| class name | count |
|---|---|
| Liliopsida | 36 |
| class name | count |
|---|---|
| Liliaceae | 21 |
| Melanthiaceae | 15 |
| br08003 Category | # of metabolite |
|---|---|
| Steroid alkaloids | 1 |
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Steroid alkaloids | C10811 | C00002253 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00002253
|
Jervine
|
CHEMBL186779
CHEMBL1402135 CHEMBL1717145 CHEMBL1742371 |
C010206
|
11 / 15 / 12 |
|
|
|
C00027659
|
Ebeiensine
/ 11-Deoxo-6-oxo-5alpha,6-dihydrojervine |
C052510
|
|
|||
|
C00027709
|
1-Hydroxy-5,6-dihydrojervine
|
|
||||
|
C00027721
|
23-Isokuroyurinidine
|
|
||||
|
C00028230
|
Peimisine
/ Ebeiensine |
C052510
|
|
|||
|
C00028358
|
Hupehenisine
|
C051421
|
|
|||
|
C00028420
|
Jervinone
|
CHEMBL1989656
|
|
|||
|
C00028440
|
Kuroyurinidine
|
|
||||
|
C00028812
|
Peimisine
/ Ebeiensine |
C052510
|
|
|||
|
C00029142
|
Tortifolisine
/ (-)-Tortifolisine |
|
||||
|
C00029192
|
Veramanine
|
|
||||
|
C00029199
|
Verapatuline
|
|
||||
|
C00029209
|
Verdine
|
|
||||
|
C00029250
|
Yibeissine
|
C076967
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Enzyme | C00002253 | 1 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002253 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002253 | 0 / 1 |
| Q15465 | Sonic hedgehog protein | Unclassified protein | C00002253 | 4 / 5 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002253 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002253 | 1 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002253 | 7 / 3 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002253 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002253 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002253 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002253 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #302960 | Chondrodysplasia punctata 2, x-linked dominant; cdpx2 |
Q15125
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #142945 | Holoprosencephaly 3; hpe3 |
Q15465
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #611638 | Microphthalmia, isolated, with coloboma 5; mcopcb5 |
Q15465
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #174500 | Polydactyly, preaxial ii; ppd2 |
Q15465
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #147250 | Solitary median maxillary central incisor; smmci |
Q15465
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H01194 | X-linked chondrodysplasia punctata |
Q15125
(related)
|
| H00039 | Basal cell carcinoma |
Q15465
(related)
|
| H00267 | Holoprosencephaly (HPE) |
Q15465
(related)
|
| H00652 | Solitary median maxillary central incisor syndrome |
Q15465
(related)
|
| H01027 | Anophthalmia and microphthalmia (A/M) |
Q15465
(related)
|
| H01160 | Schizencephaly |
Q15465
(related)
|