| class name | count |
|---|
| class name | count |
|---|---|
| Streptomycetaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00018697
|
Azan
/ NSC 749 / Guanazol / Guanazolo / Azaguanine / Pathocidin / NSC 223526 / NSC 151069 / Pathocidine / 8-Azaguanine |
CHEMBL374107
|
D001375
|
26 / 32 / 51 | 1 / 0 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00018697 | 1 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00018697 | 7 / 37 |
| Q99700 | Ataxin-2 | Unclassified protein | C00018697 | 1 / 1 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00018697 | 0 / 0 |
| P00492 | Hypoxanthine-guanine phosphoribosyltransferase | Enzyme | C00018697 | 2 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00018697 | 3 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00018697 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00018697 | 0 / 1 |
| P68871 | Hemoglobin subunit beta | Secreted protein | C00018697 | 4 / 4 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00018697 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00018697 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00018697 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00018697 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00018697 | 4 / 2 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00018697 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00018697 | 0 / 0 |
| O75030 | Microphthalmia-associated transcription factor | Unclassified protein | C00018697 | 4 / 4 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00018697 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00018697 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00018697 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00018697 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00018697 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00018697 | 1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00018697 | 0 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00018697 | 0 / 3 |
| P51531 | Probable global transcription activator SNF2L2 | Unclassified protein | C00018697 | 1 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4137 | MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU | microtubule-associated protein tau |
C00018697
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
O75030
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #613985 | Beta-thalassemia |
P68871
|
| #603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #133239 | Esophageal cancer |
P04637
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #140700 | Heinz body anemias |
P68871
|
| #300323 | Kelley-seegmiller syndrome |
P00492
|
| #300322 | Lesch-nyhan syndrome; lns |
P00492
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #614456 | Melanoma, cutaneous malignant, susceptibility to, 8; cmm8 |
O75030
|
| #601358 | Nicolaides-baraitser syndrome; ncbrs |
P51531
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #603903 | Sickle cell anemia |
P68871
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #103500 | Tietz syndrome |
O75030
|
| #193510 | Waardenburg syndrome, type 2a; ws2a |
O75030
|
| KEGG | name | UniProt |
|---|---|---|
| H00038 | Malignant melanoma |
O75030
(related)
O75030 (marker) P04637 (related) |
| H00169 | Ocular albinism |
O75030
(related)
|
| H00759 | Waardenburg syndrome (WS) |
O75030
(related)
|
| H01187 | Tietz syndrome |
O75030
(related)
|
| H00194 | Lesch-Nyhan syndrome |
P00492
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) P68871 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
P68871 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
P38398 (related) |
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
P38398 (related) |
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00228 | Thalassemia |
P68871
(related)
|
| H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|