Species

KNApSAcK Entry

Organism name Streptomyces hygroscopicus subsp. limoneus
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces hygroscopicus subsp. limoneus
Linked NCBI taxonomy ID 264445
Linked level subspecies

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00017025 External link 512 Validamycin H
C066094
No. 772
C00017813 External link 512 Validamycin G
No. 772
C00018831 External link 512 Validamycin D
No. 772
C00018830 External link 512 Validamycin C
No. 772
C00018832 External link 512 Validamycin E
No. 772
C00018608 External link 512 Valiolamine
CHEMBL9216
CHEMBL223096
CHEMBL222396
C043270
4 / 8 / 6 No. 4033
C00017814 External link 512 Validoxylamine G
/ (+)-Validoxylamine G
C050693
No. 5783

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04062 Glucosylceramidase Enzyme C00018608 6 / 4
P10253 Lysosomal alpha-glucosidase Hydrolase C00018608 1 / 1
P14410 Sucrase-isomaltase, intestinal Enzyme C00018608 1 / 1
O43451 Maltase-glucoamylase, intestinal Hydrolase C00018608 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#168600 Parkinson disease, late-onset; pd P04062
#222900 Sucrase-isomaltase deficiency, congenital; csid P14410

KEGG DISEASE (6)

KEGG name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00115 Congenital sucrase-isomaltase deficiency P14410 (related)