KCF-S cluster No. 9 (265 metabolites)

Corresponding Phytochemical cluster No. 51

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (265)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	172
eudicotyledons	83
rosids	73
Liliopsida	3

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Cumulative family count (Top 20)

class name	count
Araliaceae	71
Fabaceae	37
Amaranthaceae	29
Asteraceae	24
Rubiaceae	21
Aquifoliaceae	20
Sapindaceae	18
Phytolaccaceae	12
Ranunculaceae	11
Balsaminaceae	9
Basellaceae	8
Apiaceae	8
Zygophyllaceae	6
Sapotaceae	5
Caryophyllaceae	5
Lardizabalaceae	5
Hippocastanaceae	5
Olacaceae	5
Campanulaceae	4
Berberidaceae	4

KEGG BRITE br08003

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Categories (3)

br08003 Category	# of metabolite
Others	9
Oleananes	10
Dammarenes	3

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metabolites link (24)

br08003 Category	KEGG ID	KNApSAcK ID
Others	C08923	C00003499
Others	C08930	C00003504
Others	C08932	C00003506
Others	C08940	C00003514
Others	C08941	C00003515
Oleananes	C08943	C00003517
Oleananes	C02284	C00003522
Others	C08952	C00003526
Oleananes	C08954	C00003528
Oleananes	C08955	C00003529
Others	C08958	C00003532
Others	C08959	C00003533
Oleananes	C08962	C00003536
Oleananes	C08963	C00003537
Others	C08966	C00003540
Dammarenes	C08983	C00003553
Oleananes	C08984	C00003554
Oleananes	C08990	C00003560
Oleananes	C08943	C00024135
Oleananes	C17543	C00029947
Dammarenes	C13837	C00030105
Oleananes	C17540	C00032814
Oleananes	C17540	C00038486
Dammarenes	C12081	C00040337

Metabolite list (265)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003499	Arvensoside A
C00003504	Azukisaponin III
C00003506	Bayogenin 3-O-cellobioside
C00003514	Desglucomusennin
C00003515	Dianoside A
C00003517	Flaccidin B
C00003522	Glycyrrhizin	CHEMBL441687 CHEMBL553386 CHEMBL1974589 CHEMBL2079509 CHEMBL2220802	D019695	100 / 40 / 34	3 / 12
C00003526	Gypsogenin 3-O-rhamnosylglucuronide
C00003528	Sapindoside A / alpha-Hederin / (+)-Sapindoside A / Kalopanaxsaponin A / (+)-Kalopanaxsaponin A / Hederagenin 3-O-alpha-L-rhamnopyranosyl(1->2)-alpha-L-arabinopyranoside	CHEMBL447565 CHEMBL503131 CHEMBL525085 CHEMBL1437395 CHEMBL1980760	C010177	4 / 18 / 47
C00003529	beta-Hederin	CHEMBL506816 CHEMBL502407
C00003532	Lemmatoxin
C00003533	Medicagenic acid 3-O-triglucoside
C00003536	Olaxoside
C00003537	Oleanoglycotoxin-A
C00003540	Pfaffoside A
C00003553	Soyasaponin I	CHEMBL511016	C056684		2 / 1
C00003554	Spinasaponin A	CHEMBL503302
C00003560	Yiamoloside B
C00019003	Soyasaponin V / Soyasaponin Ba	CHEMBL505590
C00019147	GM-2 / Hispidacin / Azukisaponin V	CHEMBL511016	C072358
C00024126	Abrussaponin I
C00024127	Abrussaponin II
C00024135	Flaccidin B	CHEMBL540220 CHEMBL1997061
C00029616	Acanthopanaxoside E / (-)-Acanthopanaxoside E
C00029634	Achyranthoside A
C00029635	Achyranthoside B / Betavulgaroside I
C00029636	Achyranthoside C
C00029637	Achyranthoside D
C00029638	Spinacoside C / Achyranthoside E / (+)-Spinacoside C
C00029639	Achyranthoside F
C00029640	Achyranthoside G
C00029641	Achyranthoside H
C00029719	Arganine P
C00029720	Arganine Q
C00029759	Asterbatanoside D
C00029813	Bernardioside B2
C00029946	Momordin IIb / Silphioside G / Chikusetsusaponin IVa / Oleanolic acid 3-O-[beta-D-glucuronopyranosyl]-28-O-bet.-D-glucopyranoside	CHEMBL1095348 CHEMBL1725204	C098580	8 / 6 / 5
C00029947	Ginsenoside Ro / Polysciasaponin P3 / Chikusetsusaponin 5 / Chikusetsusaponin V	CHEMBL488317	C064378
C00029968	Cirensenoside P / 3-O-beta-D-glucopyranosyl, 28-O-beta-D-glucopyranosyl(1->6)-beta-D-glucopyranosyl betulinate
C00030105	Dehydrosoyasaponin I		C071764
C00030382	Giganteoside D / (+)-Giganteoside D	CHEMBL506816 CHEMBL502407
C00030469	Hemsgiganoside B
C00030509	Ilexoside XLVIII	CHEMBL454262		1 / 0 / 0
C00030869	Oblonganoside B / (-)-Oblonganoside B
C00030870	Oblonganoside C / (+)-Oblonganoside C
C00030871	Oblonganoside D / (-)-Oblonganoside D
C00030873	Oblonganoside F / (+)-Oblonganoside F
C00030977	Pharbitoside A
C00030978	Pharbitoside B / (-)-Pharbitoside B
C00031057	Platycoside F / (-)-Platycoside F
C00031062	Platycoside K
C00031063	Platycoside L
C00031064	Platycoside M-2
C00031213	Rotundioside K / (-)-Rotundioside K
C00031381	Silphioside G / (+)-Silphioside G	CHEMBL1095348 CHEMBL1725204	C098580	8 / 6 / 5
C00031560	Acantrifoside C
C00031613	Atriplicosaponin A	CHEMBL537960
C00031614	Atriplicosaponin B / (+)-Atriplicosaponin B
C00031687	Collinsonidin / Hederagenin 3-O-beta-D-glucopyranosyl(1->3)-alpha-L-arabinopyranoside
C00031735	Dianoside G		C423334
C00031755	Durupcoside C / (+)-Durupcoside C
C00032089	Raddeanoside R13 / Oleanolic acid 3-O-alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->4)-alpha-L-arabinopyranoside	CHEMBL444941 CHEMBL489103
C00032111	Pastuchoside B
C00032141	Sinocrassuloside I / (+)-Sinocrassuloside I
C00032248	Subproside II
C00032556	Zygophyloside P / (+)-Zygophyloside P
C00032647	3-Epibetulinic acid 28-O-alpha-L-rhamnopyranosyl-(1-.4)-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester / (-)-3-Epibetulinic acid 28-O-alpha-L-rhamnopyranosyl-(1-.4)-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester
C00032688	Acankoreoside A / Oplopanaxoside A	CHEMBL1269324
C00032690	Acankoreoside B / (-)-Acankoreoside B
C00032692	Acankoreoside D / (-)-Acankoreoside D	CHEMBL1269325
C00032694	Acantrifoside A / (-)-Acantrifoside A	CHEMBL1269327
C00032713	Araliasaponin I (Aralia elata) / (-)-Araliasaponin I (Aralia elata)
C00032714	Araliasaponin II (Aralia elata)
C00032742	Asiaticoside	CHEMBL1789965	C004446		2 / 1
C00032743	Asiaticoside B
C00032755	Basellasaponin A / (+)-Basellasaponin A
C00032756	Basellasaponin B / (+)-Basellasaponin B
C00032757	Basellasaponin C / (+)-Basellasaponin C
C00032758	Basellasaponin D / (+)-Basellasaponin D
C00032796	Calendasaponin B / (+)-Calendasaponin B
C00032800	Calenduloside G / (+)-Calenduloside G	CHEMBL503302
C00032805	Centellasaponin B / (+)-Centellasaponin B
C00032806	Centellasaponin C / (+)-Centellasaponin C
C00032807	Centellasaponin D
C00032813	Chiisanoside	CHEMBL507957		1 / 0 / 0
C00032814	Araloside A / Chikusetsusaponin IV	CHEMBL1773982	C071578
C00032816	Chikusetsusaponin V methyl ester
C00032865	Cussonoside B / Hederacaucaside B	CHEMBL1171448	C049388	2 / 0 / 3
C00032872	Cussosaponin A / (-)-Cussosaponin A
C00032875	Cussosaponin D / (-)-Cussosaponin D
C00032933	Elatoside A / Tarasaponin II
C00032947	Esculentoside G		C075948
C00032948	Esculentoside L1 / (+)-Esculentoside L1
C00032949	Esculentoside S / (+)-Esculentoside S	CHEMBL254344		1 / 1 / 0
C00032962	Eupteleasaponin IX / (+)-Eupteleasaponin IX
C00032967	Eupteleasaponin X / (+)-Eupteleasaponin X
C00032970	Fargoside A / (+)-Fargoside A
C00032971	Fargoside B / (+)-Fargoside B
C00032972	Fargoside C / (+)-Fargoside C
C00032973	Fargoside D / (+)-Fargoside D
C00032974	Fargoside E / (+)-Fargoside E
C00033090	Kaikasaponin III		C111015
C00033110	Latifoloside L / Randiasaponin III / (-)-Latifoloside L / (-)-Randiasaponin III	CHEMBL503930 CHEMBL1712471		4 / 2 / 0
C00033137	Madecassoside / Asiaticoside A	CHEMBL447019	C093443		2 / 0
C00033200	Momordin IIc / (+)-Momordin IIc
C00033238	Myrioside C / (-)-Myrioside C
C00033239	Myrioside D / (-)-Myrioside D
C00033299	Phytolaccoside E	CHEMBL237885 CHEMBL404391	C076297	2 / 1 / 3
C00033301	Pictoside A / (-)-Pictoside A
C00033311	Pisumsaponin II / (-)-Pisumsaponin II
C00033499	Wujiapioside B	CHEMBL1986122
C00033566	3-O-alpha-L-arabinopyranosylserjanic acid 28-O-beta-D-glucopyranosyl ester
C00033709	Cauloside C / (+)-Cauloside C	CHEMBL537960	C018245
C00034064	Mukurozisaponin E1	CHEMBL1078507
C00034065	Mukurozisaponin G	CHEMBL1078505 CHEMBL1482513		5 / 1 / 0
C00034165	Polygalasaponin XLVII / (+)-Polygalasaponin XLVII
C00034180	Pteleopsoside / (+)-Pteleopsoside
C00034186	Quinoasaponin 1
C00034187	Quinoasaponin 2
C00034188	Quinoasaponin 3 / (+)-Quinoasaponin 3
C00034189	Quinoasaponin 4
C00034190	Quinoasaponin 5
C00034192	Quinoasaponin 9	CHEMBL454262		1 / 0 / 0
C00034210	Sapindoside B / (+)-Sapindoside B		C061619
C00034211	Sapinmusaponin K / (+)-Sapinmusaponin K
C00034212	Sapinmusaponin L / (+)-Sapinmusaponin L	CHEMBL1078507
C00034213	Sapinmusaponin M / (-)-Sapinmusaponin M
