KCF-S cluster No. 90 (51 metabolites)

Corresponding Phytochemical cluster No. 13

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (51)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Magnoliophyta	40
rosids	29
Euphyllophyta	16
asterids	14
Liliopsida	13
eudicotyledons	2

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Cumulative family count (Top 20)

class name	count
Pteridaceae	15
Myristicaceae	15
Salicaceae	15
Annonaceae	13
Ericaceae	8
Myricaceae	8
Lauraceae	7
Ruscaceae	6
Piperaceae	5
Asparagaceae	4
Meliaceae	2
Asteraceae	2
Phrymaceae	2
Adoxaceae	2
Fabaceae	2
Myrtaceae	2
Zingiberaceae	1
Ranunculaceae	1
Polygonaceae	1
Orchidaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Dihydrochalcones	2

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Dihydrochalcones	C09471	C00000940
Dihydrochalcones	C09644	C00007929

Metabolite list (51)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000940	Asebogenin	CHEMBL253257
C00007922	2',4'-Dihydroxydihydrochalcone
C00007923	Loureirin C	CHEMBL253778
C00007924	2,4'-Dihydroxy-4-methoxydihydrochalcone	CHEMBL1081513
C00007925	Loureirin A	CHEMBL253779
C00007927	4'-O-Methyldavidigenin	CHEMBL490352
C00007928	2',4',6'-Trihydroxydihydrochalcone / 3-Phenyl-1-(2,4,6-trihydroxyphenyl)-1-propanone	CHEMBL503375		8 / 5 / 4
C00007929	2',6'-Dihydroxy-4'-methoxydihydrochalcone	CHEMBL486009
C00007930	Uvangoletin
C00007931	Dihydroflavokawin B	CHEMBL492166
C00007932	Loureirin D	CHEMBL400281
C00007933	Loureirin B
C00007934	4,2',4'-Trihydroxy-3-methoxydihydrochalcone
C00007935	Dihydrocalythropsin		C085138
C00007937	2',4',6'-Trihydroxy-4-methoxydihydrochalcone
C00007938	4,2',4'-Trihydroxy-6'-methoxydihydrochalcone
C00007939	Calomelanone
C00007940	2',4'-Dihydroxy-4,6'-dimethoxydihydrochalcone	CHEMBL255287
C00007941	Dihydropashanone
C00007943	2',6'-Dihydroxy-3,4,4'-trimethoxydihydrochalcone
C00007944	2',4'-Dihydroxy-3,4,6'-trimethoxydihydrochalcone
C00007945	Dihydropedicin
C00007946	Dihydrokanakugiol
C00007953	2',4'-Dihydroxy-3,4-methylenedioxydihydrochalcone
C00007955	2',4'-Dihydroxy-6'-methoxy-3,4-methylenedioxydihydrochalcone	CHEMBL403150
C00007995	2'-Hydroxy-4',6'-dimethoxy-3'-methyldihydrochalcone
C00007997	Myrigalon B
C00007998	Angoletin	CHEMBL452234	C105002
C00007999	4,2',6'-Trihydroxy-4'-methoxy-3'-methyldihydrochalcone
C00008000	4,2',6'-Trihydroxy-4'-methoxy-3',5'-dimethyldihydrochalcone
C00008117	Myrigalone H / 2',4'-Dihydroxy-6'-methoxy-3'-methyldihydrochalcone
C00008118	2',6'-Dihydroxy-4'-methoxy-3'-methyldihydrochalcone
C00008125	Lusianin / 2',4'-Dihydroxy-4,3'-dimethoxydihydrochalcone
C00014591	2'-Hydroxy-4'-methoxydihydrochalcone / 2'-Hydroxy-4'-methoxy-3-phenylpropiophenone	CHEMBL1698547		6 / 3 / 3
C00014592	2'-Methoxy-4'-hydroxydihydrochalcone
C00014593	2-Methoxy-4-hydroxydihydrochalcone
C00014594	3'-Methyl-2',4',6'-trihydroxydihydrochalcone	CHEMBL496931
C00014595	4-Hydroxy-2',4'-dimethoxydihydrochalcone
C00014597	4'-Hydroxy-2,6-dimethoxydihydrochalcone
C00014598	2',3'-Dihydroxy-4',6'-dimethoxydihydrochalcone
C00014599	2'-Hydroxy-3',4',6'-trimethoxydihydrochalcone
C00014600	Dihydroflavokawain C / 4,2'-Dihydroxy-4',6'-dimethoxydihydrochalcone	CHEMBL481649
C00014601	Flavokawin A / Flavokavain A	CHEMBL523190
C00014603	2,4'-Dihydroxy-4,6-dimethoxydihydrochalcone
C00014604	4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone	CHEMBL400283
C00014605	2-Hydroxy-3,4,6-trimethoxydihydrochalcone
C00014606	2-Hydroxy-4,5,6-trimethoxydihydrochalcone
C00014607	3',5'-Dihydroxy-2',4',6'-trimethoxydihydrochalcone
C00030253	Flavokavain C	CHEMBL481649
C00033901	Helichrysone B
C00042139	4'-Hydroxy-2',6'-dimethoxydihydrochalcone

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UNA4	DNA polymerase iota	Enzyme	C00007928 C00014591	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00007928 C00014591	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00007928 C00014591	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00007928	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00014591	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00014591	2 / 3
Q96LD8	Sentrin-specific protease 8	Enzyme	C00007928	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00007928	4 / 3
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00014591	1 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00007928	0 / 0
Q9HCT0	Fibroblast growth factor 22	Unclassified protein	C00007928	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions