KCF-S cluster No. 8495 (1 metabolites)

Corresponding Phytochemical cluster No. 1


Plant Species


Cumulative plant class count

class name count
rosids 1

Cumulative family count

class name count
Erythroxylaceae 1

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Tropane alkaloids 1

metabolites link (1)

br08003 Category KEGG ID KNApSAcK ID
Tropane alkaloids C10847 C00002280

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00002280 External link 512 Benzoylecgonine
CHEMBL284394
CHEMBL324339
CHEMBL608547
CHEMBL1671895
C005618
6 / 2 / 2 1 / 6

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002280 2 / 2
P39748 Flap endonuclease 1 Enzyme C00002280 0 / 0
O75496 Geminin Unclassified protein C00002280 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002280 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002280 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002280 0 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1066 CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1 carboxylesterase 1 (EC:3.1.1.1 3.1.1.56) C00002280

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#613688 Long qt syndrome 2; lqt2 Q12809
#609620 Short qt syndrome 1; sqt1 Q12809

KEGG DISEASE (2)

KEGG name UniProt
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

6 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D019970 Cocaine-Related Disorders C00002280
D003072 Cognition Disorders C00002280
D009203 Myocardial Infarction C00002280
D011297 Prenatal Exposure Delayed Effects C00002280
D012120 Respiration Disorders C00002280
D012640 Seizures C00002280