KCF-S cluster No. 8774 (1 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (1)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
rosids	4
Magnoliophyta	1

---

Cumulative family count

class name	count
Rosaceae	1
Brassicaceae	1
Rutaceae	1
Piperaceae	1
Elaeagnaceae	1

KEGG BRITE br08003

---

Categories (0)

br08003 Category	# of metabolite

---

metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (1)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001179	Vitamin C / L-Ascorbate / L-Ascorbic acid / (+)-Ascorbic acid	CHEMBL196 CHEMBL1161421	D001205	104 / 58 / 50	254 / 98

Human Protein / Gene in interactions

104 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001179	1 / 0
Q9H6Z9	Egl nine homolog 3	Enzyme	C00001179	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001179	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00001179	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00001179	2 / 2
P08246	Neutrophil elastase	S1A	C00001179	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00001179	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00001179	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00001179	0 / 0
P04746	Pancreatic alpha-amylase	Hydrolase	C00001179	0 / 0
P29466	Caspase-1	C14	C00001179	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00001179	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00001179	0 / 0
Q9UGH3	Solute carrier family 23 member 2	Ascorbate	C00001179	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00001179	2 / 2
P02545	Prelamin-A/C	Unclassified protein	C00001179	11 / 10
P00918	Carbonic anhydrase 2	Lyase	C00001179	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00001179	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00001179	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00001179	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00001179	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00001179	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00001179	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00001179	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00001179	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00001179	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00001179	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00001179	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001179	0 / 1
Q9GZT9	Egl nine homolog 1	Enzyme	C00001179	1 / 1
P13674	Prolyl 4-hydroxylase subunit alpha-1	Enzyme	C00001179	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00001179	1 / 8
P11473	Vitamin D3 receptor	NR1I1	C00001179	2 / 3
P14416	D(2) dopamine receptor	Dopamine receptor	C00001179	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00001179	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00001179	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00001179	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00001179	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00001179	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00001179	0 / 0
Q96KS0	Egl nine homolog 2	Enzyme	C00001179	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00001179	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00001179	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00001179	1 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00001179	0 / 0
Q9NWT6	Hypoxia-inducible factor 1-alpha inhibitor	Enzyme	C00001179	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00001179	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00001179	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00001179	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00001179	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00001179	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00001179	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00001179	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00001179	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00001179	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00001179	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00001179	1 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00001179	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00001179	0 / 0
P08311	Cathepsin G	S1A	C00001179	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00001179	1 / 0
P03956	Interstitial collagenase	M10A	C00001179	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00001179	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00001179	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00001179	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00001179	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00001179	4 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00001179	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00001179	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00001179	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00001179	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00001179	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00001179	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00001179	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00001179	0 / 0
P04745	Alpha-amylase 1	Enzyme	C00001179	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00001179	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00001179	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00001179	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001179	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00001179	0 / 0
P03372	Estrogen receptor	NR3A1	C00001179	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00001179	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00001179	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001179	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001179	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001179	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00001179	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00001179	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00001179	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00001179	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001179	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001179	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00001179	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001179	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001179	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001179	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00001179	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00001179	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00001179	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00001179	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00001179	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00001179	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00001179	0 / 0

