PCIDB

Candida sp.

Species

KNApSAcK Entry

Organism name Candida sp.
Genus Candida
Family Saccharomycetaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Candida
Linked NCBI taxonomy ID 5475
Linked level genus

Family

Family in NCBI taxonomy
ID

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00003672 External link 512 Sitosterol
/ beta-sitosterl
/ (-)-beta-Sitosterol
/ Stigmast-5-en-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11
C00023754 External link 512 5,6-Dehydroergosterol
/ Ergosta-7,22-dien-3beta-ol
/ 24-Methylcholesta-7,22-dien-3beta-ol
CHEMBL463973
CHEMBL560819
No. 111 No. 11
C00003652 External link 512 Ergosterol
/ Ergosta-5,7,22-trien-3beta-ol
CHEMBL222608
CHEMBL1232562
CHEMBL1512075
CHEMBL1741735
CHEMBL1965225
D004875
12 / 14 / 11 No. 111 No. 11
C00023768 External link 512 4alpha-Methylzymosterol
No. 111 No. 11
C00023776 External link 512 14-Demethyllanosterol
/ 4,4-Dimethylzymosterol
C013499
No. 111 No. 11

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003652 C00003672 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003652 C00003672 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003652 C00003672 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003652 C00003672 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003652 C00003672 0 / 1
P00734 Prothrombin S1A C00003672 4 / 2
P08183 Multidrug resistance protein 1 drug C00003672 1 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003672 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003652 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00003652 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00003672 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003652 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00003672 3 / 2
P14679 Tyrosinase Oxidoreductase C00003672 4 / 2
P06746 DNA polymerase beta Enzyme C00003672 0 / 0
P03372 Estrogen receptor NR3A1 C00003672 1 / 1
P16050 Arachidonate 15-lipoxygenase Enzyme C00003652 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003672 2 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00003672 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00003652 5 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00003652 4 / 3
P31939 Bifunctional purine biosynthesis protein PURH Enzyme C00003652 1 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003672 1 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003672 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (31)

OMIM preferred title UniProt
#608688 Aicar transformylase/imp cyclohydrolase deficiency P31939
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#218030 Apparent mineralocorticoid excess; ame P80365
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#143500 Gilbert syndrome P22309
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P00734
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188050 Thrombophilia due to thrombin defect; thph1 P00734
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (20)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00966 AICA-ribosiduria P31939 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)