Polygonum panjutinii
Species
KNApSAcK Entry
| Organism name | Polygonum panjutinii |
|---|---|
| Genus | Polygonum |
| Family | Polygonaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Aconogonon panjutinii |
|---|---|
| Linked NCBI taxonomy ID | 701363 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Polygonaceae |
|---|---|
| ID | 3615 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00008882
|
Gallocatechin 3-O-gallate
|
CHEMBL297453
CHEMBL311663 CHEMBL126079 CHEMBL338988 CHEMBL264938 |
49 / 48 / 54 | No. 219 | No. 14 |
|
Human Protein / Gene in interactions
49 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00008882 | 0 / 0 |
| O95342 | Bile salt export pump | drug | C00008882 | 2 / 1 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00008882 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00008882 | 0 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00008882 | 2 / 2 |
| P08246 | Neutrophil elastase | S1A | C00008882 | 2 / 1 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00008882 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00008882 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00008882 | 1 / 1 |
| P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | Enzyme | C00008882 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00008882 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00008882 | 3 / 1 |
| P02768 | Serum albumin | Secreted protein | C00008882 | 0 / 0 |
| P49327 | Fatty acid synthase | Transferase | C00008882 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00008882 | 1 / 2 |
| P51570 | Galactokinase | Enzyme | C00008882 | 1 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00008882 | 2 / 3 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00008882 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00008882 | 0 / 0 |
| P50281 | Matrix metalloproteinase-14 | M10A | C00008882 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00008882 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00008882 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00008882 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00008882 | 5 / 9 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00008882 | 2 / 3 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00008882 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00008882 | 0 / 0 |
| P09237 | Matrilysin | M10A | C00008882 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00008882 | 1 / 3 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00008882 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00008882 | 2 / 2 |
| P00374 | Dihydrofolate reductase | Oxidoreductase | C00008882 | 1 / 1 |
| P26358 | DNA (cytosine-5)-methyltransferase 1 | Transferase | C00008882 | 2 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00008882 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00008882 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00008882 | 0 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00008882 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00008882 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00008882 | 0 / 0 |
| Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | CMGC dual-specificity kinase DYRK1 | C00008882 | 1 / 0 |
| O14746 | Telomerase reverse transcriptase | Enzyme | C00008882 | 5 / 5 |
| P10415 | Apoptosis regulator Bcl-2 | Other cytosolic protein | C00008882 | 0 / 7 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00008882 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00008882 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00008882 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00008882 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00008882 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00008882 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00008882 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (48)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #609135 | Aplastic anemia |
O14746
|
| #210900 | Bloom syndrome; blm |
P54132
|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #604121 | Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant; adcadn |
P26358
|
| #605479 | Cholestasis, benign recurrent intrahepatic, 2; bric2 |
O95342
|
| #601847 | Cholestasis, progressive familial intrahepatic, 2; pfic2 |
O95342
|
| #162800 | Cyclic neutropenia |
P08246
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #613989 | Dyskeratosis congenita, autosomal dominant, 2; dkca2 |
O14746
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #230200 | Galactokinase deficiency |
P51570
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
P37231 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #114550 | Hepatocellular carcinoma |
P08581
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P04626
|
| #613839 | Megaloblastic anemia due to dihydrofolate reductase deficiency |
P00374
|
| #615134 | Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 |
O14746
|
| #614104 | Mental retardation, autosomal dominant 7; mrd7 |
Q13627
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #614116 | Neuropathy, hereditary sensory, type ie; hsn1e |
P26358
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P37231
|
| #167000 | Ovarian cancer |
P04626
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #614742 | Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 |
O14746
|
| #178500 | Pulmonary fibrosis, idiopathic; ipf |
O14746
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (54)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00764 | Cri du chat syndrome |
O14746
(related)
|
| H01132 | Aplastic anemia (AA) |
O14746
(related)
|
| H01299 | Idiopathic pulmonary fibrosis |
O14746
(related)
|
| H00022 | Bladder cancer |
O14746
(marker)
P04626 (related) |
| H00024 | Prostate cancer |
O14746
(marker)
|
| H00624 | Familial cholestasis |
O95342
(related)
|
| H01197 | Dihydrofolate reductase (DHFR) deficiency |
P00374
(related)
|
| H00018 | Gastric cancer |
P04626
(related)
P08581 (related) P10415 (related) |
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00026 | Endometrial Cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00028 | Choriocarcinoma |
P04626
(related)
P08253 (related) P10415 (related) |
| H00030 | Cervical cancer |
P04626
(related)
P10415 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P08581 (related) P35354 (related) |
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00025 | Penile cancer |
P08253
(related)
P35354 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00021 | Renal cell carcinoma |
P08581
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P10415
(related)
|
| H00013 | Small cell lung cancer |
P10415
(related)
|
| H00041 | Kaposi's sarcoma |
P10415
(related)
|
| H00054 | Nasopharyngeal cancer |
P10415
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00070 | Galactosemia |
P51570
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|