PCIDB

KCF-S cluster No. 5425 (2 metabolites)

Plant Species

Cumulative plant class count

class name count

Cumulative family count

class name count
Amanitaceae 2
Tricholomataceae 1

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00001422 External link 512 Muscarine
CHEMBL12587
CHEMBL105471
CHEMBL404094
CHEMBL1180201
D009116
12 / 8 / 5 0 / 1
C00027602 External link 512 (-)-allo-Muscarine
CHEMBL12587
CHEMBL105471
CHEMBL404094
CHEMBL1180201
12 / 8 / 5

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001422 C00027602 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001422 C00027602 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001422 C00027602 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00001422 C00027602 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00001422 C00027602 0 / 0
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00001422 C00027602 1 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001422 C00027602 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001422 C00027602 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00001422 C00027602 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001422 C00027602 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001422 C00027602 0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001422 C00027602 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#608516 Major depressive disorder; mdd P08172

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D019966 Substance-Related Disorders C00001422