| class name | count |
|---|---|
| rosids | 15 |
| class name | count |
|---|---|
| Rutaceae | 15 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00029988
|
Clauslactone M
|
|
||||
|
C00030242
|
Excavatin E
|
|
||||
|
C00030243
|
Excavatin G
|
|
||||
|
C00032840
|
Clauslactone N
/ (+)-Clauslactone N |
|
||||
|
C00032841
|
Clauslactone O
/ (+)-Clauslactone O |
|
||||
|
C00032842
|
Clauslactone P
/ (-)-Clauslactone P |
|
||||
|
C00035269
|
Clauslactone E
|
CHEMBL488603
|
|
|||
|
C00036005
|
3'',4''-Dihydrocapnolactone
|
|
||||
|
C00039188
|
Excavatin D
/ (+)-Excavatin D |
CHEMBL1348986
|
4 / 13 / 8 |
|
||
|
C00039189
|
Excavatin F
|
|
||||
|
C00039190
|
Excavatin H
|
|
||||
|
C00039191
|
Excavatin I
/ (+)-Excavatin I |
|
||||
|
C00039192
|
Excavatin J
/ (+)-Excavatin J |
CHEMBL470443
|
|
|||
|
C00046676
|
Clauslactone I
/ (+)-Clauslactone I |
CHEMBL470443
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00039188 | 2 / 2 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00039188 | 7 / 3 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00039188 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00039188 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|