KCF-S cluster No. 596 (14 metabolites)

Corresponding Phytochemical cluster No. 38

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	46

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Cumulative family count

class name	count
Asteraceae	46

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Guaianolide	2

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Guaianolide	C09392	C00003247
Guaianolide	C09489	C00003311

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003247	8-Deoxylactucin	CHEMBL365239		3 / 0 / 0
C00003311	Lactucin	CHEMBL521177
C00020576	[3aR-(3aalpha,4alpha,9aalpha,9bbeta)]-4-(Acetyloxy)-3,3a,4,5,9a,9b-hexahydro-9-(hydroxymethyl)-6-methyl-3-methylene-azuleno[4,5-b]furan-2,7-dione
C00020581	9-Oxoisodehydroleucodin
C00020816	Dehydromatricarin A / 11,12-Dehydromatricarin / (+)-Dehydromatricarin A
C00020830	Dehydroleucodin / Lidbeckialactone / 11,13-Dehydroleucodin	CHEMBL441260 CHEMBL189829	C079949	4 / 2 / 2
C00020832	Isodehydroleucodin	CHEMBL441260 CHEMBL189829		4 / 2 / 2
C00020902	3-Chlorodehydroleucodin	CHEMBL370683		3 / 0 / 0
C00020903	3-Hydroxydehydroleucodin
C00020953	Virginolide
C00033592	8-Acetyllactucin
C00033954	Intybulide / (+)-Intybulide
C00034017	Lactucin-15-oxalate
C00034361	11,13-Dehydrodesacetylmatricarin		C073423

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q04206	Transcription factor p65	Transcription Factor	C00003247 C00020830 C00020832 C00020902	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003247 C00020830 C00020832 C00020902	0 / 0
Q00653	Nuclear factor NF-kappa-B p100 subunit	Transcription Factor	C00003247 C00020830 C00020832 C00020902	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00020830 C00020832	2 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions