| class name | count |
|---|---|
| eudicotyledons | 18 |
| rosids | 8 |
| Magnoliophyta | 7 |
| Liliopsida | 1 |
| Spermatophyta | 1 |
| class name | count |
|---|---|
| Menispermaceae | 16 |
| Rutaceae | 8 |
| Annonaceae | 3 |
| Lauraceae | 3 |
| Aristolochiaceae | 1 |
| Amaryllidaceae | 1 |
| Ranunculaceae | 1 |
| Nelumbonaceae | 1 |
| Gnetaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00025347
|
Tembetarine
/ (+)-Tembetarine |
C003383
|
|
|||
|
C00025934
|
Lotusine
/ (-)-Lotusine / D-(-)-Lotusine |
|
||||
|
C00025937
|
Magnocurarine
/ (-)-Magnocurarine / (R)-Magnocurarine |
CHEMBL1187634
CHEMBL1963333 |
C048506
|
|
||
|
C00025982
|
Oblongine
/ (+)-Oblongine |
CHEMBL457373
|
C081049
|
|
||
|
C00026024
|
Reticuline N-oxide
|
CHEMBL1402907
|
7 / 7 / 4 |
|
||
|
C00027424
|
N-Methylarmepavine
|
CHEMBL1187350
|
|
|||
|
C00027554
|
Isotembetarine
/ (+)-Isotembetarine / (R)-(+)-Isotembetarine |
|
||||
|
C00027601
|
(-)-8-O-Methyloblongine
|
|
||||
|
C00028490
|
Lotusine
|
|
||||
|
C00049555
|
(-)-N-Methylhigenamine N-oxide
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00026024 | 1 / 1 |
| Q9HBX9 | Relaxin receptor 1 | Relaxin receptor | C00026024 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00026024 | 2 / 0 |
| Q9Y256 | CAAX prenyl protease 2 | U48 | C00026024 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00026024 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00026024 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00026024 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|