| class name | count |
|---|---|
| rosids | 11 |
| class name | count |
|---|---|
| Rutaceae | 6 |
| Simaroubaceae | 3 |
| Chaetomiaceae | 3 |
| Fabaceae | 1 |
| Clusiaceae | 1 |
| Clavicipitaceae | 1 |
| Phaeosphaeriaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00030967
|
Perforamone B
/ (-)-Perforamone B |
CHEMBL2204371
|
|
|||
|
C00030968
|
Perforamone C
/ (-)-Perforamone C |
|
||||
|
C00030974
|
Peucenin-7-methyl ether
|
CHEMBL2164956
|
|
|||
|
C00031668
|
Chaetoquadrin E
/ (+)-Chaetoquadrin E |
|
||||
|
C00031674
|
Chaetoquadrin K
/ (-)-Chaetoquadrin K |
|
||||
|
C00034835
|
Dulcinone
|
|
||||
|
C00035893
|
Umtatin
/ (-)-Umtatin |
CHEMBL2087926
|
|
|||
|
C00036121
|
Heteropeucenin
|
|
||||
|
C00036196
|
Peucenin
|
CHEMBL1415085
|
1 / 2 / 2 |
|
||
|
C00036202
|
Ptaeroxylin
|
CHEMBL1527943
|
7 / 6 / 6 |
|
||
|
C00038304
|
6-Hydroxymethyleugenin
|
CHEMBL464246
|
|
|||
|
C00039177
|
Eugenetin
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00036196 C00036202 | 2 / 2 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00036202 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00036202 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00036202 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00036202 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00036202 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00036202 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|