KCF-S cluster No. 8642 (1 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (1)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Streptomycetaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (1)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00018192	Ionomycin	CHEMBL501617	D015759	4 / 6 / 6	105 / 0

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11473	Vitamin D3 receptor	NR1I1	C00018192	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00018192	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00018192	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00018192	4 / 3

105 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
60	ACTB, BRWS1, PS1TP5BP1	actin, beta	C00018192
133	ADM, AM	adrenomedullin	C00018192
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00018192
10109	ARPC2, ARC34, PNAS-139, p34-Arc	actin related protein 2/3 complex, subunit 2, 34kDa	C00018192
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00018192
489	ATP2A3, SERCA3	ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8)	C00018192
597	BCL2A1, ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1	BCL2-related protein A1	C00018192
796	CALCA, CALC1, CGRP, CGRP-I, CGRP1, CT, KC	calcitonin-related polypeptide alpha	C00018192
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00018192
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00018192
6356	CCL11, SCYA11	chemokine (C-C motif) ligand 11	C00018192
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00018192
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00018192
6349	CCL3L1, 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MIP1AP, SCYA3L, SCYA3L1	chemokine (C-C motif) ligand 3-like 1	C00018192
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00018192
9560	CCL4L1, AT744.2, CCL4L, LAG-1, LAG1, SCYA4L	chemokine (C-C motif) ligand 4-like 1	C00018192
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00018192
900	CCNG1, CCNG	cyclin G1	C00018192
22948	CCT5, CCT-epsilon, CCTE, TCP-1-epsilon	chaperonin containing TCP1, subunit 5 (epsilon)	C00018192
4345	CD200, MOX1, MOX2, MRC, OX-2	CD200 molecule	C00018192
960	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1	CD44 molecule (Indian blood group)	C00018192
1015	CDH17, CDH16, HPT-1, HPT1	cadherin 17, LI cadherin (liver-intestine)	C00018192
1072	CFL1, CFL	cofilin 1 (non-muscle)	C00018192
1201	CLN3, BTS, JNCL	ceroid-lipofuscinosis, neuronal 3	C00018192
1291	COL6A1, OPLL	collagen, type VI, alpha 1	C00018192
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00018192
1390	CREM, CREM-2, ICER, hCREM-2	cAMP responsive element modulator	C00018192
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00018192
1457	CSNK2A1, CK2A1, CKII, CSNK2A3	casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1)	C00018192
1487	CTBP1, BARS	C-terminal binding protein 1	C00018192
8065	CUL5, VACM-1, VACM1	cullin 5	C00018192
1806	DPYD, DHP, DHPDHASE, DPD	dihydropyrimidine dehydrogenase (EC:1.3.1.2)	C00018192
1846	DUSP4, HVH2, MKP-2, MKP2, TYP	dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48)	C00018192
1950	EGF, HOMG4, URG	epidermal growth factor	C00018192
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00018192
1959	EGR2, AT591, CMT1D, CMT4E, KROX20	early growth response 2	C00018192
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00018192
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00018192
2355	FOSL2, FRA2	FOS-like antigen 2	C00018192
2533	FYB, ADAP, PRO0823, SLAP-130	FYN binding protein	C00018192
2675	GFRA2, GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2	GDNF family receptor alpha 2	C00018192
2688	GH1, GH, GH-N, GHN, IGHD1B, hGH-N	growth hormone 1	C00018192
10578	GNLY, 519, D2S69E, LAG-2, LAG2, NKG5, TLA519	granulysin	C00018192
3030	HADHA, ECHA, GBP, HADH, LCEH, LCHAD, MTPA, TP-ALPHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)	C00018192
3035	HARS, HRS, USH3B	histidyl-tRNA synthetase (EC:6.1.1.21)	C00018192
3055	HCK, JTK9, p59Hck, p61Hck	hemopoietic cell kinase (EC:2.7.10.2)	C00018192
3074	HEXB, ENC-1AS	hexosaminidase B (beta polypeptide) (EC:3.2.1.52)	C00018192
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00018192
3312	HSPA8, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, NIP71	heat shock 70kDa protein 8	C00018192
