Plant Species

Cumulative plant class count

class name count
Magnoliophyta 4
Embryophyta 1
Spermatophyta 1

Cumulative family count

class name count
Magnoliaceae 4
Herbertaceae 1
Pinaceae 1

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
C00001259 External link 512 Naphthalene
6 / 5 / 4 43 / 18
C00042269 External link 512 Azulene

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
P42574 Caspase-3 C14 C00001259 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00001259 0 / 0
O75496 Geminin Unclassified protein C00001259 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00001259 2 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001259 0 / 0
P10275 Androgen receptor NR3C4 C00001259 3 / 4

43 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC: C00001259
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001259
429 ASCL1, ASH1, HASH1, MASH1, bHLHa46 achaete-scute family bHLH transcription factor 1 C00001259
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00001259
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC: C00001259
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC: C00001259
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC: C00001259
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC: C00001259
1557 CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 cytochrome P450, family 2, subfamily C, polypeptide 19 (EC: C00001259
1558 CYP2C8, CPC8, CYPIIC8, MP-12/MP-20 cytochrome P450, family 2, subfamily C, polypeptide 8 (EC: C00001259
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC: C00001259
1565 CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 cytochrome P450, family 2, subfamily D, polypeptide 6 (EC: C00001259
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00001259
13107 C00001259
29785 CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 (EC: C00001259
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC: C00001259
1577 CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 cytochrome P450, family 3, subfamily A, polypeptide 5 (EC: C00001259
2052 EPHX1, EPHX, EPOX, HYL1, MEH epoxide hydrolase 1, microsomal (xenobiotic) (EC: C00001259
2053 EPHX2, CEH, SEH epoxide hydrolase 2, cytoplasmic (EC: C00001259
2252 FGF7, HBGF-7, KGF fibroblast growth factor 7 C00001259
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00001259
2521 FUS, ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS fused in sarcoma C00001259
2642 GCGR, GGR glucagon receptor C00001259
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC: C00001259
8870 IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1 immediate early response 3 C00001259
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00001259
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00001259
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00001259
3956 LGALS1, GAL1, GBP lectin, galactoside-binding, soluble, 1 C00001259
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00001259
4159 MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL melanocortin 3 receptor C00001259
4160 MC4R melanocortin 4 receptor C00001259
4161 MC5R, MC2 melanocortin 5 receptor C00001259
10403 NDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80 NDC80 kinetochore complex component C00001259
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC: C00001259
5053 PAH, PH, PKU, PKU1 phenylalanine hydroxylase (EC: C00001259
5894 RAF1, CRAF, NS5, Raf-1, c-Raf v-raf-1 murine leukemia viral oncogene homolog 1 (EC: C00001259
389 RHOC, ARH9, ARHC, H9, RHOH9 ras homolog family member C C00001259
7356 SCGB1A1, CC10, CC16, CCPBP, CCSP, UGB, UP-1, UP1 secretoglobin, family 1A, member 1 (uteroglobin) C00001259
6855 SYP, MRXSYP synaptophysin C00001259
6932 TCF7, TCF-1 transcription factor 7 (T-cell specific, HMG-box) C00001259
7076 TIMP1, CLGI, EPA, EPO, HCI, TIMP TIMP metallopeptidase inhibitor 1 C00001259
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00001259

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#114500 Colorectal cancer; crc P18054
#133239 Esophageal cancer P18054
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275


KEGG name UniProt
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)

Diseases related to CTD interactions

18 disease in interactions with metabolites

D000014 Abnormalities, Drug-Induced C00001259
D058186 Acute Kidney Injury C00001259
D055371 Acute Lung Injury C00001259
D000743 Anemia, Hemolytic C00001259
D002386 Cataract C00001259
D006456 Hemoglobinuria C00001259
D006529 Hepatomegaly C00001259
D006959 Hyperoxaluria C00001259
D006965 Hyperplasia C00001259
D008114 Liver Neoplasms, Experimental C00001259
D055370 Lung Injury C00001259
D008175 Lung Neoplasms C00001259
D048629 Micronuclei, Chromosome-Defective C00001259
D009336 Necrosis C00001259
D009362 Neoplasm Metastasis C00001259
D011041 Poisoning C00001259
D014133 Tracheal Diseases C00001259
D015431 Weight Loss C00001259