Species

KNApSAcK Entry

Organism name Launaea arborescens
Genus Launaea
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Launaea arborescens
Linked NCBI taxonomy ID 43199
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00034301 External link 512 Taraxast-20-ene-3beta,30-diol
/ (+)-Taraxast-20(30)-ene-3.beta.,12.beta.-diol
No. 23 No. 51
C00003749 External link 512 Lupeol
/ Lupenol
/ (+)-Lupenol
CHEMBL289191
CHEMBL459702
C010480
3 / 0 / 0 2 / 6 No. 23 No. 51
C00003674 External link 512 Stigmasterol
/ beta-Stigmasterol
CHEMBL66943
CHEMBL186373
CHEMBL400247
CHEMBL1568947
D013265
5 / 0 / 0 1 / 0 No. 53 No. 11
C00013038 External link 512 Splendolide
/ Magnolialide
/ [3aS-(3aalpha,5abeta,6beta,9bbeta)]-3a,4,5,5a,6,7,8,9b-Octahydro-6-hydroxy-5a,9-dimethyl-3-methylenenaphtho[1,2-b]furan-2(3H)-one
No. 178 No. 38
C00020809 External link 512 Crepidiaside A
No. 212
C00032170 External link 512 Sonchuside A
/ (+)-Sonchuside A
No. 212
C00020803 External link 512 Ixerisoside D
/ (-)-Ixerisoside D
No. 259 No. 38
C00012186 External link 512 Picriside C
/ (+)-Picriside C
No. 980
C00012204 External link 512 Picriside B
/ (+)-Picriside B
/ Costunolide 15-beta-D-glucopyranoside
No. 980
C00033598 External link 512 8-Deoxy-15-(3'-hydroxy-2'-methyl-propanoyl)-lactucin-3'-sulfate
No. 5275

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11388 DNA topoisomerase 2-alpha Isomerase C00003674 C00003749 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00003749 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00003674 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003749 0 / 0
P06746 DNA polymerase beta Enzyme C00003674 0 / 0
P09884 DNA polymerase alpha catalytic subunit Transferase C00003674 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00003674 0 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00003749
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) C00003749
10599 SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family, member 1B1 C00003674

Related Diseases

Diseases related to CTD interactions

6 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006528 Carcinoma, Hepatocellular C00003749
D009202 Cardiomyopathies C00003749
D006937 Hypercholesterolemia C00003749
D009374 Neoplasms, Experimental C00003749
D012878 Skin Neoplasms C00003749
D014947 Wounds and Injuries C00003749