PCIDB

Strachybotrys alternans

Species

KNApSAcK Entry

Organism name Strachybotrys alternans
Genus
Family
Kingdom

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00003647 External link 512 Campesterol
/ 24alpha-Methylcholesterol
/ (24R)24-Methylcholest-5-en-3beta-ol
CHEMBL520535
CHEMBL485421
CHEMBL1836653
C021273
No. 53 No. 11
C00003672 External link 512 Sitosterol
/ beta-sitosterl
/ (-)-beta-Sitosterol
/ Stigmast-5-en-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11
C00023770 External link 512 Sitosterol
/ Stigmasta-5,22-dien-3beta-ol
/ (24R)24-Ethylcholesta-5,22-dien-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003672 C00023770 1 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00003672 C00023770 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003672 C00023770 2 / 0
P06746 DNA polymerase beta Enzyme C00003672 C00023770 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003672 C00023770 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00003672 C00023770 3 / 2
P08183 Multidrug resistance protein 1 drug C00003672 C00023770 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003672 C00023770 0 / 1
P49841 Glycogen synthase kinase-3 beta Gsk C00003672 C00023770 0 / 0
P00734 Prothrombin S1A C00003672 C00023770 4 / 2
P14679 Tyrosinase Oxidoreductase C00003672 C00023770 4 / 2
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003672 C00023770 0 / 0
P03372 Estrogen receptor NR3A1 C00003672 C00023770 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003672 C00023770 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003672 C00023770 0 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003672 C00023770 1 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003672 C00023770 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#218030 Apparent mineralocorticoid excess; ame P80365
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (12)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)