KCF-S cluster No. 5867 (1 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| rosids | 18 |
| asterids | 3 |
| Liliopsida | 1 |
| eudicotyledons | 1 |
Cumulative family count
| class name | count |
|---|---|
| Fabaceae | 17 |
| Solanaceae | 3 |
| Enterobacteriaceae | 1 |
| Poaceae | 1 |
| Brassicaceae | 1 |
| Montiaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001431
|
Spermidine
|
CHEMBL19612
|
D013095
|
26 / 10 / 12 | 5 / 5 |
|
Human Protein / Gene in interactions
26 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001431 | 1 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001431 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00001431 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00001431 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00001431 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001431 | 3 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00001431 | 1 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001431 | 0 / 1 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00001431 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001431 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00001431 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00001431 | 1 / 2 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001431 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00001431 | 0 / 0 |
| Q6QHF9 | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Enzyme | C00001431 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001431 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00001431 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001431 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001431 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001431 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001431 | 0 / 1 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00001431 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00001431 | 1 / 1 |
| P40225 | Thrombopoietin | Unclassified protein | C00001431 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001431 | 0 / 0 |
| Q9H015 | Solute carrier family 22 member 4 | Unclassified protein | C00001431 | 1 / 1 |
5 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 153 | ADRB1, ADRB1R, B1AR, BETA1AR, RHR | adrenoceptor beta 1 |
C00001431
|
| 154 | ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR | adrenoceptor beta 2, surface |
C00001431
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001431
|
| 486 | FXYD2, ATP1G1, HOMG2 | FXYD domain containing ion transport regulator 2 |
C00001431
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00001431
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (10)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #180300 | Rheumatoid arthritis; ra |
Q9H015
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
KEGG DISEASE (12)
| KEGG | name | UniProt |
|---|---|---|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00286 | Crohn's disease |
Q9H015
(related)
|