Species

KNApSAcK Entry

Organism name Anthyllis sericea
Genus Anthyllis
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Anthyllis
Linked NCBI taxonomy ID 118889
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005157 External link 512 Panasenoside
CHEMBL500233
CHEMBL1375795
CHEMBL2032411
12 / 2 / 2 No. 1 No. 15
C00005401 External link 512 Quercetin 3-robinoside
/ Quercetin 3-O-robinoside
/ Quercetin 3-O-robinobioside
/ Quercetin 3-O-rhamnosyl-(1->6)-galactoside
CHEMBL32579
CHEMBL310754
CHEMBL182108
CHEMBL226335
CHEMBL502782
CHEMBL1436093
CHEMBL1532989
25 / 18 / 16 No. 1 No. 15
C00005534 External link 512 Isorhamnetin 3-glucosyl-(1->2)-galactoside
No. 1 No. 15
C00005776 External link 512 Syringetin 3-galactoside
CHEMBL1600723
CHEMBL2165404
3 / 3 / 7 No. 2 No. 15
C00005574 External link 512 Isorhamnetin 3-glucosyl-(1->2)-galactoside-7-glucoside
No. 5 No. 15
C00005567 External link 512 Isorhamnetin 3-glucosyl-(1->2)-[rhamnosyl-(1->6)-galactoside]
No. 5 No. 15

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme C00005157 C00005401 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005157 C00005401 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00005157 C00005401 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005157 C00005401 1 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005157 C00005401 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00005157 C00005776 0 / 0
P06276 Cholinesterase Hydrolase C00005401 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00005401 1 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00005401 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005157 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005401 1 / 1
O75496 Geminin Unclassified protein C00005157 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00005401 0 / 0
P27487 Dipeptidyl peptidase 4 S9B C00005401 0 / 1
Q9Y253 DNA polymerase eta Enzyme C00005157 1 / 1
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00005401 0 / 0
P14679 Tyrosinase Oxidoreductase C00005401 4 / 2
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00005401 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00005401 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00005401 3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00005401 2 / 0
P03372 Estrogen receptor NR3A1 C00005401 1 / 1
P22303 Acetylcholinesterase Hydrolase C00005401 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005401 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00005157 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005157 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00005401 4 / 3
P48147 Prolyl endopeptidase S9A C00005401 0 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00005401 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00005401 0 / 3
P46063 ATP-dependent DNA helicase Q1 Enzyme C00005157 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00005401 0 / 0
O00255 Menin Unclassified protein C00005776 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00005776 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (22)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#614490 Blood group, junior system; jr Q9UNQ0
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (24)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00032 Thyroid cancer P27487 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00192 Xanthinuria P47989 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)