254 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
16	AARS, CMT2N	alanyl-tRNA synthetase (EC:6.1.1.7)	C00001179
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00001179
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00001179
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00001179
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00001179
59272	ACE2, ACEH	angiotensin I converting enzyme 2 (EC:3.4.17.23)	C00001179
59	ACTA2, AAT6, ACTSA, MYMY5	actin, alpha 2, smooth muscle, aorta	C00001179
112	ADCY6, AC6	adenylate cyclase 6 (EC:4.6.1.1)	C00001179
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00001179
248	ALPI, IAP	alkaline phosphatase, intestinal (EC:3.1.3.1)	C00001179
290	ANPEP, APN, CD13, GP150, LAP1, P150, PEPN	alanyl (membrane) aminopeptidase (EC:3.4.11.2)	C00001179
301	ANXA1, ANX1, LPC1	annexin A1	C00001179
335	APOA1	apolipoprotein A-I	C00001179
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00001179
55937	APOM, G3a, HSPC336, NG20, apo-M	apolipoprotein M	C00001179
351	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2	amyloid beta (A4) precursor protein	C00001179
360	AQP3, AQP-3, GIL	aquaporin 3 (Gill blood group)	C00001179
397	ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2	Rho GDP dissociation inhibitor (GDI) beta	C00001179
440	ASNS, TS11	asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4)	C00001179
467	ATF3	activating transcription factor 3	C00001179
9212	AURKB, AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5, aurkb-sv1, aurkb-sv2	aurora kinase B (EC:2.7.11.1)	C00001179
581	BAX, BCL2L4	BCL2-associated X protein	C00001179
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00001179
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00001179
79370	BCL2L14, BCLG	BCL2-like 14 (apoptosis facilitator)	C00001179
632	BGLAP, BGP, OC, OCN	bone gamma-carboxyglutamate (gla) protein	C00001179
12095			C00001179
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00001179
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00001179
699	BUB1, BUB1A, BUB1L, hBUB1	BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1)	C00001179
768	CA9, CAIX, MN	carbonic anhydrase IX (EC:4.2.1.1)	C00001179
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001179
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00001179
847	CAT	catalase (EC:1.11.1.6)	C00001179
875	CBS, HIP4	cystathionine-beta-synthase (EC:4.2.1.22)	C00001179
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00001179
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00001179
894	CCND2, KIAK0002	cyclin D2	C00001179
100133941	CD24, CD24A	CD24 molecule	C00001179
947	CD34	CD34 molecule	C00001179
958	CD40, Bp50, CDW40, TNFRSF5, p50	CD40 molecule, TNF receptor superfamily member 5	C00001179
990	CDC6, CDC18L, HsCDC18, HsCDC6	cell division cycle 6	C00001179
728642	CDK11A, CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA	cyclin-dependent kinase 11A (EC:2.7.11.22)	C00001179
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00001179
629	CFB, AHUS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2	complement factor B (EC:3.4.21.47)	C00001179
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00001179
11113	CIT, CRIK, STK21	citron (rho-interacting, serine/threonine kinase 21) (EC:2.7.11.1)	C00001179
1264	CNN1, SMCC, Sm-Calp	calponin 1, basic, smooth muscle	C00001179
1270	CNTF, HCNTF	ciliary neurotrophic factor	C00001179
1277	COL1A1, OI4	collagen, type I, alpha 1	C00001179
1380	CR2, C3DR, CD21, CR, CVID7, SLEB9	complement component (3d/Epstein Barr virus) receptor 2	C00001179
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00001179
1519	CTSO, CTSO1	cathepsin O (EC:3.4.22.42)	C00001179
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00001179
6372	CXCL6, CKA-3, GCP-2, GCP2, SCYB6	chemokine (C-X-C motif) ligand 6	C00001179
4283	CXCL9, CMK, Humig, MIG, SCYB9, crg-10	chemokine (C-X-C motif) ligand 9	C00001179
643	CXCR5, BLR1, CD185, MDR15	chemokine (C-X-C motif) receptor 5	C00001179
79901	CYBRD1, CYB561A2, DCYTB, FRRS3	cytochrome b reductase 1	C00001179
1583	CYP11A1, CYP11A, CYPXIA1, P450SCC	cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6)	C00001179
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001179
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001179
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00001179
1556	CYP2B7P, CYP2B, CYP2B7, CYP2B7P1	cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene	C00001179
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001179
22943	DKK1, DKK-1, SK	dickkopf WNT signaling pathway inhibitor 1	C00001179
9787	DLGAP5, DLG7, HURP	discs, large (Drosophila) homolog-associated protein 5	C00001179
54431	DNAJC10, ERdj5, JPDI, MTHr, PDIA19	DnaJ (Hsp40) homolog, subfamily C, member 10	C00001179
1773	DNASE1, DNL1, DRNI	deoxyribonuclease I (EC:3.1.21.1)	C00001179
1803	DPP4, ADABP, ADCP2, CD26, DPPIV, TP103	dipeptidyl-peptidase 4 (EC:3.4.14.5)	C00001179
