Species

KNApSAcK Entry

Organism name Scorzonera cretica
Genus Scorzonera
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Scorzonera cretica
Linked NCBI taxonomy ID 268092
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003749 External link 512 Lupeol
/ Lupenol
/ (+)-Lupenol
CHEMBL289191
CHEMBL459702
C010480
3 / 0 / 0 2 / 6 No. 23 No. 51
C00003750 External link 512 Lupeol acetate
CHEMBL453802
CHEMBL1097034
C055329
1 / 0 / 0 No. 23 No. 51
C00003757 External link 512 Taraxasterol
CHEMBL497525
C079988
No. 23 No. 51
C00019220 External link 512 Lupenone
CHEMBL486393
CHEMBL575188
3 / 4 / 2 No. 23 No. 51
C00046390 External link 512 Scorzocreticoside I
/ (-)-Scorzocreticoside I
No. 122 No. 15
C00046226 External link 512 Oleanol acetate
No. 177
C00045970 External link 512 Germanicol acetate
No. 177
C00046389 External link 512 Scorzocreticin
No. 1122 No. 29
C00046391 External link 512 Scorzocreticoside II
/ (-)-Scorzocreticoside II
No. 1615

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11388 DNA topoisomerase 2-alpha Isomerase C00003749 C00003750 0 / 0
Q8TDU6 G-protein coupled bile acid receptor 1 Steroid-like ligand receptor C00019220 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00003749 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003749 0 / 0
P14679 Tyrosinase Oxidoreductase C00019220 4 / 2
Q96RI1 Bile acid receptor NR1H4 C00019220 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00003749
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) C00003749

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679

KEGG DISEASE (2)

KEGG name UniProt
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)

Diseases related to CTD interactions

6 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006528 Carcinoma, Hepatocellular C00003749
D009202 Cardiomyopathies C00003749
D006937 Hypercholesterolemia C00003749
D009374 Neoplasms, Experimental C00003749
D012878 Skin Neoplasms C00003749
D014947 Wounds and Injuries C00003749