3458	IFNG, IFG, IFI	interferon, gamma	C00018192
3460	IFNGR2, AF-1, IFGR2, IFNGT1	interferon gamma receptor 2 (interferon gamma transducer 1)	C00018192
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00018192
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00018192
3558	IL2, IL-2, TCGF, lymphokine	interleukin 2	C00018192
3559	IL2RA, CD25, IDDM10, IL2R, TCGFR	interleukin 2 receptor, alpha	C00018192
3560	IL2RB, CD122, IL15RB, P70-75	interleukin 2 receptor, beta	C00018192
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00018192
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00018192
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00018192
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00018192
3662	IRF4, LSIRF, MUM1, NF-EM5	interferon regulatory factor 4	C00018192
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00018192
3783	KCNN4, IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	C00018192
9314	KLF4, EZF, GKLF	Kruppel-like factor 4 (gut)	C00018192
1316	KLF6, BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9	Kruppel-like factor 6	C00018192
3845	KRAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2	Kirsten rat sarcoma viral oncogene homolog	C00018192
3936	LCP1, CP64, L-PLASTIN, LC64P, LPL, PLS2	lymphocyte cytosolic protein 1 (L-plastin)	C00018192
8425	LTBP4, ARCL1C, LTBP-4, LTBP4L, LTBP4S	latent transforming growth factor beta binding protein 4	C00018192
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00018192
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00018192
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00018192
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00018192
24142	NAT6, FUS-2, FUS2	N-acetyltransferase 6 (GCN5-related) (EC:2.3.1.-)	C00018192
4745	NELL1, IDH3GL, NRP1	NEL-like 1 (chicken)	C00018192
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00018192
4818	NKG7, GIG1, GMP-17, p15-TIA-1	natural killer cell group 7 sequence	C00018192
9111	NMI	N-myc (and STAT) interactor	C00018192
4854	NOTCH3, CADASIL, CASIL, IMF2	notch 3	C00018192
8013	NR4A3, CHN, CSMF, MINOR, NOR1, TEC	nuclear receptor subfamily 4, group A, member 3	C00018192
5338	PLD2	phospholipase D2 (EC:3.1.4.4)	C00018192
8228	PNPLA4, DXS1283E, GS2, iPLA2eta	patatin-like phospholipase domain containing 4 (EC:3.1.1.3)	C00018192
5451	POU2F1, OCT1, OTF1, oct-1B	POU class 2 homeobox 1	C00018192
5452	POU2F2, OCT2, OTF2, Oct-2	POU class 2 homeobox 2	C00018192
5588	PRKCQ, PRKCT, nPKC-theta	protein kinase C, theta (EC:2.7.11.13)	C00018192
1827	RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1	regulator of calcineurin 1	C00018192
5966	REL, C-Rel	v-rel avian reticuloendotheliosis viral oncogene homolog	C00018192
391	RHOG, ARHG	ras homolog family member G	C00018192
8635	RNASET2, RNASE6PL, bA514O12.3	ribonuclease T2 (EC:3.1.27.1)	C00018192
9092	SART1, Ara1, HOMS1, SART1259, SNRNP110, Snu66	squamous cell carcinoma antigen recognized by T cells	C00018192
10262	SF3B4, AFD1, Hsh49, SAP49, SF3b49	splicing factor 3b, subunit 4, 49kDa	C00018192
6503	SLA, SLA1, SLAP	Src-like-adaptor	C00018192
7922	SLC39A7, D6S115E, D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7	solute carrier family 39 (zinc transporter), member 7	C00018192
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00018192
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00018192
6734	SRPR, DP, Sralpha	signal recognition particle receptor (docking protein)	C00018192
6786	STIM1, D11S4896E, GOK, IMD10, TAM	stromal interaction molecule 1	C00018192
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00018192
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00018192
7133	TNFRSF1B, CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR	tumor necrosis factor receptor superfamily, member 1B	C00018192
8744	TNFSF9, 4-1BB-L, CD137L	tumor necrosis factor (ligand) superfamily, member 9	C00018192
7185	TRAF1, EBI6, MGC:10353	TNF receptor-associated factor 1	C00018192
28951	TRIB2, C5FW, GS3955, TRB2	tribbles pseudokinase 2	C00018192
7442	TRPV1, VR1	transient receptor potential cation channel, subfamily V, member 1	C00018192
7305	TYROBP, DAP12, KARAP, PLOSL	TYRO protein tyrosine kinase binding protein	C00018192
7431	VIM, CTRCT30	vimentin	C00018192

Related Diseases

Diseases related to proteins in ChEMBL interactions