Species

KNApSAcK Entry

Organism name Styphnolobium japonicum (L.) Schott
Genus Styphnolobium
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Sophora japonica
Linked NCBI taxonomy ID 3897
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (12)

Species Activity
Styphnolobium japonicum (L.) Schott Abortifacient
Styphnolobium japonicum (L.) Schott Analgesic
Styphnolobium japonicum (L.) Schott Antibacterial
Styphnolobium japonicum (L.) Schott Anticancer
Styphnolobium japonicum (L.) Schott Antifertility
Styphnolobium japonicum (L.) Schott Antiseptic
Styphnolobium japonicum (L.) Schott Astringent
Styphnolobium japonicum (L.) Schott Emetic
Styphnolobium japonicum (L.) Schott Estrogenic
Styphnolobium japonicum (L.) Schott Hemostat
Styphnolobium japonicum (L.) Schott Laxative
Styphnolobium japonicum (L.) Schott toxic

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005165 External link 512 Sophoraflavonoloside
/ Kaempferol 3-O-sophoroside
/ Kaempferol 3-O-beta-sophoroside
CHEMBL500233
CHEMBL1375795
CHEMBL2032411
C064309
12 / 2 / 2 6 / 4 No. 1 No. 15

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme C00005165 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005165 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005165 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005165 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00005165 0 / 0
O75496 Geminin Unclassified protein C00005165 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005165 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00005165 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005165 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00005165 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005165 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00005165 0 / 0

6 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
3146 HMGB1, HMG1, HMG3, SBP-1 high mobility group box 1 C00005165
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00005165
6401 SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 selectin E C00005165
7097 TLR2, CD282, TIL4 toll-like receptor 2 C00005165
7099 TLR4, ARMD10, CD284, TLR-4, TOLL toll-like receptor 4 C00005165
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00005165

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#232300 Glycogen storage disease ii P10253
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (2)

KEGG name UniProt
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

4 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003920 Diabetes Mellitus C00005165
D006967 Hypersensitivity C00005165
D007249 Inflammation C00005165
D009369 Neoplasms C00005165