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00001179
1908	EDN3, ET-3, ET3, HSCR4, PPET3, WS4B	endothelin 3	C00001179
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00001179
112399	EGLN3, HIFP4H3, HIFPH3, PHD3	egl-9 family hypoxia-inducible factor 3 (EC:1.14.11.29)	C00001179
8894	EIF2S2, EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	C00001179
8661	EIF3A, EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185	eukaryotic translation initiation factor 3, subunit A	C00001179
8343525			C00001179
1973	EIF4A1, DDX2A, EIF-4A, EIF4A, eIF-4A-I, eIF4A-I	eukaryotic translation initiation factor 4A1 (EC:3.6.4.13)	C00001179
2012	EMP1, CL-20, EMP-1, TMP	epithelial membrane protein 1	C00001179
2014	EMP3, YMP	epithelial membrane protein 3	C00001179
2034	EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73	endothelial PAS domain protein 1	C00001179
2052	EPHX1, EPHX, EPOX, HYL1, MEH	epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9)	C00001179
2053	EPHX2, CEH, SEH	epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76)	C00001179
2058	EPRS, EARS, GLUPRORS, PARS, QARS, QPRS	glutamyl-prolyl-tRNA synthetase (EC:6.1.1.15 6.1.1.17)	C00001179
2172	FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP	fatty acid binding protein 6, ileal	C00001179
2321	FLT1, FLT, FLT-1, VEGFR-1, VEGFR1	fms-related tyrosine kinase 1 (EC:2.7.10.1)	C00001179
2326	FMO1	flavin containing monooxygenase 1 (EC:1.14.13.8)	C00001179
2330	FMO5	flavin containing monooxygenase 5 (EC:1.14.13.8)	C00001179
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00001179
2302	FOXJ1, FKHL13, HFH-4, HFH4	forkhead box J1	C00001179
2534	FYN, SLK, SYN, p59-FYN	FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2)	C00001179
2535	FZD2, Fz2, fz-2, fzE2, hFz2	frizzled family receptor 2	C00001179
50486	G0S2, RP1-28O10.2	G0/G1switch 2	C00001179
2580	GAK, DNAJ26, DNAJC26	cyclin G associated kinase (EC:2.7.11.1)	C00001179
2617	GARS, CMT2D, DSMAV, GlyRS, HMN5, SMAD1	glycyl-tRNA synthetase (EC:6.1.1.14)	C00001179
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00001179
2674	GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1	GDNF family receptor alpha 1	C00001179
2744	GLS, AAD20, GAC, GAM, GLS1, KGA	glutaminase (EC:3.5.1.2)	C00001179
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00001179
2877	GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2	glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9)	C00001179
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00001179
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00001179
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00001179
2952	GSTT1	glutathione S-transferase theta 1 (EC:2.5.1.18)	C00001179
2965	GTF2H1, BTF2, P62, TFB1, TFIIH	general transcription factor IIH, polypeptide 1, 62kDa	C00001179
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00001179
9843	HEPH, CPL	hephaestin	C00001179
9709	HERPUD1, HERP, Mif1, SUP	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	C00001179
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00001179
3098	HK1, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1	hexokinase 1 (EC:2.7.1.1)	C00001179
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00001179
3240	HP, BP, HP2ALPHA2, HPA1S	haptoglobin	C00001179
3283	HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1)	C00001179
3303	HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1	heat shock 70kDa protein 1A	C00001179
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00001179
3313	HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74	heat shock 70kDa protein 9 (mortalin)	C00001179
3315	HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27	heat shock 27kDa protein 1	C00001179
3347	HTN3, HIS2, HTN2, HTN5	histatin 3	C00001179
3376	IARS, IARS1, ILERS, ILRS, IRS, PRO0785	isoleucyl-tRNA synthetase (EC:6.1.1.5)	C00001179
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00001179
8870	IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1	immediate early response 3	C00001179
3488	IGFBP5, IBP5	insulin-like growth factor binding protein 5	C00001179
10320	IKZF1, Hs.54452, IK1, IKAROS, LYF1, PRO0758, ZNFN1A1, hIk-1	IKAROS family zinc finger 1 (Ikaros)	C00001179
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00001179
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001179
3745	KCNB1, DRK1, KV2.1, h-DRK1	potassium voltage-gated channel, Shab-related subfamily, member 1	C00001179
3791	KDR, CD309, FLK1, VEGFR, VEGFR2	kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1)	C00001179
9493	KIF23, CHO1, KNSL5, MKLP-1, MKLP1	kinesin family member 23	C00001179
3932	LCK, LSK, YT16, p56lck, pp58lck	lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2)	C00001179
3956	LGALS1, GAL1, GBP	lectin, galactoside-binding, soluble, 1	C00001179
4017	LOXL2, LOR2, WS9-14	lysyl oxidase-like 2 (EC:1.4.3.-)	C00001179
