Plant Species


Cumulative plant class count

class name count
rosids 3

Cumulative family count

class name count
Fagaceae 1
Fabaceae 1
Brassicaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00002868 External link 512 Vitamin K1
/ Phylloquinone
/ Vitamin K1(20)
/ trans-Phylloquinone
CHEMBL1550
CHEMBL520156
CHEMBL2024140
D010837
10 / 3 / 4 11 / 7

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75469 Nuclear receptor subfamily 1 group I member 2 NR1I2 C00002868 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00002868 2 / 3
P14902 Indoleamine 2,3-dioxygenase 1 Enzyme C00002868 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002868 0 / 0
O75496 Geminin Unclassified protein C00002868 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00002868 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00002868 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002868 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002868 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002868 0 / 0

11 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00002868
637 BID, FP497 BH3 interacting domain death agonist C00002868
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00002868
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00002868
8529 CYP4F2, CPF2 cytochrome P450, family 4, subfamily F, polypeptide 2 (EC:1.14.13.30) C00002868
2147 F2, PT, RPRGL2, THPH1 coagulation factor II (thrombin) (EC:3.4.21.5) C00002868
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00002868
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00002868
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00002868
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00002868
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00002868

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (4)

KEGG name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

7 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002114 Calcinosis C00002868
D002543 Cerebral Hemorrhage C00002868
D003875 Drug Eruptions C00002868
D004485 Eczema C00002868
D006406 Hematoma C00002868
D006973 Hypertension C00002868
D012594 Scleroderma, Localized C00002868