| Organism name | Aeonium decorum | 
|---|---|
| Genus | Aeonium | 
| Family | Crassulaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Aeonium decorum | 
|---|---|
| Linked NCBI taxonomy ID | 111149 | 
| Linked level | species | 
| Family in NCBI taxonomy | Crassulaceae | 
|---|---|
| ID | 3781 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | eudicotyledons | 
|---|---|
| ID | 71240 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00004635   | Isorhamnetin / 3'-O-Methylquercetin / 3,4',5,7-Tetrahydroxy-3'-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one | CHEMBL379064 | C047368 | 12 / 10 / 13 | 10 / 0 | No. 3 | No. 15 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00004635 | 0 / 0 | 
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00004635 | 1 / 1 | 
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00004635 | 0 / 0 | 
| P04792 | Heat shock protein beta-1 | Unclassified protein | C00004635 | 2 / 1 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00004635 | 0 / 0 | 
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00004635 | 4 / 4 | 
| P04745 | Alpha-amylase 1 | Enzyme | C00004635 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00004635 | 0 / 0 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00004635 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00004635 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00004635 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00004635 | 1 / 2 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) | C00004635 | 
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | C00004635 | 
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor | C00004635 | 
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00004635 | 
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | C00004635 | 
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 | C00004635 | 
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) | C00004635 | 
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) | C00004635 | 
| 4973 | OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1 | oxidized low density lipoprotein (lectin-like) receptor 1 | C00004635 | 
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 | C00004635 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #606595 | Charcot-marie-tooth disease, axonal, type 2f; cmt2f | P04792 | 
| #137750 | Glaucoma 1, open angle, a; glc1a | Q16678 | 
| #231300 | Glaucoma 3, primary congenital, a; glc3a | Q16678 | 
| #137760 | Glaucoma, primary open angle; poag | Q16678 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #608634 | Neuronopathy, distal hereditary motor, type iib; hmn2b | P04792 | 
| #604229 | Peters anomaly | Q16678 | 
| #278300 | Xanthinuria, type i | P47989 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00856 | Distal hereditary motor neuropathies (dHMN) | P04792
                            (related) | 
| H00192 | Xanthinuria | P47989
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00612 | Primary open angle glaucoma | Q16678
                            (related) | 
| H01075 | Peters anomaly | Q16678
                            (related) | 
| H01159 | Anterior segment dysgenesis (ASD) | Q16678
                            (related) | 
| H01203 | Primary congenital glaucoma (PCG) | Q16678
                            (related) |