| class name | count |
|---|---|
| asterids | 17 |
| class name | count |
|---|---|
| Rubiaceae | 17 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00031123
|
RA I
|
CHEMBL1288988
|
|
|||
|
C00031124
|
RA II
|
|
||||
|
C00031125
|
RA III
|
CHEMBL539463
|
C045633
|
|
||
|
C00031126
|
RA IV
|
|
||||
|
C00031127
|
RA IX
|
CHEMBL562775
|
|
|||
|
C00031129
|
RA V
|
CHEMBL319656
CHEMBL404613 CHEMBL1475206 CHEMBL1705256 CHEMBL2361311 |
C043547
|
16 / 9 / 9 |
|
|
|
C00031131
|
RA VI
|
CHEMBL539463
|
|
|||
|
C00031132
|
RA VII
|
CHEMBL289601
CHEMBL321199 |
C043548
|
|
||
|
C00031133
|
RA VIII
|
|
||||
|
C00031134
|
RA X
|
CHEMBL554360
|
C079025
|
|
||
|
C00031135
|
RA XI
|
|
||||
|
C00031136
|
RA XII
|
CHEMBL1288990
|
C081563
|
|
||
|
C00031137
|
RA XIII
|
|
||||
|
C00031138
|
RA XIV
|
|
||||
|
C00031139
|
RA-XV
|
|
||||
|
C00031140
|
RA-XVI
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00031129 | 1 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00031129 | 4 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00031129 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00031129 | 0 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00031129 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00031129 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00031129 | 0 / 0 |
| P42226 | Signal transducer and activator of transcription 6 | Unclassified protein | C00031129 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00031129 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00031129 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00031129 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00031129 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00031129 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00031129 | 1 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00031129 | 0 / 3 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | C00031129 | 1 / 2 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| KEGG | name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
Q06710 (related) |
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|