| class name | count |
|---|---|
| rosids | 8 |
| Magnoliophyta | 2 |
| asterids | 1 |
| eudicotyledons | 1 |
| class name | count |
|---|---|
| Ganodermataceae | 49 |
| Euphorbiaceae | 6 |
| Coriolaceae | 6 |
| Meliaceae | 2 |
| Annonaceae | 2 |
| Polyporaceae | 1 |
| Gentianaceae | 1 |
| Coulaceae | 1 |
| Hypocreaceae | 1 |
| Xylariaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00023777
|
Lanosta-7,9(11),24-triene-3beta,21-diol
|
|
||||
|
C00023782
|
3beta-Hydroxylanosta-7,9(11),24-trien-21-oic acid
|
CHEMBL226995
CHEMBL2203608 |
|
|||
|
C00023847
|
Ganoderic acid S
/ (22S,24E)-22-Acetoxy-3alpha-hydroxy-5alpha-lanosta-7,9(11),24-trien-26-oic acid |
CHEMBL1097154
|
|
|||
|
C00023853
|
Ganoderic acid Y
/ 3beta-Hydroxy-5alpha-lanosta-7,9(11),24-trien-26-oic acid |
CHEMBL1915760
|
2 / 1 / 0 |
|
||
|
C00023857
|
Ganoderiol A
/ (+)-Ganoderiol A / 5alpha-Lanosta-7,9(11)-diene-3beta,24,25,26-tetraol |
|
||||
|
C00023858
|
Ganoderiol B
/ 15alpha,26,27-Trihydroxy-5alpha-lanosta-7,9(11),24-trien-3-one |
|
||||
|
C00023859
|
Ganoderiol C
|
|
||||
|
C00023860
|
Ganoderiol D
|
|
||||
|
C00023861
|
Ganoderiol E
|
|
||||
|
C00023862
|
Ganoderiol F
|
CHEMBL1915761
|
5 / 1 / 0 |
|
||
|
C00023863
|
Ganoderiol G
|
|
||||
|
C00023864
|
(+)-Ganoderiol H
|
|
||||
|
C00023865
|
Ganoderiol I
|
|
||||
|
C00023866
|
(+)-Ganodermanondiol
/ 24(S),25-Dihydroxy-5alpha-lanosta-7,9(11)-dien-3-one |
CHEMBL1098479
|
2 / 1 / 0 |
|
||
|
C00023867
|
Ganodermanontriol
/ 24(S),25,26-Trihydroxy-5alpha-lanosta-7,9(11)-dien-3-one |
CHEMBL1915763
CHEMBL1921821 CHEMBL1923792 CHEMBL1923793 |
3 / 1 / 0 |
|
||
|
C00023868
|
Ganodermadiol
/ 5alpha-Lanosta-7,9(11),24-triene-3beta,26-one |
CHEMBL240972
|
C050246
|
3 / 4 / 4 |
|
|
|
C00023869
|
Ganodermatriol
|
C050247
|
|
|||
|
C00023873
|
(+)-Ganolucidic acid D
/ 15alpha,23-Dihydroxy-3,11-dioxo-5alpha-lanosta-8,24E-dien-26-oic acid |
|
||||
|
C00023874
|
Ganolucidic acid E
/ 15alpha-Hydroxy-3,11-dioxo-5alpha-lanosta-8,24E-dien-26-oic acid |
CHEMBL2203593
|
|
|||
|
C00030692
|
Lucidumol A
/ (+)-Lucidumol A |
CHEMBL1917739
|
1 / 0 / 0 |
|
||
|
C00030693
|
Lucidumol B
|
CHEMBL1915762
|
2 / 1 / 0 |
|
||
|
C00032435
|
Tyromycic acid
|
CHEMBL1097154
|
|
|||
|
C00033123
|
Lucialdehyde A
|
CHEMBL515080
|
|
|||
|
C00033124
|
Lucialdehyde B
/ (+)-Lucialdehyde B |
CHEMBL463372
|
|
|||
|
C00033125
|
Lucialdehyde C
/ (+)-Lucialdehyde C |
|
||||
|
C00033850
|
Ganoderal A
/ (+)-Ganoderal A |
CHEMBL463972
|
|
|||
|
C00033851
|
Ganoderal B
/ (+)-Ganoderal B |
|
||||
|
C00033852
|
Ganoderic aldehyde A
/ (+)-Ganoderic aldehyde A |
CHEMBL490377
|
|
|||
|
C00035009
|
Carnosodione
/ 26,27-Dihydroxylanosta-7,9(11),24-triene-3,16-dione |
|
||||
|
C00036339
|
(20S)-Dammara-13(17),24-dien-3-one
/ (+)-(20S)-Dammara-13(17),24-dien-3-one |
|
||||
|
C00036592
|
5alpha-Lanosta-7,9(11),24-triene-3alpha,23-diol
/ (-)-5alpha-Lanosta-7,9(11),24-triene-3alpha,23-diol |
|
||||
|
C00037647
|
Pinicolol C
|
|
||||
|
C00038066
|
(+)-21-Hydroxylanosta-8,24-dien-3-one
|
|
||||
|
C00038212
|
21-Hydroxylanosta-7,9(11),24-trien-3-one
|
|
||||
|
C00039068
|
Dymacrin K
/ (-)-Dymacrin K |
|
||||
|
C00042525
|
Ganoderol A
|
CHEMBL463773
|
C050245
|
|
||
|
C00042526
|
Ganoderone A
|
CHEMBL457601
|
|
|||
|
C00042527
|
Ganoderone C
/ (-)-Ganoderone C |
CHEMBL516315
|
|
|||
|
C00042706
|
Lucialdehyde D
/ (+)-Lucialdehyde D |
|
||||
|
C00042861
|
Polycarpol
|
CHEMBL486808
CHEMBL1982726 |
2 / 0 / 0 |
|
||
|
C00043676
|
Lucidadiol
/ (+)-Lucidadiol |
CHEMBL1915764
|
2 / 1 / 0 |
|
||
|
C00043992
|
Tyromycic acid D
/ (-)-Tyromycic acid D |
CHEMBL479332
|
|
|||
|
C00044417
|
11-Oxo-kansenonol
/ (+)-11-Oxo-kansenonol |
CHEMBL469077
|
|
|||
|
C00044744
|
epi-Kansenone
/ (-)-epi-Kansenone |
CHEMBL469279
CHEMBL513851 |
|
|||
|
C00044845
|
Kansenol
|
|
||||
|
C00044846
|
Kansenone
|
CHEMBL469279
CHEMBL513851 |
|
|||
|
C00044847
|
Kansenonol
/ (+)-Kansenonol |
CHEMBL469076
CHEMBL1078419 |
1 / 0 / 0 |
|
||
|
C00045224
|
Antiquol C
/ (-)-Antiquol C |
CHEMBL517452
|
|
|||
|
C00045319
|
Ganoderic acid DM
|
CHEMBL1099224
|
1 / 3 / 4 |
|
||
|
C00045821
|
Daldinialanone
/ (+)-Daldinialanone |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P06276 | Cholinesterase | Hydrolase | C00023853 C00023862 C00023866 C00023867 C00023868 C00030693 C00043676 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00023853 C00023862 C00023866 C00023867 C00023868 C00030693 C00043676 | 1 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00023862 C00023867 C00030692 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00023868 C00045319 | 3 / 4 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00023862 | 0 / 0 |
| Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | C00042861 | 0 / 0 |
| P55055 | Oxysterols receptor LXR-beta | NR1H3 | C00042861 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00023862 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00044847 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #112100 | Yt blood group antigen |
P22303
|
| KEGG | name | UniProt |
|---|---|---|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|