4067	LYN, JTK8, p53Lyn, p56Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2)	C00001179
23764	MAFF, U-MAF, hMafF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	C00001179
10892	MALT1, IMD12, MLT, MLT1	mucosa associated lymphoid tissue lymphoma translocation gene 1 (EC:3.4.22.-)	C00001179
5606	MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2	mitogen-activated protein kinase kinase 3 (EC:2.7.12.2)	C00001179
5608	MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3	mitogen-activated protein kinase kinase 6 (EC:2.7.12.2)	C00001179
4217	MAP3K5, ASK1, MAPKKK5, MEKK5	mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25)	C00001179
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00001179
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00001179
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00001179
4173	MCM4, CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21	minichromosome maintenance complex component 4 (EC:3.6.4.12)	C00001179
4224	MEP1A, PPHA	meprin A, alpha (PABA peptide hydrolase) (EC:3.4.24.18)	C00001179
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00001179
4288	MKI67, KIA, MIB-1	marker of proliferation Ki-67	C00001179
4292	MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1	mutL homolog 1	C00001179
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00001179
4316	MMP7, MMP-7, MPSL1, PUMP-1	matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23)	C00001179
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00001179
4436	MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2	mutS homolog 2	C00001179
4485	MST1, D3F15S2, DNF15S2, HGFL, MSP, NF15S2	macrophage stimulating 1 (hepatocyte growth factor-like)	C00001179
11223	MST1L, BRF-1, D1F15S1A, MSPL-7, MSPL7, MST1P9, MSTP7, MSTP9	macrophage stimulating 1-like	C00001179
4504	MT3, GIF, GIFB, GRIF, ZnMT3	metallothionein 3	C00001179
10797	MTHFD2, NMDMC	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15)	C00001179
4605	MYBL2, B-MYB, BMYB	v-myb avian myeloblastosis viral oncogene homolog-like 2	C00001179
4640	MYO1A, BBMI, DFNA48, MIHC, MYHL	myosin IA	C00001179
4677	NARS, ASNRS, NARS1	asparaginyl-tRNA synthetase (EC:6.1.1.22)	C00001179
10397	NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5	N-myc downstream regulated 1	C00001179
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00001179
4800	NFYA, CBF-A, CBF-B, HAP2, NF-YA	nuclear transcription factor Y, alpha	C00001179
4814	NINJ1, NIN1, NINJURIN	ninjurin 1	C00001179
7080	NKX2-1, BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1	NK2 homeobox 1	C00001179
4830	NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1	NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6)	C00001179
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001179
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00001179
2908	NR3C1, GCCR, GCR, GR, GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	C00001179
8013	NR4A3, CHN, CSMF, MINOR, NOR1, TEC	nuclear receptor subfamily 4, group A, member 3	C00001179
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00001179
10956	OS9, ERLEC2, OS-9	osteosarcoma amplified 9, endoplasmic reticulum lectin	C00001179
8974	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II (EC:1.14.11.2)	C00001179
54681	P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	C00001179
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001179
5106	PCK2, PEPCK, PEPCK-M, PEPCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32)	C00001179
64714	PDIA2, PDA2, PDI, PDIP, PDIR	protein disulfide isomerase family A, member 2 (EC:5.3.4.1)	C00001179
2923	PDIA3, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC	protein disulfide isomerase family A, member 3 (EC:5.3.4.1)	C00001179
26227	PHGDH, 3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA	phosphoglycerate dehydrogenase (EC:1.1.1.95)	C00001179
22822	PHLDA1, DT1P1B11, PHRIP, TDAG51	pleckstrin homology-like domain, family A, member 1	C00001179
7262	PHLDA2, BRW1C, BWR1C, HLDA2, IPL, TSSC3	pleckstrin homology-like domain, family A, member 2	C00001179
11145	PLA2G16, AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3	phospholipase A2, group XVI (EC:3.1.1.4 3.1.1.32)	C00001179
5340	PLG	plasminogen (EC:3.4.21.7)	C00001179
5347	PLK1, PLK, STPK13	polo-like kinase 1 (EC:2.7.11.21)	C00001179
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00001179
5376	PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110	peripheral myelin protein 22	C00001179
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00001179
5445	PON2	paraoxonase 2 (EC:3.1.1.2 3.1.1.81)	C00001179
5460	POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4	POU class 5 homeobox 1	C00001179
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001179
5588	PRKCQ, PRKCT, nPKC-theta	protein kinase C, theta (EC:2.7.11.13)	C00001179
38175			C00001179
5702	PSMC3, TBP1	proteasome (prosome, macropain) 26S subunit, ATPase, 3	C00001179
