Plant Species


Cumulative plant class count

class name count

Cumulative family count

class name count
Streptomycetaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00018697 External link 512 Azan
/ NSC 749
/ Guanazol
/ Guanazolo
/ Azaguanine
/ Pathocidin
/ NSC 223526
/ NSC 151069
/ Pathocidine
/ 8-Azaguanine
CHEMBL374107
D001375
26 / 32 / 51 1 / 0

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018697 1 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00018697 7 / 37
Q99700 Ataxin-2 Unclassified protein C00018697 1 / 1
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00018697 0 / 0
P00492 Hypoxanthine-guanine phosphoribosyltransferase Enzyme C00018697 2 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00018697 3 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00018697 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018697 0 / 1
P68871 Hemoglobin subunit beta Secreted protein C00018697 4 / 4
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00018697 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00018697 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00018697 2 / 0
O75496 Geminin Unclassified protein C00018697 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00018697 4 / 2
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00018697 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018697 0 / 0
O75030 Microphthalmia-associated transcription factor Unclassified protein C00018697 4 / 4
P16050 Arachidonate 15-lipoxygenase Enzyme C00018697 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018697 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018697 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00018697 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00018697 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00018697 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00018697 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00018697 0 / 3
P51531 Probable global transcription activator SNF2L2 Unclassified protein C00018697 1 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
4137 MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU microtubule-associated protein tau C00018697

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (32)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness O75030
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#133239 Esophageal cancer P04637
#137800 Glioma susceptibility 1; glm1 O75874
#140700 Heinz body anemias P68871
#300323 Kelley-seegmiller syndrome P00492
#300322 Lesch-nyhan syndrome; lns P00492
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#614456 Melanoma, cutaneous malignant, susceptibility to, 8; cmm8 O75030
#601358 Nicolaides-baraitser syndrome; ncbrs P51531
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#603903 Sickle cell anemia P68871
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#103500 Tietz syndrome O75030
#193510 Waardenburg syndrome, type 2a; ws2a O75030

KEGG DISEASE (51)

KEGG name UniProt
H00038 Malignant melanoma O75030 (related)
O75030 (marker)
P04637 (related)
H00169 Ocular albinism O75030 (related)
H00759 Waardenburg syndrome (WS) O75030 (related)
H01187 Tietz syndrome O75030 (related)
H00194 Lesch-Nyhan syndrome P00492 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
P68871 (marker)
H00022 Bladder cancer P04637 (related)
P68871 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00548 Brunner syndrome P21397 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)