Dictamnus radicis Cortex
Species
KNApSAcK Entry
| Organism name | Dictamnus radicis Cortex |
|---|---|
| Genus | Dictamnus |
| Family | Rutaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Dictamnus |
|---|---|
| Linked NCBI taxonomy ID | 77005 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (7)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003719
|
Limonin
|
CHEMBL1523286
CHEMBL1886762 CHEMBL1897224 CHEMBL2004366 |
C001546
|
2 / 0 / 1 | 1 / 1 | No. 204 | No. 51 |
|
|
C00003723
|
Obacunone
|
CHEMBL404140
|
C067207
|
1 / 0 / 0 | 8 / 0 | No. 204 | No. 51 |
|
|
C00030241
|
Evodol
/ Limonin diosphenol |
CHEMBL521514
|
No. 204 | No. 51 |
|
|||
|
C00030125
|
Dictamdiol
|
CHEMBL403868
CHEMBL404868 CHEMBL256353 |
No. 1461 |
|
||||
|
C00011939
|
Fraxinellone
|
CHEMBL257170
CHEMBL1595442 |
C075391
|
3 / 5 / 4 | No. 1461 |
|
||
|
C00030522
|
Isodictamdiol
/ (-)-Isodictamdiol |
CHEMBL403868
CHEMBL404868 CHEMBL256353 |
No. 1461 |
|
||||
|
C00030329
|
Fraxinellonone
|
CHEMBL403869
|
No. 8112 |
|
Human Protein / Gene in interactions
6 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00011939 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00011939 | 3 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003723 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003719 | 0 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00003719 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00011939 | 1 / 1 |
9 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00003719
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00003723
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00003723
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00003723
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00003723
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00003723
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00003723
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00003723
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00003723
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (5)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
KEGG DISEASE (5)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|