KCF-S cluster No. 8847 (1 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|
Cumulative family count
| class name | count |
|---|
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00018711
|
Cerulenin
/ Helicocerin / (+)-Cerulenin |
CHEMBL45627
CHEMBL2000322 |
D002569
|
8 / 19 / 12 | 6 / 2 |
|
Human Protein / Gene in interactions
8 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16637 | Survival motor neuron protein | Unclassified protein | C00018711 | 4 / 1 |
| P04062 | Glucosylceramidase | Enzyme | C00018711 | 6 / 4 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00018711 | 3 / 1 |
| P49327 | Fatty acid synthase | Transferase | C00018711 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00018711 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00018711 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00018711 | 4 / 3 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00018711 | 0 / 0 |
6 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 83939 | EIF2A, EIF-2A, MST089, MSTP004, MSTP089 | eukaryotic translation initiation factor 2A, 65kDa |
C00018711
|
| 2081 | ERN1, IRE1, IRE1P, IRE1a, hIRE1p | endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1) |
C00018711
|
| 2194 | FASN, FAS, OA-519, SDR27X1 | fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39) |
C00018711
|
| 3172 | HNF4A, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14 | hepatocyte nuclear factor 4, alpha |
C00018711
|
| 6462 | SHBG, ABP, SBP, TEBG | sex hormone-binding globulin |
C00018711
|
| 7494 | XBP1, TREB5, XBP-1, XBP2 | X-box binding protein 1 |
C00018711
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (19)
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (12)
| KEGG | name | UniProt |
|---|---|---|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|