KCF-S cluster No. 734 (11 metabolites)

Corresponding Phytochemical cluster No. 40

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (11)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
asterids	22
Spermatophyta	2

---

Cumulative family count

class name	count
Lamiaceae	22
Cupressaceae	2

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Abietanes	1

---

metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Abietanes	C09069	C00003410

Metabolite list (11)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003410	Carnosol	CHEMBL218693 CHEMBL1514916	C068623	17 / 17 / 17	12 / 0
C00030193	Epirosmanol	CHEMBL507166
C00031190	Rosmadial / (-)-Rosmadial	CHEMBL494864
C00031191	Rosmanol
C00031495	12,16-Epoxycarnosol	CHEMBL1079367
C00031517	16-Hydroxycarnosol	CHEMBL491307
C00032255	Sugikurojin D / (+)-Sugikurojin D
C00032256	Sugikurojin E / (+)-Sugikurojin E
C00036208	Salviviridinol
C00037344	Isorosmanol	CHEMBL494659 CHEMBL2333536
C00041292	7-Methoxyrosmanol / (+)-7-Methoxyrosmanol	CHEMBL464376 CHEMBL1081338

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q99700	Ataxin-2	Unclassified protein	C00003410	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003410	2 / 0
Q9Y5X4	Photoreceptor-specific nuclear receptor	NR2E3	C00003410	2 / 2
P37840	Alpha-synuclein	Unclassified protein	C00003410	4 / 2
P11473	Vitamin D3 receptor	NR1I1	C00003410	2 / 3
P39748	Flap endonuclease 1	Enzyme	C00003410	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00003410	0 / 0
P11413	Glucose-6-phosphate 1-dehydrogenase	Enzyme	C00003410	1 / 2
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00003410	2 / 0
O75496	Geminin	Unclassified protein	C00003410	0 / 0
P16233	Pancreatic triacylglycerol lipase	Hydrolase	C00003410	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00003410	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00003410	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00003410	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003410	0 / 0
O00255	Menin	Unclassified protein	C00003410	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003410	1 / 2

12 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00003410
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00003410
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00003410
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00003410
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00003410
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00003410
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00003410
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00003410
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00003410
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00003410
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00003410
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00003410

Related Diseases

Diseases related to proteins in ChEMBL interactions