Species

KNApSAcK Entry

Organism name Hibiscus vitifolius
Genus Hibiscus
Family Malvaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hibiscus
Linked NCBI taxonomy ID 47605
Linked level genus

Family

Family in NCBI taxonomy Malvaceae
ID 3629

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00013990 External link 512 3,6,7,8,3',4'-Hexahydroxy-5'-methoxyflavone 7-neohesperidoside
/ 7-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxy-5-methoxyphenyl)-3,6,8-trihydroxy-4H-1-benzopyran-4-one
No. 1 No. 15
C00005691 External link 512 Gossypetin 8-glucuronide
CHEMBL1822703
C087346
0 / 1 No. 2 No. 15
C00005690 External link 512 Gossypetin 8-glucoside
CHEMBL402915
CHEMBL1337379
C022944
9 / 11 / 16 No. 2 No. 15

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P24941 Cyclin-dependent kinase 2 Cdc2 C00005690 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00005690 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00005690 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00005690 2 / 2
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005690 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00005690 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00005690 0 / 0
O00255 Menin Unclassified protein C00005690 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00005690 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#119900 Digital clubbing, isolated congenital P15428
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (16)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D004487 Edema C00005691