KCF-S cluster No. 579 (14 metabolites)

Corresponding Phytochemical cluster No. 25

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
asterids	36
rosids	7

---

Cumulative family count

class name	count
Apiaceae	34
Moraceae	5
Rutaceae	2
Asteraceae	2

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Furanocoumarins	1

---

metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Furanocoumarins	C09141	C00002453

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002453	Byakangelicin / (+)-Byakangelicin	CHEMBL508648	C434685	5 / 2 / 0
C00019845	7-(2,3-Dihydroxy-3-methylbutyloxy)-5-hydroxy-5-methoxycoumarin	CHEMBL1574904		8 / 9 / 7
C00019846	7-(2,3-Dihydroxy-3-methylbutyloxy)-5-hydroxy-6-methoxycoumarin
C00029597	8-(3-Chloro-2-hydroxy-3-methylbutoxy)psoralen / (+)-8-(3-Chloro-2-hydroxy-3-methylbutoxy)psoralen
C00030905	Oxypeucedanin hydrate / (+)-Oxypeucedanin hydrate	CHEMBL454060 CHEMBL1438253		13 / 5 / 8
C00032665	5-O-(3-Chloro-2-hydroxy-3-methylbutyl)-8-methoxypsoralen
C00033364	Saxalin
C00035023	5-Methoxy-3-(3-methyl-2,3-dihydroxybutyl)psoralen / (-)-5-Methoxy-3-(3-methyl-2,3-dihydroxybutyl)-psoralen
C00035717	(+)-Oxypeucedanin / Oxypeucedanin hydrate	CHEMBL454060 CHEMBL1438253		13 / 5 / 8
C00036590	5,8-Dimethoxy-3-(3-methyl-2,3-dihydroxybutyl)-psoralen / (-)-5,8-Dimethoxy-3-(3-methyl-2,3-dihydroxybutyl)-psoralen
C00036599	5-Methoxy-8-(1,1-dimethyl-2,3-dihydroxypropyl)-psoralen / (+)-5-Methoxy-8-(1,1-dimethyl-2,3-dihydroxypropyl)-psoralen
C00036625	6-Methoxy-5-(3-methyl-2,3-dihydroxybutyl)-angelicin
C00037262	Heraclenol	CHEMBL1173444	C087805	3 / 0 / 0
C00037677	Pranferol / (-)-Pranferol		C042677

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P56817	Beta-secretase 1	A1A	C00002453 C00030905 C00035717 C00037262	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002453 C00019845 C00030905 C00035717	0 / 0
P06746	DNA polymerase beta	Enzyme	C00019845 C00030905 C00035717	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00019845 C00030905 C00035717	2 / 2
O75496	Geminin	Unclassified protein	C00030905 C00035717 C00037262	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00019845 C00030905 C00035717	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00019845 C00030905 C00035717	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00019845 C00030905 C00035717	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00030905 C00035717	1 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00030905 C00035717	1 / 4
Q13951	Core-binding factor subunit beta	Unclassified protein	C00030905 C00035717	0 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00030905 C00035717	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00030905 C00035717	1 / 1
P04062	Glucosylceramidase	Enzyme	C00019845	6 / 4
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00037262	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002453	1 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002453	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002453	1 / 0
P06280	Alpha-galactosidase A	Enzyme	C00019845	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions