KCF-S cluster No. 764 (11 metabolites)

Corresponding Phytochemical cluster No. 10


Plant Species


Cumulative plant class count

class name count
eudicotyledons 16

Cumulative family count

class name count
Ranunculaceae 16

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Terpenoid alkaloids 1

metabolites link (1)

br08003 Category KEGG ID KNApSAcK ID
Terpenoid alkaloids C08679 C00001635

Metabolite list (11)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001635 External link 512 Deltaline
CHEMBL1378039
CHEMBL1450099
CHEMBL2112845
6 / 2 / 3
C00029016 External link 512 Siwanine A
/ (+)-Siwanine A
C00029017 External link 512 Siwanine B
/ (-)-Siwanine B
C00029018 External link 512 Siwanine C
/ (+)-Siwanine C
/ N-Deethyl-N-methyltatsiensine
C00029019 External link 512 Siwanine D
C00029075 External link 512 Tatsiensine
C067313
C00029693 External link 512 Anthriscifolcine A
/ Anthriscifolcine B acetate
C00029694 External link 512 Anthriscifolcine B
/ Deacetylanthriscifolcine A
C00029695 External link 512 Anthriscifolcine C
C00029696 External link 512 Anthriscifolcine D
/ 10-Hydroxyanthriscifolcine A
/ 14-O-Methylanthriscifolcine C
C00029697 External link 512 Anthriscifolcine E
/ Deacetylanthriscifolcine D
/ 10-Hydroxyanthriscifolcine B

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001635 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001635 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001635 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001635 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001635 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001635 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)