C00034214	Sapinmusaponin N / (+)-Sapinmusaponin N	CHEMBL1078506
C00034217	Saponin PE	CHEMBL540220 CHEMBL1997061
C00034425	3-O-[beta-D-xylopyranosyl-(1->2)-alpha-L-arabinopyranosyl-(1->6)-2-acetamido-2-deoxy-beta-D-glucopyranosyl] acacic acid lactone	CHEMBL509569 CHEMBL1765594
C00034426	Acacioside A / 3-O-[beta-D-xylopyranosyl-(1->2)-alpha-L-arabinopyranosyl-(1->6)-2-acetamido-2-deoxy-beta-D-glucopyranosyl] echinocystic acid
C00034782	Aesculioside Ia	CHEMBL1095023
C00034783	Aesculioside Ib / (-)-Aesculioside Ib	CHEMBL1095021
C00034784	Aesculioside Ic / (-)-Aesculioside Ic	CHEMBL1095024
C00034785	Aesculioside Id / (-)-Aesculioside Id	CHEMBL1095020
C00034786	Aesculioside Ie / (-)-Aesculioside Ie	CHEMBL1095022
C00034796	Arborenin
C00034833	Desacylescin III
C00035063	Caryocaroside II-22
C00035066	Caryocaroside II-7 / (+)-Caryocaroside II-7	CHEMBL451048
C00035067	Caryocaroside III-22
C00035738	Salsoloside C	CHEMBL2138579		1 / 0 / 0
C00035739	Salsoloside D
C00035936	3-O-beta-D-glucopyranosyl-(1->2)-beta-D-quinovopyranosyl quinovic acid
C00035988	Acankoreoside E
C00036558	Rubelloside A / 3-O-[beta-D-glucopyranosyl-(1->4)-alpha-L-rhamnopyranosyl]-quinovoic acid
C00036676	Acanjaposide A / (+)-Acanjaposide A
C00036677	Acanjaposide B / (+)-Acanjaposide B
C00036678	Acanjaposide C / (+)-Acanjaposide C
C00036679	Acanjaposide E / (+)-Acanjaposide E
C00036835	Bourneioside B / (+)-Bourneioside B
C00036896	Silphioside A / Chikusetsusaponin IVa methyl ester	CHEMBL1773984
C00036918	Clemontanoside C		C082271
C00036929	Congmuyenoside A
C00037296	Ilexoside XXXVII	CHEMBL448619		1 / 0 / 0
C00037300	Inermiside I / (-)-Inermiside I
C00037578	Oleanolic acid 3,28-beta-diglucopyranoside / (+)-Oleanolic acid 3,28-beta-diglucopyranoside	CHEMBL2004568
C00037718	Randiasaponin I / (+)-Randiasaponin I
C00037719	Randiasaponin II / (+)-Randiasaponin II
C00037720	Latifoloside A / Randiasaponin IV / (-)-Latifoloside A / (-)-Randiasaponin IV	CHEMBL505407		1 / 0 / 0
C00037721	Latifoloside B / Randiasaponin V / (-)-Latifoloside B / (-)-Randiasaponin V
C00037722	Randiasaponin VI / (+)-Randiasaponin VI
C00037723	Randiasaponin VII / (+)-Randiasaponin VII
C00037734	Rivaloside A / (+)-Rivaloside A
C00037735	Rivaloside B / (-)-Rivaloside B
C00037736	Rivaloside C / (-)-Rivaloside C
C00037737	Rivaloside D / (-)-Rivaloside D
C00037738	Ilexoside L / Rivaloside E / (+)-Ilexoside L / (+)-Rivaloside E
C00037739	Robinioside E
C00037834	Sophoraflavoside II		C079026
C00037840	Staunoside A / 3-O-beta-D-Glucopyranosyl hederagenin 28-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester
C00037849	Stipuleanoside R1
C00038382	Ageratoside B1 / (+)-Ageratoside B1
C00038384	Ageratoside C1 / (-)-Ageratoside C1
C00038428	Amaranthus-saponin I
C00038429	Amaranthus-saponin II
C00038486	Araloside J	CHEMBL1773982
C00038590	Betavulgaroside III
C00038591	Betavulgaroside V / (+)-Betavulgaroside V
C00038830	Copteroside D
C00038833	Copteroside G
C00038834	Copteroside H
C00038906	Cynarasaponin H	CHEMBL1288834
C00038907	Cynarasaponin J
C00039168	Esculentoside H	CHEMBL401863	C062558	1 / 1 / 0
C00039169	Esculentoside L	CHEMBL403995	C065156	1 / 1 / 0
C00039170	Esculentoside M	CHEMBL412721	C072886	1 / 1 / 0
C00039403	Ilexoside LI
C00039404	Udosaponin F / Ilexoside XLIX
C00039405	Ilexoside XLVI