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001179
5865	RAB3B	RAB3B, member RAS oncogene family	C00001179
5870	RAB6A, RAB6	RAB6A, member RAS oncogene family	C00001179
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00001179
5889	RAD51C, BROVCA3, FANCO, R51H3, RAD51L2	RAD51 paralog C	C00001179
25788	RAD54B, RDH54	RAD54 homolog B (S. cerevisiae)	C00001179
1827	RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1	regulator of calcineurin 1	C00001179
860	RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA	runt-related transcription factor 2	C00001179
795	S100G, CABP, CABP1, CABP9K, CALB3	S100 calcium binding protein G	C00001179
5055	SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	C00001179
83667	SESN2, HI95, SES2, SEST2	sestrin 2	C00001179
6439	SFTPB, PSP-B, SFTB3, SFTP3, SMDP1, SP-B	surfactant protein B	C00001179
6472	SHMT2, GLYA, SHMT	serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1)	C00001179
6476	SI	sucrase-isomaltase (alpha-glucosidase) (EC:3.2.1.10 3.2.1.48)	C00001179
4891	SLC11A2, DCT1, DMT1, NRAMP2	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	C00001179
10864	SLC22A7, NLT, OAT2	solute carrier family 22 (organic anion transporter), member 7	C00001179
9963	SLC23A1, SLC23A2, SVCT1, YSPL3	solute carrier family 23 (ascorbic acid transporter), member 1	C00001179
9962	SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2	solute carrier family 23 (ascorbic acid transporter), member 2	C00001179
79677	SMC6, SMC-6, SMC6L1, hSMC6	structural maintenance of chromosomes 6	C00001179
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001179
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00001179
6657	SOX2, ANOP3, MCOPS3	SRY (sex determining region Y)-box 2	C00001179
6667	SP1	Sp1 transcription factor	C00001179
6670	SP3, SPR2	Sp3 transcription factor	C00001179
6671	SP4, HF1B, SPR-1	Sp4 transcription factor	C00001179
6678	SPARC, ON	secreted protein, acidic, cysteine-rich (osteonectin)	C00001179
6696	SPP1, BNSP, BSPI, ETA-1, OPN	secreted phosphoprotein 1	C00001179
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00001179
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00001179
9262	STK17B, DRAK2	serine/threonine kinase 17b (EC:2.7.11.1)	C00001179
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00001179
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00001179
20888			C00001179
6822	SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14)	C00001179
6876	TAGLN, SM22, SMCC, TAGLN1, WS3-10	transgelin	C00001179
6897	TARS, ThrRS	threonyl-tRNA synthetase (EC:6.1.1.3)	C00001179
6901	TAZ, BTHS, CMD3A, EFE, EFE2, G4.5, LVNCX, Taz1	tafazzin	C00001179
7018	TF, PRO1557, PRO2086, TFQTL1	transferrin	C00001179
7032	TFF2, SML1, SP	trefoil factor 2	C00001179
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00001179
7076	TIMP1, CLGI, EPA, EPO, HCI, TIMP	TIMP metallopeptidase inhibitor 1	C00001179
4071	TM4SF1, H-L6, L6, M3S1, TAAL6	transmembrane 4 L six family member 1	C00001179
164656	TMPRSS6, IRIDA	transmembrane protease, serine 6	C00001179
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001179
4982	TNFRSF11B, OCIF, OPG, TR1	tumor necrosis factor receptor superfamily, member 11b	C00001179
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00001179
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00001179
11257	TP53TG1, LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1	TP53 target 1 (non-protein coding)	C00001179
57761	TRIB3, C20orf97, NIPK, SINK, SKIP3, TRB3	tribbles pseudokinase 3	C00001179
9322	TRIP10, CIP4, HSTP, STOT, STP	thyroid hormone receptor interactor 10	C00001179
7224	TRPC5, TRP5	transient receptor potential cation channel, subfamily C, member 5	C00001179
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00001179
7319	UBE2A, HHR6A, MRXS30, MRXSN, RAD6A, UBC2	ubiquitin-conjugating enzyme E2A (EC:6.3.2.19)	C00001179
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00001179
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00001179
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00001179
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00001179
7428	VHL, HRCA1, RCA1, VHL1, pVHL	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	C00001179
55350	VNN3, HSA238982	vanin 3	C00001179
7443	VRK1, PCH1, PCH1A	vaccinia related kinase 1 (EC:2.7.11.1)	C00001179
7453	WARS, GAMMA-2, IFI53, IFP53	tryptophanyl-tRNA synthetase (EC:6.1.1.2)	C00001179
10352	WARS2, TrpRS	tryptophanyl tRNA synthetase 2, mitochondrial (EC:6.1.1.2)	C00001179
25937	WWTR1, TAZ	WW domain containing transcription regulator 1	C00001179
7512	XPNPEP2, APP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (EC:3.4.11.9)	C00001179
7515	XRCC1, RCC	X-ray repair complementing defective repair in Chinese hamster cells 1	C00001179
7718	ZNF165, CT53, LD65, ZSCAN7	zinc finger protein 165	C00001179

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions