Species

KNApSAcK Entry

Organism name Dictyuchus monosporus
Genus
Family
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Dictyuchus monosporus
Linked NCBI taxonomy ID 120407
Linked level species

Family

Family in NCBI taxonomy Saprolegniaceae
ID 4764

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Eukaryota
ID 2759

Plant class

Plant class
ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003652 External link 512 Ergosterol
/ Ergosta-5,7,22-trien-3beta-ol
CHEMBL222608
CHEMBL1232562
CHEMBL1512075
CHEMBL1741735
CHEMBL1965225
D004875
12 / 14 / 11 No. 111 No. 11
C00023744 External link 512 Lathosterol
/ Cholest-7-en-3beta-ol
CHEMBL1515367
C001521
7 / 7 / 10 0 / 3 No. 111 No. 11

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P16050 Arachidonate 15-lipoxygenase Enzyme C00003652 C00023744 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00003652 C00023744 4 / 3
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003652 C00023744 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00003652 C00023744 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003652 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003652 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003652 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003652 2 / 3
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003652 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003652 0 / 1
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00003652 5 / 1
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00023744 0 / 0
P31939 Bifunctional purine biosynthesis protein PURH Enzyme C00003652 1 / 1
O00255 Menin Unclassified protein C00023744 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00023744 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#608688 Aicar transformylase/imp cyclohydrolase deficiency P31939
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#143500 Gilbert syndrome P22309
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (18)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00966 AICA-ribosiduria P31939 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)

Diseases related to CTD interactions

3 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D008607 Intellectual Disability C00023744
C537880 Lathosterolosis C00023744
D008107 Liver Diseases C00023744