C00039406	Ilexoside XLVII
C00039407	Ilexoside XXXI
C00040091	Pseudo-ginsenoside RT1	CHEMBL1288834
C00040238	Scaberoside B1 / (+)-Scaberoside B1
C00040239	Scaberoside B2
C00040240	Scaberoside B3
C00040241	Scaberoside B4
C00040337	Soyasaponin II		C106126		2 / 0
C00040338	Spartitrioside / (-)-Spartitrioside
C00040443	Talinumoside I / (+)-Talinumoside I
C00040445	Tarasaponin VI		C071587
C00040521	Tragopogonoside A
C00040522	Tragopogonoside C
C00040523	Tragopogonoside D
C00040551	Trichoside A
C00040724	Zanhasaponin A / (-)-Zanhasaponin A	CHEMBL450111
C00041033	Latifoloside D	CHEMBL505407		1 / 0 / 0
C00041306	Acanthopanaxoside C / (-)-Acanthopanaxoside C
C00041408	Calendulaglycoside B	CHEMBL500221
C00041409	Calendulaglycoside C	CHEMBL504681 CHEMBL1288832
C00041410	Taibaienoside IV / Calenduloside F 6'-O-n-butyl ester / (+)-Calenduloside F 6'-O-n-butyl ester	CHEMBL502145
C00041774	Polygalasaponin E / (-)-Polygalasaponin E	CHEMBL503227
C00041778	Polygalasaponin II	CHEMBL1689554
C00041863	Sessiloside	CHEMBL447549		1 / 0 / 0
C00043009	Snatzkein C / (-)-Snatzkein C
C00043010	Snatzkein D / (-)-Snatzkein D
C00043764	Nephelioside I	CHEMBL488528
C00043765	Nephelioside II / (+)-Nephelioside II	CHEMBL510267
C00043766	Nephelioside III	CHEMBL508768
C00043767	Nephelioside IV / (+)-Nephelioside IV	CHEMBL448391
C00043768	Nephelioside V / (+)-Nephelioside V	CHEMBL477836
C00043769	nephelioside VI / (+)-nephelioside VI	CHEMBL475194
C00043994	Udosaponin B	CHEMBL488317
C00044105	Baptisiasaponin I
C00044269	Nudicaucin A / (+)-Nudicaucin A
C00044270	Nudicaucin B / (+)-Nudicaucin B	CHEMBL507155
C00044304	Scabrioside A / (-)-Scabrioside A
C00044390	Zygophyloside J
C00044391	Zygophyloside K
C00045110	Tomentoside A / (-)-Tomentoside A
C00045111	Tomentoside B / (-)-Tomentoside B
C00045624	Albiziasaponin A / (-)-Albiziasaponin A	CHEMBL491529
C00045625	Albiziasaponin B
C00045683	Bidentatoside I	CHEMBL525990
C00045801	Conyzasaponin G
C00046550	11-Deoxyisochiisanoside
C00046567	1-Deoxychiisanoside
C00046575	24-Hydroxychiisanoside / (-)-24-Hydroxychiisanoside
C00046764	Hederacoside A
C00046777	Inermoside / (-)-Inermoside
C00046808	Madlongiside B / (+)-Madlongiside B	CHEMBL504216
C00046810	Madlongiside D / (-)-Madlongiside D	CHEMBL508213
C00046824	Mimusopside A
C00046895	Sandrosaponin X / (+)-Sandrosaponin X
C00047362	23-Hydroxyursolic acid 28-O-alpha-L-rhamnopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester	CHEMBL1684591
C00048422	Impatienoside A / (-)-Impatienoside A
C00048423	Impatienoside B / (+)-Impatienoside B
C00048524	Rarasaponin I	CHEMBL1078504
C00048530	Sandosaponin A
C00048543	Soyasaponin Bg
C00048544	Soyasaponin I methyl ester
C00048545	Soyasaponin IV
C00049235	Nipponoside A / (-)-Nipponoside A
C00049238	Nipponoside D / (-)-Nipponoside D
C00049239	Nipponoside E / (-)-Nipponoside E
C00049271	Polyscioside A / (+)-Polyscioside A
C00049272	Polyscioside B / (+)-Polyscioside B
C00049273	Polyscioside C / (+)-Polyscioside C	CHEMBL500221
C00049559	Ilekudinoside B / (-)-Ilekudinoside B	CHEMBL488832		1 / 0 / 0
C00049560	Ilekudinoside C / (+)-Ilekudinoside C	CHEMBL501236		1 / 0 / 0
C00049565	Cynarasaponin C
C00049848	Zygophyloside M / (+)-Zygophyloside M
C00049894	Pulsatilloside C	CHEMBL1986122
C00050082	Eclalbasaponin I / (+)-Eclalbasaponin I
C00050084	Eclalbasaponin III

Human Protein / Gene in interactions

116 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P35610	Sterol O-acyltransferase 1	Enzyme	C00030509 C00033110 C00034192 C00037296 C00037720 C00041033 C00049559 C00049560	0 / 0
P08183	Multidrug resistance protein 1	drug	C00032949 C00033299 C00039168 C00039169 C00039170	1 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00003522 C00029946 C00031381 C00035738	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00029946 C00031381 C00033110	2 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00003522 C00003528 C00034065	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00029946 C00031381 C00033110	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00003522 C00032865 C00033299	0 / 3
P16233	Pancreatic triacylglycerol lipase	Hydrolase	C00032813 C00041863	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00029946 C00031381	1 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00029946 C00031381	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00029946 C00031381	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00003522 C00034065	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00003522 C00032865	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00029946 C00031381	2 / 3
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00003522 C00034065	0 / 0
O75496	Geminin	Unclassified protein	C00029946 C00031381	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00003522	1 / 1
P27361	Mitogen-activated protein kinase 3	Erk	C00003522	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00003522	2 / 2
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003528	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00003528	11 / 10
P00918	Carbonic anhydrase 2	Lyase	C00003522	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00003522	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00003522	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00003522	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00003522	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00003522	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00003522	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00003522	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00003522	0 / 0
P29466	Caspase-1	C14	C00003522	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00003522	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00003522	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00003522	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003522	0 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00003522	1 / 8
P06746	DNA polymerase beta	Enzyme	C00034065	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00003522	2 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00003522	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00003522	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00003522	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00003522	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00003522	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00003522	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00003522	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00003522	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00003522	1 / 0
P28845	Corticosteroid 11-beta-dehydrogenase isozyme 1	Enzyme	C00003522	1 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00003522	0 / 0
P08246	Neutrophil elastase	S1A	C00003522	2 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00003522	2 / 2
P46721	Solute carrier organic anion transporter family member 1A2	Unclassified protein	C00003522	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00003522	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00003522	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00003522	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00003522	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00003522	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00003522	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00003522	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00003522	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00003522	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00003522	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00003522	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00003522	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00003522	0 / 0
P08311	Cathepsin G	S1A	C00003522	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00003522	1 / 0
P03956	Interstitial collagenase	M10A	C00003522	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00003522	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00003522	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00003522	1 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00003522	1 / 0
P04150	Glucocorticoid receptor	NR3C1	C00003522	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00003522	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00003522	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00003522	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00003522	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00003522	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00003522	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00003522	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00003522	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00003522	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00003522	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00003522	1 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00003528	7 / 37
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00003522	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003522	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00003522	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003522	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00003522	0 / 0
P03372	Estrogen receptor	NR3A1	C00003522	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00003522	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00003522	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00003522	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00003522	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00003522	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00003522	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00003522	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00003522	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00003522	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003522	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003522	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00003522	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00033110	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00034065	1 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00003522	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00003522	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00003522	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00003522	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00003522	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00003522	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00003522	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003522	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00003522	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003522	1 / 0
P09429	High mobility group protein B1	Unclassified protein	C00003522	0 / 0

6 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5972	REN, HNFJ2	renin (EC:3.4.23.15)	C00003522 C00003553 C00040337
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00003522 C00032742 C00033137
1557	CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19	cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00032742 C00033137
6484	ST3GAL4, CGS23, NANTA3, SAT3, SIAT4, SIAT4C, ST3GalIV, STZ	ST3 beta-galactoside alpha-2,3-sialyltransferase 4 (EC:2.4.99.4)	C00003553
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00040337
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00003522

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions