| class name | count |
|---|---|
| rosids | 13 |
| class name | count |
|---|---|
| Meliaceae | 12 |
| Rutaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00038444
|
Amotsangin G
/ (-)-Amotsangin G |
|
||||
|
C00042996
|
Severinolide
/ (+)-Severinolide |
|
||||
|
C00047632
|
1,3,7-Trideacetylkhivorin
|
CHEMBL1079815
CHEMBL1445173 |
3 / 0 / 1 |
|
||
|
C00047648
|
1-Deacetylkhivorin
|
|
||||
|
C00047659
|
3,7-Dideacetylkhivorin
|
CHEMBL1081405
CHEMBL2332202 |
|
|||
|
C00047661
|
3-Deacetylkhivorin
|
CHEMBL1075818
CHEMBL1447318 CHEMBL2332194 |
5 / 6 / 7 |
|
||
|
C00047689
|
7-Deacetylkhivorin
|
CHEMBL1075851
CHEMBL1395215 |
3 / 0 / 1 |
|
||
|
C00047945
|
Khivorin
|
CHEMBL1075850
CHEMBL1434220 |
3 / 4 / 2 |
|
||
|
C00048944
|
3,7-Dideacetyl khivorin
|
CHEMBL1081405
CHEMBL2332202 |
|
|||
|
C00048946
|
3-Deacetyl khivorin
|
CHEMBL1075818
CHEMBL1447318 CHEMBL2332194 |
5 / 6 / 7 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00047632 C00047661 C00047689 C00047945 C00048946 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00047632 C00047661 C00047689 C00047945 C00048946 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00047661 C00048946 | 2 / 3 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00047661 C00048946 | 4 / 3 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00047661 C00048946 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00047632 C00047689 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00047945 | 4 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|