropyrano[2'',3'':7,6]isoflavone
C00024195	Gerontoxanthone C
C00024197	Gerontoxanthone E
C00024198	Gerontoxanthone G	CHEMBL479107
C00024200	Gerontoxanthone I	CHEMBL478791		11 / 12 / 5
C00029379	11-Hydroxy-1-isomangostin	CHEMBL1080697		2 / 0 / 0
C00030357	Garcinone C
C00030358	Garcinone D	CHEMBL462879		3 / 2 / 2
C00030721	Mangostanin / (-)-Mangostanin	CHEMBL1080698		2 / 0 / 0
C00030722	Mangostanol / (+)-Mangostanol	CHEMBL1224250
C00030723	Mangostenone C / (-)-Mangostenone C
C00030724	Mangostenone D / (-)-Mangostenone D
C00030725	Mangostenone E
C00033514	1,2-Dihydro-1,8,10-trihydroxy-2-(2-hydroxypropan-2-yl)-9-(3-methylbut-2-enyl)furo[3,2-a]-xanthen-11-one
C00033578	6-Deoxy-7-demethylmangostanin / (-)-6-Deoxy-7-demethylmangostanin
C00034764	3-Isomangostin	CHEMBL464119		2 / 0 / 0
C00034776	6-O-Methylmangostanin / (+)-6-O-Methylmangostanin
C00034844	Formoxanthone C
C00034915	Vogelin H / (-)-Vogelin H
C00035281	Cratoxylone
C00035819	Caloxanthone B / (+)-Caloxanthone B
C00036180	Nigrolineaxanthone E	CHEMBL1254295
C00036707	Pinetoxanthone / Allanxanthone A
C00036964	Cudraxanthone E
C00037343	Isorheediaxanthone B
C00037517	Morusignin G / (-)-Morusignin G
C00037729	Rheediaxanthone B / (-)-Rheediaxanthone B
C00037730	Rheediaxanthone C
C00037857	Subelliptenone B
C00037862	Subelliptenone I
C00038875	Cudratricusxanthone A	CHEMBL200640
C00038876	Cudratricusxanthone J	CHEMBL395246
C00038879	Cudratricusxanthone M	CHEMBL397206
C00038880	Cudraxanthone C	CHEMBL200429		2 / 0 / 0
C00038882	Cudraxanthone L	CHEMBL197916		2 / 0 / 0
C00041532	Furowanin B / (+)-Furowanin B	CHEMBL491885		1 / 1 / 1
C00042982	Scortechinone U / (-)-Scortechinone U	CHEMBL486992
C00043726	Millewanin E
C00044663	Cratoxyarborenone D	CHEMBL459106
C00044958	Nigrolineaxanthone J	CHEMBL462456
C00044962	Nigrolineaxanthone N	CHEMBL408716
C00044963	Nigrolineaxanthone O	CHEMBL464127
C00044965	Nigrolineaxanthone Q	CHEMBL467408
C00045813	Cudraxanthone P
C00045815	Cudraxanthone R
C00045961	Garcimangosone C
C00046041	Isoalvaxanthone	CHEMBL517059
C00046804	Macluraxanthone B	CHEMBL370126		2 / 0 / 0
C00046805	Macluraxanthone C	CHEMBL487991
C00047150	7,8]isoflavone / (+)-5,4'-Dihydroxy-6-(3'-methylbut-2''-enyl)-2'''-(4'''-hydroxy-4'''-methylethyl)-3'''-methoxydihydrofurano-[4''',5'''	CHEMBL557289
C00047789	Cathafuran D / (-)-Cathafuran D

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q04206	Transcription factor p65	Transcription Factor	C00029379 C00030358 C00030721 C00034764	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00029379 C00030358 C00030721 C00034764	0 / 0
P35610	Sterol O-acyltransferase 1	Enzyme	C00038880 C00038882 C00046804	0 / 0
O75908	Sterol O-acyltransferase 2	Enzyme	C00038880 C00038882 C00046804	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00002958 C00030358	2 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00024200	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00024200	2 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00024200	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00024200	7 / 3
Q99700	Ataxin-2	Unclassified protein	C00024200	1 / 1
O75496	Geminin	Unclassified protein	C00024200	0 / 0
P03372	Estrogen receptor	NR3A1	C00041532	1 / 1
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00009950	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00024200	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00024200	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00024200	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00024200	1 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00024200	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions